Mark William Tibbitt, PH.D.: Curriculum Vitae
Mark William Tibbitt, PH.D.: Curriculum Vitae
Mark William Tibbitt, PH.D.: Curriculum Vitae
Contact
Phone: 720-951-7217
E-mail: [email protected]
Website: www.marktibbitt.com
June 2007
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Curriculum Vitae
21. Patel, A.K.; Tibbitt, M.W.; Celiz, A.D.; Langer, R.; Davies, M.C.; Denning, C.; Alexander, M.R.; Anderson, D.G. High
throughput screening for discovery of materials that control stem cell fate, Current Opinion in Solid State and Materials
Science, 2016, in press.
20. Tibbitt, M.W.; Dahlman, J.E.; Langer, R. Emerging frontiers in drug delivery, Journal of the American Chemical Society, 2016, 138, 704-717.
19. Tibbitt, M.W.*; Rodell, C.B.*; Burdick, J.A.; Anseth, K.S. Progress in material design for biomedical applications,
Proceedings of the National Academies of Science, 2015, 112, 14444-14451.
18. Appel, E.A.; Tibbitt, M.W.; Greer, J.M.; Fenton, O.S.; Kreuels, K.; Anderson, D.G.; Langer, R. Exploiting electrostatic
interactions in polymer-nanoparticle hydrogels, ACS Macro Letters, 2015, 4, 848-852.
17. Lewis, K.J.; Tibbitt, M.W.; Zhao, Y.; Branchfield, K.; Sun, X.; Balasubramaniam, V.; Anseth, K.S. In vitro model alveoli
from photodegradable microsphere templates, Biomaterials Science, 2015, 3, 821-832. (Front cover)
16. Appel, E.A.*; Tibbitt, M.W.*; Webber, M.J.; Mattix, B.A.; Veiseh, O.; Langer, R. Self-assembled hydrogels utilizing
polymer-nanoparticle interactions, Nature Communications, 2015, 6, #6295.
15. Yang, C.*; Tibbitt, M.W.*; Basta, L.; Anseth K.S. Reversible and irreversible effects of mechanical dosing on stem cell
fate, Nature Materials, 2014, 13, 645-652.
14. Wang, H.; Tibbitt, M.W.; Langer, S.; Leinwand, L.A.; Anseth, K.S. Hydrogels preserve native phenotypes of valvular
fibroblasts through an elasticity-regulated PI3K/AKT pathway, Proceedings of the National Academies of Science, 2013,
110, 19336-19341.
13. Tibbitt, M.W.; Sawicki, L.A.; Kloxin, A.M.; Anseth, K.S. Characterization of material properties and photodegradation in chain and step polymerized hydrogels, Macromolecules, 2013, 46, 2785-2792.
12. Shenoy, R.; Tibbitt, M.W.; Anseth, K.S.; Bowman, C.N. Formation of core-shell particles by interfacial radical polymerization initiated by a glucose oxidase-mediated redox system, Chemistry of Materials, 2013, 25, 761-767.
11. Tibbitt, M.W.; Kloxin, A.M.; Anseth, K.S. Modeling photodegradation in thick polymer networks for the predictable
control of network evolution, Journal of Polymer Science Part A: Polymer Chemistry, 2013, 51, 1899-1911. (Spotlight article)
10. Tibbitt, M.W.; Anseth, K.S. Dynamic microenvironments: the fourth dimension, Science Translational Medicine, 2012,
14, 160ps24. (Front cover)
9. Kloxin, A.M.; Lewis, K.J.; DeForest, C.A.; Seersdorf, G.; Tibbitt, M.W., Balasubramaniam, V.; Anseth K.S. Responsive culture platform to examine the influence of microenvironment geometry on cell function, Integrative Biology,
2012, 4, 1540-1549.
8. Guo, Q.; Wang, X.; Tibbitt, M.W.; Anseth K.S.; Montell, D.; Elisseeff, J.H. Light activated cell migration in synthetic
extracellular matrices, Biomaterials, 2012, 33, 8040-8046.
7. Azargarsamy, M.A.; Alge, D.L.; Radakrishnan, S.J.; Tibbitt, M.W.; Anseth K.S. Photocontrolled nanoparticles for
on-demand release of proteins, Biomacromolecules, 2012, 13, 2219-2224.
6. Tibbitt, M.W.; Han, B.W.; Kloxin, A.M.; Anseth, K.S. Synthesis and application of photodegradable microparticles
for spatiotemporal control of protein delivery, Journal of Biomedical Materials Research Part A, 2012, 100A, 1647-1654.
Student award for outstanding research Ph.D. category, 9th World Biomaterials Congress; Chengdu, China.
5. Kloxin, A.M.; Tibbitt, M.W.; Anseth, K.S. Synthesis of photodegradable hydrogels as dynamically tunable materials
for 2D and 3D cell culture, Nature Protocols, 2010, 5, 1867-1887.
4. Tibbitt, M.W.; Kloxin, A.M.; Dyamenahalli, K.U.; Anseth, K.S. Controlled two-photon photo degradation of PEG
hydrogels to study and manipulate sub cellular interactions on soft materials, Soft Matter, 2010, 6, 5100-5108.
3. Kloxin, A.M.; Tibbitt, M.W.; Kasko, A.M.; Fairbairn, J.; Anseth K.S. Controlled degradation of photolabile PEGbased hydrogels, Advanced Materials, 2010, 22, 61-66.
2. Tibbitt, M.W.; Anseth, K.S. Hydrogels as extracellular mimics for 3D cell culture, Biotechnology and Bioengineering,
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Curriculum Vitae
Book chapters:
1. Tibbitt, M.W.; Shadish, J.; DeForest, C.A. Photopolymers in biomaterials and hydrogels, In: Ovsianikov, A.;
Stampfl, J.; Liska, R. (Eds.) Nano- and microstructuring using multiphoton lithography. 2015, in press.
Patents:
3. Appel, E.A.; Tibbitt, M.W.; Langer, R. Biodegradable shear-thinning injectable hydrogels Submitted
2. Tibbitt, M.W.; Anseth, K.S.; Kloxin, A.M.; Toner, M.; Oakey, J.; Shah, A. Selective capture and release of rare mammalian cells using photodegradable hydrogels in a microfluidic platform WO2015010019A1
1. Anseth, K.S.; Kasko, A.M.; Tibbitt, M.W.; Kloxin, A.M.; Sridhar, B. Photodegradable groups for tunable polymeric
materials US20140031285A1
INVITED SEMINARS
Responsive hydrogels for cell culture and drug delivery Tibbitt, M.W. Squishy Physics Seminar, Harvard University,
Cambridge, MA, Sept 2015.
Macromolecular engineering of responsive materials Tibbitt, M.W. MIT Koch Insitute, Cambridge, MA, April 2015.
Valve cell response to substrate stiffness: molecular pathways; Does stiffness beget stiffness, as MR begets MR? Tibbitt,
M.W. Leducq TransAtlantic Network, London, England, Dec 2013.
Fundamental characterization of photodegradable hydrogels: Spatiotemporal control of the cellular microenvironment
Tibbitt, M.W. Engineering Life 2013, Dresden, Germany, Sept 2013. (Award Lecture)
Photodegradable PEG-based hydrogels: Dynamic control of the cellular microenvironment Tibbitt, M.W. University of
Wyoming Department of Chemical and Petroleum Engineering, Laramie, WY, Dec 2012.
Curriculum Vitae
Anseth, K.S. American Chemical Society Annual Meeting, Indianapolis, IN, Sept 2013 (Award Lecture).
Click-based, MMP-degradable and photodegradable hydrogels for 3D cell culture and cell recovery Tibbitt, M.W.;
Anseth, K.S. American Institute of Chemical Engineering Annual Meeting, Pittsburgh, PA, Nov 2012 (Oral).
Photodegradable microspheres for spatiotemporal control of protein delivery Tibbitt, M.W.; Anseth, K.S. Society for
Biomaterial Annual Meeting, New Orleans, LA, Oct 2012 (Award Lecture).
Photodegradable microspheres for spatiotemporal control of protein delivery Tibbitt, M.W.; Han B.W.; Kloxin, A.M.;
Anseth K.S. 9th World Biomaterials Congress, Chengdu, Sichuan, China, June 2012 (Oral).
Photoresponsive PEG-based hydrogels: Precise and predictable tuning of the mechanical and biochemical nature of the
stem cell niche Tibbitt, M.W.; Anseth K.S. Excellence in Graduate Polymer Research Symposium at the American Chemical
Society Annual Meeting, San Diego, CA, March 2012 (Award Lecture).
Spatiotemporal control of cell-ECM interactions with photoactive PEG-based hydrogels Tibbitt, M.W.; Kloxin, A.M.;
Dyamenahalli, K.U.; Anseth, K.S. Howard Hughes Medical Institute Science Meeting, Ashburn, Virginia, May 2011 (Poster).
Two-photon irradiation of photo responsive hydrogels to control cell-material interactions Tibbitt, M.W.; Kloxin, A.M.;
Anseth K.S. 32nd Australasian Polymer Society Meeting, Coffs Harbour, New South Wales, Australia, Feb 2011 (Oral).
Spatiotemporal control of cell-ECM interactions with photoactive PEG-based hydrogels Tibbitt, M.W.; Kloxin, A.M.;
Dyamenahalli, K.U.; Anseth, K.S. Gordon Research Conference: Signal Transduction in Engineered Extracellular Matrices, Biddeford, ME, Jun 2010 (Oral and Poster).
Photodegradable hydrogels to investigate the effect of ECM mechanics on encapsulated cell function Tibbitt, M.W.;
Kloxin, A.M.; Anseth, K.S. CalTech Soft Materials Workshop, Pasadena, CA, Feb 2010 (Poster).
Photodegradable hydrogels to investigate the effect of network structure on encapsulated cell function Tibbitt, M.W.;
Kloxin, A.M.; Dyamenahalli, K.U.; Anseth, K.S. Materials Research Society Fall Meeting, Boston, MA, Dec 2009 (Oral).
Spatial patterning of structural properties in a photodegradable PEG-based hydrogel for cell culture Tibbitt, M.W.;
Kloxin, A.M.; Anseth, K.S. Society for Biomaterials Annual Meeting, San Antonio, TX, April 2009 (Oral).
PROFESSIONAL EXPERIENCE
Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology
Mar 2013 - current
Research Advisor: Prof. Robert S. Langer
- Synthesis and characterization of shear-thinning and self-healing nano-network for local drug delivery applications
- Design and implementation of drug-eluting annuloplasty ring to treat ischemic mitral regurgitation
Nanoly Bioscience, Inc., Co-Founder & CTO
May 2012 - current
- Polymeric nano shield for vaccine thermoprotection during vaccine delivery to the 3rd world
Intels Top Social Innovation; Dells Global Social Innovation Challenge Winner; Tech Awards Young Innovator;
Airbuss Materials and Manufacturing Award at Hello Tomorrow Challenge
Chemical & Biological Engineering, University of Colorado Boulder
Jan 2008 - Feb 2013
Research Advisor: Prof. Kristi S. Anseth
- Synthesis and quantitative characterization of phototunable hydrogel networks
- Develop prescriptive models of single or multi-photon effects on network properties
- Exploit user-tunable hydrogels to better understand stem cell mechanobiology and response to ECM dynamics
Holling Marine Laboratory, NOAA
Research Advisors: Dr. A. Fred Holland and Dr. Guy DiDonato
- Tracking of point source contaminants in tidal estuaries
- Collect and analyze water and soil samples for pollution quality
Physics and Astronomy, Northwestern University
Research Advisor: Prof. Fred A. Rasio
- Small N-body simulations of planetary formation and stability
- Develop code in FORTRAN and C++ to model stellar dust coalescence with a massive center
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Curriculum Vitae
Fall 2009
PROFESSIONAL SERVICE
NSF Biomaterials Workshop: Important Areas for Future Investment
- Attendee and contributing author to chapter on Cell-Material Interactions
Scientific Outreach and Academic Service:
- Lead Graduate Teaching Assistant, University of Colorado Boulder
- High School Honors Institute Mentor, University of Colorado Boulder
- Student Annual Research Symposium Organizing Committee, University of Colorado Boulder
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June 2012
2010 - 2012
2008 - 2011
2008 - 2010
Curriculum Vitae
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2007 - 2008
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