Chromosomes, Homologous Pairs, Chromatids and DNA Molecules Golden Rule

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Chromosomes, homologous pairs, chromatids and DNA molecules

Golden Rule:
1 DNA Molecule per 1 Chromatid

Chromatid
Duplicated Chromosome
Non-duplicated
chromosome
Dr. Sokolove
(per autosomal cell in
metaphase)

# DNA Molecules
1
2
1
92

G1
G0
S
G2
Mitosis
Cytokinesis
Meiosis I
Meiosis II
Right after Meiosis
II (cytokinesis)

# Chromosomes
2n
2n
2n
2n
2n
2n
2n
n

# DNA Molecules
2n
2n
4n
4n
4n
2n
4n
2n

How to figure out how many DNA molecules are present:


OR for non-duplicated (a.k.a. unreplicated) chromosomes:

Chromosomes, homologous pairs, chromatids and DNA molecules


Each number corresponds to an unreplicated homologous pair of chromosomes

Each number corresponds to a replicated homologous pair of chromosomes

Whats the difference between sister chromatids and homologous chromosomes?


Sister chromatids are (mostly) identical! Its basically a copy (replicate) of the original chromatid.
Homologous chromosomes only share the same size and shape they may contain the same genes, but they
may or may not be the same version in each chromosome of the pair. One comes from the father and one
from the mother. Crossing over occurs between these (NOT between sister chromatids).

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