New England Journal Medicine: Leukotriene Antagonists As First-Line or Add-On Asthma-Controller Therapy
New England Journal Medicine: Leukotriene Antagonists As First-Line or Add-On Asthma-Controller Therapy
New England Journal Medicine: Leukotriene Antagonists As First-Line or Add-On Asthma-Controller Therapy
journal of medicine
Leukotriene Antagonists as First-Line or
Add-on Asthma-Controller Therapy
David Price, F.R.C.G.P., Stanley D. Musgrave, M.D., Lee Shepstone, Ph.D., Elizabeth V. Hillyer,
D.V.M., Erika J. Sims, Ph.D., Richard F.T. Gilbert, M.R.C.G.P., Elizabeth F. Juniper, M.C.S.P.,
M.Sc., Jon G. Ayres, M.D., Linda Kemp, B.Sc., Annie Blyth, M.A., Edward C.F. Wilson, M.Sc.,
Stephanie Wolfe, M.Sc., R.G.N., Daryl Freeman, M.R.C.G.P., H. Miranda Mugford, Ph.D.,
Jamie Murdoch, Ph.D., and Ian Harvey, F.R.C.P.
William W. Busse, M.D., Wayne J. Morgan, M.D., C.M., Peter J. Gergen, M.D., M.P.H., Herman
E. Mitchell, Ph.D., James E. Gern, M.D., Andrew H. Liu, M.D., Rebecca S. Gruchalla, M.D.,
Ph.D., Meyer Kattan, M.D., C.M., Stephen J. Teach, M.D., M.P.H., Jacqueline A. Pongracic,
M.D., James F. Chmiel, M.D., M.P.H., Suzanne F. Steinbach, M.D., Agustin Calatroni, M.S.,
Alkis Togias, M.D., Katherine M. Thompson, R.N., M.S.N., Stanley J. Szefler, M.D., and
Christine A. Sorkness, Pharm.D.
Stephen P. Peters, M.D., Ph.D., Susan J. Kunselman, M.A., Nikolina Icitovic, M.A.S., Wendy C.
Moore, M.D., Rodolfo Pascual, M.D., Bill T. Ameredes, Ph.D., Homer A. Boushey, M.D.,
William J. Calhoun, M.D., Mario Castro, M.D., Reuben M. Cherniack, M.D., Timothy Craig,
D.O., Loren Denlinger, M.D., Ph.D., Linda L. Engle, B.S., Emily A. DiMango, M.D., John V.
Fahy, M.D., Elliot Israel, M.D., Nizar Jarjour, M.D., Shamsah D. Kazani, M.D., Monica Kraft,
M.D., Stephen C. Lazarus, M.D., Robert F. Lemanske, Jr., M.D., Njira Lugogo, M.D., Richard J.
Martin, M.D., Deborah A. Meyers, Ph.D., Joe Ramsdell, M.D., Christine A. Sorkness, Pharm.D.,
E. Rand Sutherland, M.D., Stanley J. Szefler, M.D., Stephen I. Wasserman, M.D., Michael J.
Walter, M.D., Michael E. Wechsler, M.D., Vernon M. Chinchilli, Ph.D., and Eugene R. Bleecker,
M.D. for the National Heart, Lung, and Blood Institute Asthma Clinical Research Network N
Engl J Med 2010; 363:1715-1726October 28, 2010
Original Article
Robert F. Lemanske, Jr., M.D., David T. Mauger, Ph.D., Christine A. Sorkness, Pharm.D., Daniel
J. Jackson, M.D., Susan J. Boehmer, M.S., Fernando D. Martinez, M.D., Robert C. Strunk, M.D.,
Stanley J. Szefler, M.D., Robert S. Zeiger, M.D., Ph.D., Leonard B. Bacharier, M.D., Ronina A.
Covar, M.D., Theresa W. Guilbert, M.D., Gary Larsen, M.D., Wayne J. Morgan, M.D., Mark H.
Moss, M.D., Joseph D. Spahn, M.D., and Lynn M. Taussig, M.D. for the Childhood Asthma
Research and Education (CARE) Network of the National Heart, Lung, and Blood Institute
Original Article
Patrick M.A. Sleiman, Ph.D., James Flory, Ph.D., Marcin Imielinski, M.D., Ph.D., Jonathan P.
Bradfield, B.S., Kiran Annaiah, M.Sc., Saffron A.G. Willis-Owen, Ph.D., Kai Wang, Ph.D.,
Nicholas M. Rafaels, M.S., Sven Michel, Ph.D., Klaus Bonnelykke, M.D., Ph.D., Haitao Zhang,
Ph.D., Cecilia E. Kim, B.A., Edward C. Frackelton, B.A., Joseph T. Glessner, M.Sc., Cuiping
Hou, M.Sc., F. George Otieno, M.Sc., Erin Santa, B.A., Kelly Thomas, B.A., Ryan M. Smith,
B.A., Wendy R. Glaberson, B.A., Maria Garris, B.A., Rosetta M. Chiavacci, B.S.N., Terri H.
Beaty, Ph.D., Ingo Ruczinski, Ph.D., Jordan M. Orange, M.D., Ph.D., Julian Allen, M.D.,
Jonathan M. Spergel, M.D., Ph.D., Robert Grundmeier, M.D., Ph.D., Rasika A. Mathias, Sc.D.,
Jason D. Christie, M.D., Erika von Mutius, M.D., William O.C. Cookson, M.D., Michael
Kabesch, M.D., Miriam F. Moffatt, Ph.D., Michael M. Grunstein, M.D., Ph.D., Kathleen C.
Barnes, Ph.D., Marcella Devoto, Ph.D., Mark Magnusson, M.D., Hongzhe Li, Ph.D., Struan F.A.
Grant, Ph.D., Hans Bisgaard, M.D., and Hakon Hakonarson, M.D., Ph.D.