hypertrophy

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English

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English Wikipedia has an article on:
Wikipedia
Hypertrophy results from an increase in cell size, whereas hyperplasia stems from an increase in cell number

Etymology

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From French hypertrophie, from Ancient Greek ὑπέρ (hupér, over, excessive) + τροφή (trophḗ, nourishment), equivalent to hyper- +‎ -trophy.

Pronunciation

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Noun

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hypertrophy (countable and uncountable, plural hypertrophies)

  1. (countable, medicine) An increase in the size of an organ or tissue due to the enlargement of its individual cells.
    • 2010 January 29, Anita Woods et al., “Control of chondrocyte gene expression by actin dynamics: a novel role of cholesterol/Ror-α signalling in endochondral bone growth”, in Journal of Cellular and Molecular Medicine[1], volume 13, →DOI:
      Ectopic chondrocyte hypertrophy has been demonstrated in OA, suggesting that the pathogenetical process involves a recapitulation of endochondral ossification [ 11 – 13 ].
  2. (uncountable, bodybuilding) Increase in muscle size through increased size of individual muscle cells; a result of weightlifting, and other exercise. It differs from muscle hyperplasia, which is the formation of new muscle cells.

Antonyms

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Coordinate terms

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Derived terms

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Translations

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Verb

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hypertrophy (third-person singular simple present hypertrophies, present participle hypertrophying, simple past and past participle hypertrophied)

  1. (intransitive, of a tissue or organ) To increase in size.
    Antonym: atrophy
  2. (by extension) To enlarge or extend.
    • 2020 January 29, Douglas Groothuis, “Texts, Graphics, and Culture: On the Decline of Reading and Civilization”, in Douglas Groothuis, Ph.D.: Christian Philosopher and Apologist[2], archived from the original on 27 January 2023:
      But when text hypertrophies into a riot of contending inscripturations, we lose too much of what matters most in writing.
    • 2020, Merlin Sheldrake, Entangled Life, page 76:
      Like a well-exercised muscle, 'network' has hypertrophied into a master concept.

Translations

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