Deep interpretability for GWAS
… Deep networks can be used to model these interactions, … deep interpretability technique
named DeepLIFT to show that known diabetes genetic risk factors can be identified using deep …
named DeepLIFT to show that known diabetes genetic risk factors can be identified using deep …
Interpretable deep neural networks for more accurate predictive genomics and genome-wide association studies
A Badré - 2023 - shareok.org
… more interpretable if its decisions are easier for humans to understand. The terms interpretable
… In this dissertation, interpretable machine learning refers to gaining meaningful insights …
… In this dissertation, interpretable machine learning refers to gaining meaningful insights …
[HTML][HTML] Interpretable deep learning translation of GWAS and multi-omics findings to identify pathobiology and drug repurposing in Alzheimer's disease
… deep learning framework to identify disease-associated genes (NETTAG). We leverage
non-coding GWAS … In summary, NETTAG offers a deep learning methodology that utilizes GWAS …
non-coding GWAS … In summary, NETTAG offers a deep learning methodology that utilizes GWAS …
Deep Learning for Efficient GWAS Feature Selection
K Li - arXiv preprint arXiv:2312.15055, 2023 - arxiv.org
… evolve, our extended deep neural network approach emerges as a potent tool for researchers
seeking accurate and interpretable feature selection in the complex landscape of GWAS. …
seeking accurate and interpretable feature selection in the complex landscape of GWAS. …
DeepCOMBI: explainable artificial intelligence for the analysis and discovery in genome-wide association studies
B Mieth, A Rozier, JA Rodriguez… - NAR genomics and …, 2021 - academic.oup.com
… , deep Taylor-based explanation techniques (48) have not yet been applied in the field of
GWAS and … To make LRP applicable as an explanation method for GWAS data, we use a very …
GWAS and … To make LRP applicable as an explanation method for GWAS data, we use a very …
GenNet framework: interpretable deep learning for predicting phenotypes from genetic data
A van Hilten, SA Kushner, M Kayser, MA Ikram… - Communications …, 2021 - nature.com
… While genome-wide association studies (GWAS) have … Recent GWAS studies with increasingly
large sample sizes are … To illustrate, the latest GWAS for body height based on 700,000 …
large sample sizes are … To illustrate, the latest GWAS for body height based on 700,000 …
[BOOK][B] Deep learning for genome-wide association studies
D Sharma - 2021 - search.proquest.com
… and interpretability of black-box models, including the motivations and goals of interpretability
research. We then give a brief survey of current interpretability techniques for deep …
research. We then give a brief survey of current interpretability techniques for deep …
Genome‐wide association study‐based deep learning for survival prediction
… massive GWAS data … deep learning to effectively extract features from the GWAS data.
Therefore, we develop and apply the DNN survival model to build an accurate and interpretable …
Therefore, we develop and apply the DNN survival model to build an accurate and interpretable …
Designing interpretable deep learning applications for functional genomics: a quantitative analysis
… in interpretable deep-learning applications and the millions of individuals included in
genome-wide association studies (GWAS) (… Around these topics, GWAS consortia have formed …
genome-wide association studies (GWAS) (… Around these topics, GWAS consortia have formed …
DeepPerVar: a multi-modal deep learning framework for functional interpretation of genetic variants in personal genome
… variants in a GWAS risk locus. Finally, we release the proposed deep learning model as a
… not readily interpretable as the linear counterparts. However, a common practice to interpret …
… not readily interpretable as the linear counterparts. However, a common practice to interpret …