Taming hazardous chemistry by continuous flow technology (Q38907371)

7 September 2017

title

Taming hazardous chemistry by continuous flow technology (English)

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7 September 2017

5

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11 June 2020

Christian V Stevens

6

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11 June 2020

author name string

M Movsisyan

1

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11 June 2020

E I P Delbeke

2

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11 June 2020

J K E T Berton

3

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11 June 2020

C Battilocchio

4

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11 June 2020

publication date

25 July 2016

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7 September 2017

number of pages

37

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based on heuristic

inferred from page(s)

published in

Chemical Society Reviews

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11 June 2020

volume

45

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11 June 2020

issue

18

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11 June 2020

page(s)

4892-4928

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Flash chemistry: fast chemical synthesis by using microreactors

11 June 2020

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Green and Sustainable Chemical Synthesis Using Flow Microreactors

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Ten key issues in modern flow chemistry

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Investigation of a lithium-halogen exchange flow process for the preparation of boronates by using a cryo-flow reactor

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Integrated one-flow synthesis of heterocyclic thioquinazolinones through serial microreactions with two organolithium intermediates.

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Design and Application of a Low-Temperature Continuous Flow Chemistry Platform

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Reconfiguration of a Continuous Flow Platform for Extended Operation: Application to a Cryogenic Fluorine-Directed ortho-Lithiation Reaction

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Continuous Flow-Processing of Organometallic Reagents Using an Advanced Peristaltic Pumping System and the Telescoped Flow Synthesis of (E/Z)-Tamoxifen

21 January 2018

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The Continuous-Flow Synthesis of Carboxylic Acids using CO2 in a Tube-In-Tube Gas Permeable Membrane Reactor

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Hydrogenation in flow: Homogeneous and heterogeneous catalysis using Teflon AF-2400 to effect gas–liquid contact at elevated pressure

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Kumada-Corriu reactions in a pressure-driven microflow reactor.

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Continuous Preparation of Arylmagnesium Reagents in Flow with Inline IR Monitoring

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Continuous flow enantioselective arylation of aldehydes with ArZnEt using triarylboroxins as the ultimate source of aryl groups

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Trimethylaluminium mediated amide bond formation in a continuous flow microreactor as key to the synthesis of rimonabant and efaproxiral

21 January 2018

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Practical and economic lithiations of functionalized arenes and heteroarenes using Cy2NLi in the presence of Mg, Zn or La halides in a continuous flow

21 January 2018

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New Syntheses of Diazo Compounds

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Modern Organic Synthesis with α-Diazocarbonyl Compounds.

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Diazo compounds in continuous-flow technology

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Taming hazardous chemistry in flow: the continuous processing of diazo and diazonium compounds

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Safe and Reliable Synthesis of Diazoketones and Quinoxalines in a Continuous Flow Reactor

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Development of a Continuous Process for the Industrial Generation of Diazomethane1

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Continuous in situ generation, separation, and reaction of diazomethane in a dual-channel microreactor.

21 January 2018

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Continuous flow generation and reactions of anhydrous diazomethane using a Teflon AF-2400 tube-in-tube reactor.

21 January 2018

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Flow ozonolysis using a semipermeable Teflon AF-2400 membrane to effect gas-liquid contact.

21 January 2018

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Continuous flow synthesis of α-halo ketones: essential building blocks of antiretroviral agents.

21 January 2018

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Cyclopropanation using flow-generated diazo compounds

21 January 2018

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A Versatile Room-Temperature Route to Di- and Trisubstituted Allenes Using Flow-Generated Diazo Compounds

21 January 2018

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Flow chemistry as a discovery tool to access sp2-sp3 cross-coupling reactions via diazo compounds.

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Iterative reactions of transient boronic acids enable sequential C-C bond formation

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Synthesis of β-keto esters in-flow and rapid access to substituted pyrimidines

21 January 2018

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Ethyl diazoacetate synthesis in flow

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On-chip generation and reaction of unstable intermediates-monolithic nanoreactors for diazonium chemistry: azo dyes

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Preparation of arylsulfonyl chlorides by chlorosulfonylation of in situ generated diazonium salts using a continuous flow reactor

21 January 2018

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Continuous-flow synthesis of monoarylated acetaldehydes using aryldiazonium salts.

21 January 2018

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A fully automated, multistep flow synthesis of 5-amino-4-cyano-1,2,3-triazoles

21 January 2018

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Multistep flow synthesis of 5-amino-2-aryl-2H-[1,2,3]-triazole-4-carbonitriles

21 January 2018

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Synthesis of 5-substituted 1H-tetrazoles from nitriles and hydrazoic acid by using a safe and scalable high-temperature microreactor approach.

21 January 2018

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Controlling hazardous chemicals in microreactors: synthesis with iodine azide

21 January 2018

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Flow synthesis of organic azides and the multistep synthesis of imines and amines using a new monolithic triphenylphosphine reagent

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Solvent- and catalyst-free huisgen cycloaddition to rufinamide in flow with a greener, less expensive dipolarophile

21 January 2018

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Continuous flow nitration in miniaturized devices

21 January 2018

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Controlled autocatalytic nitration of phenol in a microreactor

21 January 2018

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Multicomponent Reactions with Isocyanides.

21 January 2018

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Elemental fluorine. Part 16. Versatile thin-film gas-liquid multi-channel microreactors for effective scale-out

21 January 2018

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Elemental fluorine. Part 18. Selective direct fluorination of 1,3-ketoesters and 1,3-diketones using gas/liquid microreactor technology

21 January 2018

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Continuous gas/liquid–liquid/liquid flow synthesis of 4-fluoropyrazole derivatives by selective direct fluorination

21 January 2018

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Fluorination reactions in microreactors

21 January 2018

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Development of fluorination methods using continuous-flow microreactors

21 January 2018

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The application of a monolithic triphenylphosphine reagent for conducting Appel reactions in flow microreactors

21 January 2018

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The application of a monolithic triphenylphosphine reagent for conducting Ramirez gem-dibromoolefination reactions in flow

21 January 2018

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Selective monoiodination of aromatic compounds with electrochemically generated I+ using micromixing

21 January 2018

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Oxidation of alcohols by “activated” dimethyl sulfoxide. a preparative, steric and mechanistic study

21 January 2018

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Flash chemistry extensively optimized: high-temperature Swern-Moffatt oxidation in an automated microreactor platform

21 January 2018

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Efficient amide bond formation through a rapid and strong activation of carboxylic acids in a microflow reactor

21 January 2018

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A machine-assisted flow synthesis of SR48692: a probe for the investigation of neurotensin receptor-1.

21 January 2018

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Bisoxazoline-functionalised enantioselective monolithic mini-flow-reactors: development of efficient processes from batch to flow conditions

21 January 2018

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Efficient enhancement of copper-pyridineoxazoline catalysts through immobilization and process design

21 January 2018

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Continuous flow asymmetric cyclopropanation reactions using Cu(i) complexes of Pc-L* ligands supported on silica as catalysts with carbon dioxide as a carrier

21 January 2018

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Scalable in Situ Diazomethane Generation in Continuous-Flow Reactors

21 January 2018

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Continuous-flow synthesis of an efficient methanofullerene acceptor for bulk-heterojunction solar cells

21 January 2018

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Making diazomethane accessible for R&D and industry: generation and direct conversion in a continuous micro-reactor set-up

21 January 2018

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Continuous Production of the Diazomethane PrecursorN-Methyl-N-nitroso-p-toluenesulfonamide: Batch Optimization and Transfer into a Microreactor Setup

21 January 2018

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21 January 2018

Identifiers

DOI

10.1039/C5CS00902B

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27453961%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

1 reference