Anti Mullerian Hormone (AMH) Test

AMH Test is done for :

• Evaluating ovarian reserve and responsiveness for infertility and assisted reproduction.
• Checking menopausal state, including early ovarian failure.
• Assessing infants with ambiguous genitalia and other intersex conditions.
• Assessing testicular function in males.
• Monitoring patients with antimullerian hormone-secreting ovarian granulosa cell tumours.
• Diagnosing menstrual disorders in women, such as PCOS.
• Assessing the cause of amenorrhea in girls older than 15 years or women with no periods for several months at a stretch

AMH test measures Anti-Müllerian Hormone (AMH) levels in serum.

AMH test requires a blood sample. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in vacutainer.

• Menopausal women or women with premature ovarian failure of any cause, including after cancer chemotherapy, have very low anti-mullerian hormone (AMH) levels.
• AMH may be used as a surrogate to antral follicle count (AFC) at day 2 to 4 of the menstrual cycle to determine ovarian reserve.
• Women with an AFC greater than 15 are identified as having high ovarian reserve. 
• Values are high in women with PCOS.

The normal serum AMH level ranges between 2 and 6.8 ng/mL. A high level of AMH may be suggestive of PCOS. A low level of AMH may suggest:

1. The woman has a low ovarian reserve and may have difficulty conceiving.
2. The onset of menopause.
3. Women with premature ovarian failure on chemotherapy.
4. Low levels of AMH in male infants may indicate some genetic or hormonal issue, which can result in indistinguishable female or male genitalia.

On days 2 to 4 of the menstrual cycle, AMH levels can be used as a substitute for antral follicle count (AFC) to determine ovarian reserve. AMH values ranging from 2.19 to 4 indicate an AFC of 11-25. Women with an AFC of 15 or higher have a large ovarian reserve.

Along with the AMH test, a transvaginal ultrasound and hormone tests like estradiol and follicle-stimulating hormone (FSH) levels are often ordered. 

No special preparation, such as fasting, is required before the AMH test. However, it's important to consult with your healthcare provider before undergoing the test for any instructions.

On average, the AMH test costs between INR 1300 and 2750, depending on the lab.

The AMH test helps determine the fertility of a woman by estimating the number of egg cells she has. High AMH values mean there are more egg cells, and the woman has a high chance of conceiving. The AMH test aids in determining the success rate of assisted reproductive techniques such as in-vitro fertilisation in women seeking fertility treatment. 

Ambiguous genitalia is a congenital defect in which a baby's external genitalia do not have the typical appearance of male or female genitalia. In such cases, an AMH test along with genetic testing may be recommended to get more clarity about the infant's gender.

• Antimullerian Hormone
• Mullerian-inhibiting hormone (MIH)
• Mullerian inhibiting factor (MIF)
• Mullerian-inhibiting substance (MIS)

AMH test may be recommended for the following purposes:

• Difficulty conceiving.
• Determining success rate of fertility treatments such as in-vitro fertilisation (IVF).
• Showing symptoms of PCOS.
• Monitoring the effectiveness of ovarian cancer treatment.

The AMH test is a blood test that measures the level of anti-mullerian hormone in the blood, providing a snapshot of a woman's reproductive health and the number of remaining eggs in her ovaries

The anti-mullerian hormone test (AMH test) is important for evaluating ovarian reserve, predicting response to fertility treatments, diagnosing menstrual disorders, and monitoring ovarian cancers. It provides valuable insights for making informed choices about future pregnancies and fertility options.

A good anti-mullerian hormone level for conception is typically considered to be above 1.0 ng/mL. Levels between 1.0 and 3.5 ng/mL are commonly associated with a positive response to IVF stimulation and a healthy egg reserve.

The AMH test can be done at any point during the menstrual cycle since AMH levels do not fluctuate significantly throughout the month.

The AMH blood test provides benefits such as assessing ovarian reserve, predicting how one might respond to fertility treatments, diagnosing menstrual disorders and ovarian cancers, and plan for planning of future pregnancies and fertility treatments like IVF and egg freezing. 

An anti-mullerian hormone level of 0.2 ng/mL indicates a very low ovarian reserve, suggesting significantly reduced chances of natural conception or a successful IVF. While pregnancy isn't completely ruled out, fertility treatments are likely be more challenging. 

There is no direct evidence that stress lowers anti-mullerian hormone levels. Factors like age, genetic conditions, endometriosis, autoimmune diseases, and certain environmental exposures primarily influence AMH levels. 

Currently, there are no proven methods to increase anti-mullerian hormone levels. While lifestyle changes and minimising an exposure to certain environmental toxins may support overall ovarian health, they do not directly boost AMH levels. 

No, fasting is not required before taking the AMH test, and it can be done at any time. It's crucial to notify your doctor about any use of oral contraceptives, as they might influence the results. 

There is no specific age limit for the AMH test, but it is most relevant for women of reproductive age. AMH levels naturally decline with age and become undetectable at menopause. 

For a woman aged 35, an AMH level above 1.0 ng/mL is generally considered good, though levels can vary widely. Results should be interpreted in the context of overall reproductive health and other diagnostic tests.

Yes, some diagnostic centres and healthcare providers, like Metropolis Healthcare, offer the convenience of home sample collection for the AMH test. However, it is recommended to consult a healthcare professional for proper interpretation of the results. 

AMH test reports typically take 6 hours to be processed, though this can vary based on when the sample is collected and processed.