Stearoil-KoA 9-desaturaza
| Stearoil-KoA 9-desaturaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.19.1 | ||||||||
| CAS broj | 9014-34-0 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Stearoil-KoA 9-desaturaza (EC 1.14.19.1, Delta9-desaturaza, acil-KoA desaturaza, masno kiselinska desaturaza, stearoil-KoA, vodonik-donor:kiseonik oksidoreduktaza) je enzim sa sistematskim imenom stearoil-KoA,ferocitohrom-b5:kiseonik oksidoreduktaza (9,10-devodonikacija).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju:
- stearoil-KoA + 2 ferocitohrom b5 + O2 + 2 H+ oleoil-KoA + 2 fericitohrom b5 + 2H2O
Ovaj enzim sadrži gvožđe. Enzim iz jetre pacova je deo sistema koji obuhvata citohrom b5 i EC 1.6.2.2, citohrom-b5 reduktazu.
Reference
[уреди | уреди извор]- ^ Fulco, A.J. & Bloch, K. (1964). „Cofactor requirements for the formation of Δ9-unsaturated fatty acids in Mycobacterium phlei”. J. Biol. Chem. 239: 993—997. PMID 14167617.
- ^ Oshino, N., Imai, Y. and Sato, R. (1966). „Electron-transfer mechanism associated with fatty acid desaturation catalyzed by liver microsomes”. Biochim. Biophys. Acta. 128: 13—27. PMID 4382040.
- ^ Oshino, N., Imai, Y. and Sato, R. (1971). „A function of cytochrome b5 in fatty acid desaturation by rat liver microsomes”. J. Biochem. (Tokyo). 69: 155—167. PMID 5543646.
- ^ Strittmatter, P., Sputz, L., Corcoran, D., Rogers, M.J., Setlow, B. and Redline, R. (1974). „Purification and properties of rat liver microsomal stearyl coenzyme A desaturase”. Proc. Natl. Acad. Sci. USA. 71: 4565—4569. PMID 4373719.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
[уреди | уреди извор]- Stearoyl-CoA+9-desaturase на US National Library of Medicine Medical Subject Headings (MeSH)
