filipin III (Q2073868)

Filimarisin (English)

(3S,4S,6S,8R,10R,12S,14R,16R,17E,19E,21E,23E,25E,27R,28R)-4,6,8,10,12,14,16,27-octahydroxy-3-[(1S)-1-hydroxyhexyl]-17,28-dimethyl-1-oxacyclooctacosa-17,19,21,23,25-pentaen-2-one

9 October 2016

stereoisomer of

1 reference

based on heuristic

inferred from InChI

Oxacyclooctacosa-17,19,21,23,25-pentaen-2-one, 4,6,8,10,12,14,16,27-octahydroxy-3-(1-hydroxyhexyl)-17,28-dimethyl-

1 reference

based on heuristic

inferred from InChI

chemical formula

C₃₅H₅₈O₁₁

1 reference

Filimarisin (English)

9 October 2016

canonical SMILES

CCCCCC(C1C(CC(CC(CC(CC(CC(CC(C(=CC=CC=CC=CC=CC(C(OC1=O)C)O)C)O)O)O)O)O)O)O)O

1 reference

Filimarisin (English)

9 October 2016

isomeric SMILES

CCCCC[C@H]([C@@H]1[C@H](C[C@H](C[C@H](C[C@H](C[C@H](C[C@H](C[C@@H](/C(=C/C=C/C=C/C=C/C=C/[C@@H]([C@H](OC1=O)C)O)/C)O)O)O)O)O)O)O)O

1 reference

Filimarisin (English)

Streptomyces filipinensis

9 October 2016

found in taxon

3 references

Separation of the filipin complex by gradient-elution high performance liquid chromatography

Polyene antibiotics. V. Characterization of components of the filipin complex by mass spectrometry

Functional analysis of filipin tailoring genes from Streptomyces filipinensis reveals alternative routes in filipin III biosynthesis and yields bioactive derivatives

Streptomyces avermitilis

6 references

Genome mining of the Streptomyces avermitilis genome and development of genome-minimized hosts for heterologous expression of biosynthetic gene clusters

SdrA, a new DeoR family regulator involved in Streptomyces avermitilis morphological development and antibiotic production

Regio- and stereospecificity of filipin hydroxylation sites revealed by crystal structures of cytochrome P450 105P1 and 105D6 from Streptomyces avermitilis.

The autoregulator receptor homologue AvaR3 plays a regulatory role in antibiotic production, mycelial aggregation and colony development of Streptomyces avermitilis.

Transcriptomics analyses reveal global roles of the regulator AveI in Streptomyces avermitilis

Activation of cryptic phthoxazolin A production in Streptomyces avermitilis by the disruption of autoregulator-receptor homologue AvaR3.

Streptomyces miharaensis

1 reference

Identification and biocontrol efficacy of Streptomyces miharaensis producing filipin III against Fusarium wilt

Streptomyces lavenduligriseus

1 reference

Three novel polyene macrolides isolated from cultures of Streptomyces lavenduligriseus.

Streptomyces eurythermus

1 reference

Three novel polyene macrolides isolated from cultures of Streptomyces lavenduligriseus.

subject has role

antibiotic

1 reference

15 March 2018

1 reference

15 March 2018

1 reference

imported from Wikimedia project

15 March 2018

1 reference

English Wikipedia

Wikimedia import URL

https://en.wikipedia.org/w/index.php?title=Filipin&oldid=950447042

Identifiers

InChI

InChI=1S/C35H58O11/c1-4-5-11-16-31(42)34-33(44)22-29(40)20-27(38)18-25(36)17-26(37)19-28(39)21-32(43)23(2)14-12-9-7-6-8-10-13-15-30(41)24(3)46-35(34)45/h6-10,12-15,24-34,36-44H,4-5,11,16-22H2,1-3H3/b7-6+,10-8+,12-9+,15-13+,23-14+/t24-,25+,26-,27+,28-,29+,30+,31-,32+,33+,34-/m1/s1

1 reference

Filimarisin (English)

9 October 2016

2 references

Filimarisin (English)

9 October 2016

ChEBI release 2020-09-01

2 references

filipin III (English)

9 October 2016

https://commonchemistry.cas.org/detail?cas_rn=480-49-9

10 April 2021

1 reference

Filipin III (English)

9 October 2016

2 references

Filimarisin (English)

matched by identifier from

9 October 2016

Reaxys registry number

7326798

1 reference

filipin III (English)

9 October 2016

ChEBI ID

83267

mapping relation type

2 references

filipin III (English)

matched by identifier from

9 October 2016

International Chemical Identifier

InChI

InChI=1S/C35H58O11/c1-4-5-11-16-31(42)34-33(44)22-29(40)20-27(38)18-25(36)17-26(37)19-28(39)21-32(43)23(2)14-12-9-7-6-8-10-13-15-30(41)24(3)46-35(34)45/h6-10,12-15,24-34,36-44H,4-5,11,16-22H2,1-3H3/b7-6+,10-8+,12-9+,15-13+,23-14+/t24-,25+,26-,27+,28-,29+,30+,31-,32+,33+,34-/m1/s1

1 reference

ECHA Substance Infocard database

FILIPIN (English)

9 October 2016

1 reference

0 references

0 references

0 references

1 reference

ECHA Substance Infocard ID

100.164.904

27 December 2018

ECHA Substance Infocard ID

Filipin III from streptomycesfilipinensis (English)

quotation

CAS no.: 480-49-9 (English)

100.164.904

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.164.904

27 December 2018

imported from Wikimedia project

Filipin III from streptomycesfilipinensis (English)

quotation

CAS no.: 480-49-9 (English)

Nikkaji ID

J755.176B

1 reference

Japanese Wikipedia

Wikimedia import URL

https://ja.wikipedia.org/w/index.php?title=フィリピン_(化合物)&oldid=67457786

MeSH descriptor ID

D005372

subject named as

Filipin

1 reference

14 March 2018

D02.455.326.271.665.325

0 references

0 references

1 reference

filipin III (English)

reason for deprecated rank

9 October 2016

UNII

87Z59R7D14

cannot be confirmed by other sources

0 references

Natural Product Atlas ID

NPA032748

2 references

based on heuristic

inferred from InChIKey

matched by identifier from

0 references

1 reference