Extreme scale de novo metagenome assembly

E Georganas, R Egan, S Hofmeyr… - … Conference for High …, 2018 - ieeexplore.ieee.org
… MetaHipMer implements an iterative de Bruijn graph approach similar to IDBA-UD [6] …
metagenome assembler that achieves comparable quality to the state-of-theart tools, but scales

HipMer: an extreme-scale de novo genome assembler

E Georganas, A Buluç, J Chapman, S Hofmeyr… - Proceedings of the …, 2015 - dl.acm.org
… Since metagenome assembly is not within the original … errors in the scaffolding of a
metagenome, we will only execute … HipMer to properly scaffold a metagenome at scale. As shown …

Genovo: De Novo Assembly for Metagenomes

J Laserson, V Jojic, D Koller - Journal of Computational Biology, 2011 - liebertpub.com
… for our metagenomic sequencing method, as well as the score we propose for de novo
We adopt a view of the metagenomic sequence assembly problem in which two competing …

Accelerating large scale de novo metagenome assembly using GPUs

MG Awan, S Hofmeyr, R Egan, N Ding… - Proceedings of the …, 2021 - dl.acm.org
… Hipmer: an extreme-scale de novo genome assembler. In SC’15: Proceedings of the …
Extreme scale de novo metagenome assembly. In SC18: International Conference for High …

18 Extreme-Scale De Novo Genome Assembly

E Georganas, S Hofmeyr, L Oliker… - Exascale scientific …, 2017 - api.taylorfrancis.com
… algorithms for de novo assembly with the ambition to scale to … -performance de novo assembler
designed to scale to massive … Ray meta: Scalable de novo metagenome assembly and …

DIME: A Novel Framework for De Novo Metagenomic Sequence Assembly

X Guo, N Yu, X Ding, J Wang, Y Pan - Journal of Computational …, 2015 - liebertpub.com
… In order to address the aforementioned problems, we present a novel framework based on
DIvide, conquer, and MErge strategies (DIME) for de novo metagenomic assembly. The four …

De novo metagenomic assembly reveals abundant novel major lineage of Archaea in hypersaline microbial communities

P Narasingarao, S Podell, JA Ugalde… - The ISME …, 2012 - academic.oup.com
… unusual archaeal genomes by de novo metagenomic assembly of multiple, … assembled
genomes to visualize these novel archaea, which were highly abundant in the 0.1–0.8 μm size

Long-read based de novo assembly of low-complexity metagenome samples results in finished genomes and reveals insights into strain diversity and an active phage …

V Somerville, S Lutz, M Schmid, D Frei, A Moser… - BMC microbiology, 2019 - Springer
… Here, we demonstrate the feasibility of complete de novo genome assembly of all dominant
strains from low-complexity NWCs based on whole metagenomics shotgun sequencing data…

Genovo: De Novo Assembly for Metagenomes

J Laserson, V Jojic, D Koller - Annual International Conference on …, 2010 - Springer
… to three state of the art short read assembly programs in terms of the number of … of a de
novo assembly using no external information. The comparison is conducted on 8 metagenomic

New approaches for metagenome assembly with short reads

M Ayling, MD Clark, RM Leggett - Briefings in bioinformatics, 2020 - academic.oup.com
… The low coverage of most species means de novo assembly is unlikely unless the genome
in question is relatively small, and instead we are reliant on reference genomes or gene …