Cefoxim 1.5gm Injection 1's

INTRODUCTION ABOUT CEFOXIM 1.5GM INJECTION

CEFOXIM 1.5GM INJECTION is an antibiotic medicine used in the management of various bacterial infections such as infections of the respiratory tract, throat infections, skin infections, ear infections, sinus infections, lung infections, urinary tract infections, gynecological infections, blood infections, etc. It can also be used as a prophylactic therapy for reducing infection risks post-surgery.

It contains a medicine called Cefuroxime which is a powerful antibiotic agent that works by killing the susceptible organism that causes infection.

CEFOXIM 1.5GM INJECTION should be used under medical supervision. Usually, it is prescribed for 7-10 days to attain better control on infection. Therefore, do not stop taking this medicine or skip doses, as it may make this medicine less effective.

Before receiving CEFOXIM 1.5GM INJECTION, inform your doctor if you have kidney problems. You must also inform your doctor if you are allergic to any antibiotics, have fungal infections, previously experienced anaemia or diarrhoea after taking antibiotics, scheduled for any blood tests, or if you are pregnant or breastfeeding.

The most common side effect of receiving this medicine is pain at the injection site, swelling and redness. Consult your doctor immediately if any of the above symptoms worsen.

USES OF CEFOXIM 1.5GM INJECTION

CEFOXIM 1.5GM INJECTION is used in the management of severe bacterial infections such as:

• Respiratory tract infections (such as bronchitis, infected bronchiectasis, bacterial pneumonia)
• Ear, nose and throat infections (such as sinusitis, tonsillitis, pharyngitis and otitis media)
• Urinary tract infections
• Skin and soft tissue infections, Wound infections
• Bone and joint infections
• Gynaecological infections
• Blood infections
• Infection of outer covering of the brain
• Post surgical infections

HOW CEFOXIM 1.5GM INJECTION WORKS

CEFOXIM 1.5GM INJECTION contains Cefuroxime which is a second-generation cephalosporin that interferes with the synthesis of the bacterial cell wall by binding to specific binding proteins located inside the bacterial cell wall. This leads to breaking down the cell wall of the bacteria and reducing its stability, thus causing cell damage, and eventually causing bacterial elimination.

DIRECTIONS FOR USE

CEFOXIM 1.5GM INJECTION will be given to you only by a doctor or nurse by intramuscularly (into a muscle) or intravenously (into the vein). Your doctor will administer the correct dose for you depending upon your age, body weight and severity of infection.

SIDE EFFECTS OF CEFOXIM 1.5GM INJECTION

Common Side Effects of CEFOXIM 1.5GM INJECTION:

• pain (injection site), swelling and redness along a vein
• increase in liver enzyme
• changes in white blood cells (neutropenia or eosinophilia)
• low levels of red blood cells (anemia)
• high temperature
• sore throat

• skin rashes, urticaria (itchy red wheals), pruritus (bumpy rash)
• gastrointestinal disturbances
• diarrhoea, nausea
• increase in bilirubin (a substance produced by the liver)
• positive coomb’s test

Stop receiving CEFOXIM 1.5GM INJECTION and consult your doctor immediately if you experience any of the following side effects

• fungal infections
• severe diarrhoea (Pseudomembranous colitis), causing severe diarrhoea, usually with blood and mucus, stomach pain, and fever

WARNING & PRECAUTIONS

PREGNANCY

Consult your doctor

The safety of Cefuroxime during pregnancy has not been clearly established. Therefore, your doctor will advise you to use CEFOXIM 1.5GM INJECTION after analysing the risks and benefits of the therapy.

BREASTFEEDING

Use with Caution

CEFOXIM 1.5GM INJECTION should be used with caution during breastfeeding as it may pass into the breast milk.

DRIVING AND USING MACHINES

Use with Caution

Do not drive or operate heavy machines if you feel dizziness after receiving CEFOXIM 1.5GM INJECTION.

KIDNEY

Use with Caution

CEFOXIM 1.5GM INJECTION should be used with caution in patients with a history of kidney problems.

LIVER

Use with Caution

CEFOXIM 1.5GM INJECTION should be used with caution in patients with a history of liver problems.

ALLERGY

Contraindicated

Do not receive CEFOXIM 1.5GM INJECTION if you are allergic (hypersensitive) to Cefuroxime, cephalosporin, penicillin, monobactams, carbapenems or to any other ingredients of this medicine.

USE IN PEDIATRICS

Contraindicated

CEFOXIM 1.5GM INJECTION should be used in children aged below 18 years only if advised by the physician. Your doctor will administer the right dose depends on your child’s age, body weight and severity of the infection.

USE IN GERIATRICS

Use with Caution

CEFOXIM 1.5GM INJECTION should be used with caution in elderly patients suffering kidney problems. Consult your doctor before receiving.

INTERACTIONS

A. Drug-Drug interactions:

Before receiving CEFOXIM 1.5GM INJECTION, inform your doctor if you are receiving any of the following medicine:

• Other antibiotics (Ex. gentamycin)
• Diuretics (Ex. furosemide)
• Anti-gout agents (Ex. probenecid)
• Oral anticoagulants (Ex. warfarin)
• Birth control pills (Ex. ethinyl estradiol)

Overdosage:

It is unlikely to receive overdose since it will be administered by the doctor or nurse. If you experience any unusual side effects, consult your doctor immediately.

SYNOPSIS

MORE INFORMATION

FAQs ABOUT CEFOXIM 1.5GM INJECTION

REFERENCES

1. KD Tripathi. Beta-Lactam Antibiotics. Essentials of Medical Pharmacology. Seventh Edition,2013. Page - 727.  

2. Gold B, Rodriguez WJ. Cefuroxime: mechanisms of action, antimicrobial activity, pharmacokinetics, clinical applications, adverse reactions and therapeutic indications. National Library of Medicine. PubMed Central (PMC). [Accessed on 7th September 2022] click here

3. GlaxoSmithKline Manufacturing S.P.A. [Revised in July 2014] [Accessed on 7th September 2022] click here

4. Acs Dobfar S.P.A. The Electronic Medicines Compendium (Emc). [Revised in May 2022] [Accessed on 7th September 2022] click here

5. Villerton Invest SA. The Electronic Medicines Compendium (emc). [Revised in May 2021] [Accessed on 7th September 2022] click here

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6. Hikma Pharmaceuticals USA Inc. [Revised in May 2021] [Accessed on 7th September 2022] click here

7. Acs Dobfar Spa. [Revised in May 2021] [Accessed on 7th September 2022] click here

USEFUL DIAGNOSTIC TESTS

• Complete Blood Count (CBC)

AUTHOR DETAILS

Written By Srilekha. R - B.Pharm

Reviewed By Dr. Sankara Babu Gorle - MBBS, MD(Pharmacology) View profile

Last updated on 23 Nov 2024 | 04:55 PM(IST)