Prijeđi na sadržaj

Imidapril

Izvor: Wikipedija
Imidapril
(IUPAC) ime
(4S)-3-[(2S)-2- {[(2S)-1-etoksi-1-okso-4-fenilbutan-2-il]amino}propanoil]-1-metil-2-oksoimidazolidin-4-karboksilna kiselina
Klinički podaci
AHFS/Drugs.com Internacionalno ime leka
Identifikatori
CAS broj 89371-37-9
ATC kod C09AA16
PubChem[1][2] 5464343
ChemSpider[3] 4576628
UNII BW7H1TJS22 DaY
KEGG[4] D08068 DaY
ChEMBL[5] CHEMBL317094 DaY
Hemijski podaci
Formula C20H27N3O6 
Mol. masa 405,444 g/mol
SMILES eMolekuli & PubHem
Farmakoinformacioni podaci
Trudnoća ?
Pravni status

Imidapril je ACE inhibitor koji se koristi kao antihipertenzivni lek za tretman hroničnog zatajenja srca.[6]

Reference

[uredi | uredi kod]
  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1. 
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.  edit
  4. Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H. 
  5. Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594.  edit
  6. Robinson, D. M.; Curran, M. P.; Lyseng-Williamson, K. A. (2007). „Imidapril: A review of its use in essential hypertension, Type 1 diabetic nephropathy and chronic heart failure”. Drugs 67 (9): 1359–1378. PMID 17547476.