Drinks Cocktails Our Best Triple Sec Cocktails By Food & Wine Editors Food & Wine Editors This is collaborative content from Food & Wine's team of experts, including staff, recipe developers, chefs, and contributors. Many of our galleries curate recipes or guides from a variety of sources which we credit throughout the content and at each link. Food & Wine's Editorial Guidelines Published on May 17, 2021 Close Photo: Antonis Achilleos So you have a bottle of triple sec hanging out on your bar cart. Maybe you bought it to make margaritas and now you want to figure out other uses for it. Maybe you just love this orange-flavored liqueur and want more ideas for how to incorporate it into cocktails. Either way, we've got what you need: Our best triple sec recipes, from spins on a traditional margarita to a lychee gimlet. 01 of 08 Lychee Gimlet © Tina Rupp Lime juice, lychee nectar, triple sec, and gin come together in this cocktail that's simultaneously tart and sweet. Get the Recipe 02 of 08 Blood Orange Margaritas © John Kernick Blood orange gives this Margarita a beautiful color and a boost in citrus-y flavor. Get the Recipe 03 of 08 Pab's Buck © Lucas Allen This strawberry cocktail gets an extra note of sourness thanks to the inclusion of apple cider vinegar. Get the Recipe 04 of 08 Charred Citrus Margarita Antonis Achilleos Throwing slices of tangerines, grapefruit, and oranges on the grill gives this margarita an extra layer of smokey complexity. Get the Recipe 05 of 08 Sangria Flora © Wendell Webber A quarter cup of triple sec adds to the juicy, fruity vibe of this playful sangria. Get the Recipe 06 of 08 Cosmopolitan A 2000s-era classic, this cranberry and vodka drink adds a splash of triple sec and lime juice for a tart twist. Get the Recipe 07 of 08 Mediterranean Pink Lady © Tina Rupp Limoncello, dry gin, and Campari round out this crisp, unfussy but elegant cocktail. Get the Recipe 08 of 08 Combier Margarita © Wendell T. Webber Like Cointreau, Combier is a kind of triple sec used by bartenders to add a smooth orange flavor to cocktails. This margarita uses Combier, but you can swap in any triple sec you have on hand. Get the Recipe Was this page helpful? Thanks for your feedback! Tell us why! Other Submit