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The following discussion is an archived debate of the proposed deletion of the article below. Please do not modify it. Subsequent comments should be made on the appropriate discussion page (such as the article's talk page or in a deletion review). No further edits should be made to this page.

The result was redirect to Automated tissue image systems. no evidence of actual notability, but redirect per Tim vikers DGG ( talk ) 02:48, 6 May 2010 (UTC)[reply]

Automated Imaging Microscope System

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Automated Imaging Microscope System (edit | talk | history | protect | delete | links | watch | logs | views) – (View log • AfD statistics)
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Non-notable system. A Google search gives 54 hits, several of them WP or its mirrors, none indicating any notability. A PubMed search renders not a single hit. The system seems to have been published originally in the Linux Journal, not a usual venue for developments in the life sciences. This article is part of a walled-garden created by User:Sgaran, see also Wikipedia:Articles for deletion/Steven A. Garan. In the absence of any evidence that this meets WP:N, the article should be deleted. --Crusio (talk) 19:02, 29 April 2010 (UTC)[reply]


  • KEEP Google returns about 2,450 for "Automated Imaging Microscope System (AIMS)" — Preceding unsigned comment added by Sgaran (talk • contribs)
  • KEEPAutomated Imaging Microscope System (AIMS) played an important role in shedding light on the effects of caloric restriction on cell populations in the hypothalamus. AIMS was the first fully automated system that could scan large areas of tissue, reconstruct these large sections digitally, count cells that expressed different receptors and create a three dimensional volumetric model of the densities of those populations. A list of the publications that resulted is shown below:
  • Yaghmaie F, Saeed O, Garan SA, Voelker MA, Sternberg H, Timiras PS (February 2010). "Estrogen receptor-alpha immunoreactivity in the arcuate hypothalamus of young and middle-aged female mice". Neuro Endocrinology Letters 31 (1): 15. PMID 20150877.
  • Gouw, A; Mahuron, K; Manandhar, S; Tin, A; Garan, S; Hakimi, P; Timiras, P (2009). "The plasticity of neural cell reprogramming: Role of growth factors in inducing neuroglia to neuron and to neural precursor cell". Experimental Gerontology 44: 129. doi:10.1016/j.exger.2008.08.025.
  • Gouw AM, Panchal H, Mahuron K, Wadhwani H, Manandhar S, Garan SA, Tin A, Timiras PS (June 15, 2008). "The Potential Role of Epidermal Growth Factor (EGF) and Curcumin in Transforming Neuroglia into Neurons". The Endocrine Society 90th Annual Meeting. San Francisco, CA. Retrieved February 27, 2010.
  • Garan, S; Yaghmaie, F; Saeed, O; Gouw, A; Freitag, W; Voelker, M; Jafar, P; Kaur, J et al. (2007). "Novel methods in computer-assisted tissue analysis: Customized regional targeting of both cytoplasmic and nuclear-stained tissue". Experimental Gerontology 42: 141–2. doi:10.1016/j.exger.2006.06.015.
  • Yaghmaie F, Saeed O, Garan SA, et al. (November 2006). "Age-dependent loss of insulin-like growth factor-1 receptor immunoreactive cells in the supraoptic hypothalamus is reduced in calorically restricted mice". International Journal of Developmental Neuroscience 24 (7): 431–6. doi:10.1016/j.ijdevneu.2006.08.008. PMID 17034982.
  • Yaghmaie, F; Saeed, O; Garan, S; Gouw, A; Jafar, P; Kaur, J; Nijjar, S; Timiras, P et al. (2007). "Tracking changes in hypothalamic IGF-1 sensitivity with aging and caloric restriction". Experimental Gerontology 42: 148–9. doi:10.1016/j.exger.2006.06.043.
  • Saeed O, Yaghmaie F, Garan SA, et al. (February 2007). "Insulin-like growth factor-1 receptor immunoreactive cells are selectively maintained in the paraventricular hypothalamus of calorically restricted mice". International Journal of Developmental Neuroscience 25 (1): 23–8. doi:10.1016/j.ijdevneu.2006.11.004. PMID 17194562.
  • Yaghmaie F, Saeed O, Garan SA, et al. (November 2006). "Age-dependent loss of insulin-like growth factor-1 receptor immunoreactive cells in the supraoptic hypothalamus is reduced in calorically restricted mice". International Journal of Developmental Neuroscience 24 (7): 431–6. doi:10.1016/j.ijdevneu.2006.08.008. PMID 17034982.
  • Yaghmaie, Farzin; Saeed, Omar; Garan, Steven A.; Gouw, Arvin M.; Tran, Tien; Ho, Jacqueline; Zhao, Liu Y.; Voelker, Mark A. et al. (March 2006). "A Study of Insulin-like Growth Factor-I Receptor Immunoreactivity in the Supraoptic Nucleus of Young and Old Female B6D2F1 Mice". The FASEB Journal 20 (4): A536.
  • Yaghmaie F, Saeed O, Garan SA, Freitag W, Timiras PS, Sternberg H (June 2005). "Caloric restriction reduces cell loss and maintains estrogen receptor-alpha immunoreactivity in the pre-optic hypothalamus of female B6D2F1 mice". Neuro Endocrinology Letters 26 (3): 197–203. PMID 15990721.
  • Yaghmaie F, Garan SA, Saeed O, Freitag W, Timiras PS, Sternberg H, Voelker M (November–December 2004). "A survey of estrogen receptor-alpha immunoreactivity in the hypothalamus of young, old, and old-calorie restricted female B6D2F1 mice". Experimental Gerontology 39 (11–12): 1771.
  • Voelker M, Yaghmaie F, Garan SA, Sternberg H (November–December 2004). "Protocol for higher resolution histological images of the mammalian brain". Experimental Gerontology 39 (11–12): 1770.
  • Yaghmaie F, Garan SA, Massaro M, Timiras PS (January 2003). "A comparison of estrogen receptor-alpha immunoreactivity in the arcuate hypothalamus of young and middle-aged C57BL6 female mice". Experimental Gerontology 38 (1–2): 220.
  • Garan SA, Neudorf J, Tonkin J, McCook LR, Timiras PS (December 2000). "Creating Three-Dimensional Neuronal Maps of the Mouse Hypothalamus Using an Automated Imaging Microscope System". Experimental Gerontology 35 (9–10): 1421.
  • Neudorf, Jason; Garan, Steven A. (February 2000). "Automated Imaging Microscope System". Linux Journal (70): 32–5.

The editors of the journals listed above all agree that the discoveries that resulted in the work of the Automated Imaging Microscope System were important. — Preceding unsigned comment added by Sgaran (talk • contribs)

  • Comment Many of the above "publications" are in fact only meeting abstracts (often not peer reviewed). The others are articles that have not or only sporadically been cited, not showing any notability for this system. If I search for "Automated Imaging Microscope System (AIMS)" on Google, I get 25 hits, not 2450. --Crusio (talk) 11:48, 1 May 2010 (UTC)[reply]
  • Comment - Dear wikipedia colleagues, I would like to update you on a issue that has become disturbing to me. A few days ago Wim Crusio and I had a disagreement over the word "Phenomics" which has been used in many scientific publications and online dictionaries. Wim Crusio has been changing the wiki entry to re-direct it to the word "Phenotype" and I have tried to keep the word as a stand alone term. After his repeated failed attempts to redirect the word to "Phenotype" he has decided to carry out a reprehensible vendetta against myself, my work and my co-researcher who passed away in 2008. As you can see by Wim Crusio's edit history on the following items, he started to delete and alter the following items, on April 29, 2010, which was directly after our disagreement over the word "Phenomics" :
Steven A. Garan,  
Aging Research Centre,  
Automated Imaging Microscope System,  
Paola S. Timiras

I hope the contributors to wikipedia do not encourage this kind of childish behavior. If Wim Crusio has a disagreement regarding an issue with any of my wikipedia colleagues, I would hope to stand by them should a person like Wim Crusio carry out a similar campaign. What I find utterly reprehensible is Wim Crusio's sudden interest in my co-researcher of ten years Paola S. Timiras. She passed away in September of 2008 and starting on April 29, 2010, his actions in altering her page are clearly an act driven not my any scientific motivation, but instead by a malicious desire for revenge.

Steven A. Garan

I believe that the appropriate place for discussions about the articles would be their respective talk pages, shall we continue there? Glad to see that you are willing to communicate. --Nuujinn (talk) 18:47, 1 May 2010 (UTC)[reply]
The above discussion is preserved as an archive of the debate. Please do not modify it. Subsequent comments should be made on the appropriate discussion page (such as the article's talk page or in a deletion review). No further edits should be made to this page.
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