Mozavaptan
(IUPAC ) ime
N -[4-(5-Dimethylamino-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)phenyl]-2-methylbenzamide
Klinički podaci
Identifikatori
CAS broj
137975-06-5
ATC kod
nije dodeljen
PubChem [ 1] [ 2] 119369
ChemSpider [ 3] 106618
Hemijski podaci
Formula
C 27 H 29 N 3 O 2
Mol. masa
427.53 g/mol
SMILES
eMolekuli PubHem
InChI InChI=1S/C27H29N3O2/c1-19-9-4-5-10-22(19)26(31)28-21-16-14-20(15-17-21)27(32)30-18-8-13-24(29(2)3)23-11-6-7-12-25(23)30/h4-7,9-12,14-17,24H,8,13,18H2,1-3H3,(H,28,31) Y Y
Farmakoinformacioni podaci
Trudnoća
?
Pravni status
℞ Prescription only
Način primene
Oralno
Mozavaptan (INN ) je antagonist vazopresinskog receptora u prodaji od strane kompanije Otsuka . On je odobren u Japanu oktobra 2006. za hiponatremiju (niske nivoe krvnog natrijuma ) uzrokovane sindromom neodgovarajućeg izlučivanja antidiuretskog hormona (SIADH) usled tumora koji proizvodi ADH.[ 4] [ 5]
↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.” . Drug Discov Today 15 (23-24): 1052-7. DOI :10.1016/j.drudis.2010.10.003 . PMID 20970519 . edit ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4 : 217-241. DOI :10.1016/S1574-1400(08)00012-1 . ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining” . J Cheminform 2 (1): 3. DOI :10.1186/1758-2946-2-3 . PMID 20331846 . edit ↑ H. Spreitzer (November 20, 2006). „Neue Wirkstoffe - Conivaptan” (German). Österreichische Apothekerzeitung (24/2006). ↑ „Prous Science: Molecule of the Month November 2006” .
Šablon:Diuretici
Šablon:Neuropeptidni ligandi
