Breast: Anatomy & Physiology

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BREAST

HISTORY & PE

ANATOMY & PHYSIOLOGY

Against the anterior thoracic cavity


Between the:
Clavicle and 2nd rib superiorly
6th rib inferiorly
Sternum medially
Mid-axillary laterally
Overlies 2 muscle:
Pectoralis major, superiorly
Serratus anterior, inferiorly
In describing clinical findings:
Divide the breast by quadrant
Explaining the location using time on the face of the clock
Distance by centimeters from nipple
Hormonally sensitive tissue
Consisting tissue:
Glandular tissue: secretory tubuloalveolar gland and ducts
Divided into 15-20 septated lobes
Drains into the milk-producing ducts (lactiferous gland) and
sinuses (lactiferous sinus/ampulla)
Opens up in the areola or nipple
Fibrous connective tissue: provides structural support
Fibrous bands and suspensory ligaments
Adipose tissue: predominant in the superficial and periphery area
Estrogen stimulate the growth of the mammary gland and the
deposition of fat to give mass to the breast
High estrogen state of pregnancy also completed the
development of glandular tissue production of milk
Final development into milk secreting organ also requires progesterone
Prolactin: enzyme promoting the milk secretion
Secretes by the anterior pituitary gland
Colostrums: fluid secreted during the last few days and 1st day after
parturition (birth of the baby)
Normal protein; no fat
Hypothalamic control: mainly inhibit prolactin
Prolactin inhibitory hormone (ex. Dopamine): secreted to
decrease the production of prolactin
Ejection process of milk production:
Oxytocin involves: posterior pituitary gland
Mechanism:
Suckling somatic impulses hypothalamus secretion of oxytocin &
prolactin
To the blood

Expressing milk to the alveoli Contraction of


myoepithelial cells
With +10-20 mmHg pressure

Flow of the milk

Tactile stimulation may cause:


Nipple smaller, firmer and more erect
Areola pucker and wrinkles
Physiologic condition
Areolar surface has small, rounded elevations:
Sebaceous gland
Sweat gland
Accessory areolar gland

CHANGES WITH AGING

Adolescence
Breast bud stage: elevation as a small mound, enlargement of
areolar diameter
Further enlargement of elevation with no separation of contours
Projection to form 2nd mound
Mature stage: projection of nipple only
Adult
Normal: soft, granular, nodular or lumpy
Uneven texture: physiologic nodularity bilateral
Nodularity may increase during premenstrual period may cause
tenderness
Aging
May atrophy and being replaced by fats
More flaccid & pendulous

LYMPHATICS
Central nodes: most frequently palpable
Lie along the chest wall
Inside the axilla apex
Midway between anterior and posterior axillary folds
Pectoral nodes
Anterior
Lower border of pectoralis major muscle
Inside the anterior axillary fold
Drains most of the breast and anterior chest wall
Subscapular nodes:
Posterior
Lateral border of scapula
Deep within the posterior axillary fold
Drains the posterior chest wall and a portion of the arm
Lateral nodes:
Along the upper humerus
Drains most of the arm
Supraclavicular & Infraclavicular
All 3 will drain to the central nodes and central nodes will drain to
these 2
Pectoral nodes may drain directly to these nodes

HEALTH HISTORY
Common questions:
Do you examine your breast?
How often?
When during your monthly cycle?
3 Common Concern:
Are there any lumps?
Are there any pain or discomfort?
Are there any discharge?
If yes, ask when it occurs? Spontaneous or after squeezing?
What color, consistency and quantity? Unilateral or
bilateral?

HEALTH PROMOTION & MAINTENANCE


PALPABLE MASSES OF THE BREAST Masses of the Breast
Age Common Lesion Characteristics
1525 Fibroadenoma Usually fine, round,
mobile, nontender
2550 1. Cysts Usually soft firm,
round, mobile, often
2. Fibrocystic tender
changes Nodular, ropelike

3. Cancer Delineated from


surrounding tissue
Over 50 Cancer -do-
Pregnancy/Lactation Lactating adenomas, cysts, mastitis, and cancer

Risk factor:
Age: are 50 y/o
Family history:
1st degree family (mother or sister) establish positive
family history
Highest risk: 1st degree family who premenopausal
with bilateral disease
25% probability
Mutation of BRCA1 & BRCA2 confer 50% risk for <50 y/o;
80% by 65 y/o
Highest risk: multiple relatives with breast cancer,
combined breast & ovarian cancer, bilateral cancer of
early onset of cancer
Menstrual & Pregnancy
Early menarche
Late menopause increase risk by
1st live birth after 35 2 3 fold
No pregnancy at all
Breast condition & diseases
Atypical hyperplasia 4.4% risk
Carcinoma in situ 6.9-12% risk
Screening:
Breast Self Examination (BSE): monthly after age of 20
Clinical Breast Examination (CBE):
Every 3 years 20-39 y/o
40 annually
Mammography: 40 annually

TECHNIQUE OF EXAMINATION
FEMALE BREAST
Enhance detection of mass that may be overlooked at the
mammograph
Demonstration of proper breast examination to the patient
Clinicians should:
Adopt systematic & thorough pattern
Varying palpitation pressure
Circular motion using finger pads
Standardized approach
Best time: 5-7 days after the onset of menstruation
Inspection:
Arms at Sides:
Appearance of the skin
Size and symmetry of the breast
Contour of the breast
Characteristics of nipples: size, shape, direction, rashes,
ulceration or discharge
Arms over head
Brings out dimpling and retraction otherwise invincible
Contour of the breast
Press hand against the hips
Contract the pectoral muscle
Brings out dimpling and retraction also
Contour of the breast
Leaning forward
For large and pendulous breast
Brings out dimpling and retraction also
Contour of the breast
Dimpling and retraction suggest underlying cancer
Palpation
Use the finger pads (usually 2nd, 3rd, and 4th digits)
Be systematic
Vertical strip pattern
Palpate in small, concentric circle
Lateral portion:
Roll unto opposite hip
Hand on forehead while keeping the shoulder pressing the
bed or examining table
Palpate from posterior axillary fold down to the bra-line
(infra-mammary fold), and medially until reaching the
nipple
Medial portion:
Hand at neck, lifting elbow until even with the shoulder,
shoulder pressing the bed or examining table
Palpate from nipple medially to the mid-sternal line, with
vertical strip pattern
Carefully examine:
Consistency
Tenderness
Nodules
Location
Size
Shape
Consistency
Tenderness
Mobility
Delimitation
Nipple: palpate elasticity
MALE BREAST
Inspect the nipple and areola: nodules, swelling or ulceration
Palpate for nodules
Gynecomastia: imbalance of estrogen and androgen production drugs
AXILLA
Inspection of the skin
Rash
Infection: sweat gland inflammation hydradenitis suppurativa
Unusual pigmentation: deeply pigmented(velvety) acanthosis
nigricans
Palpation: palpate the nodes
Center nodes: reach as high into the apex of the axilla, directly
behind pectoral muscle, pointing toward mid-clavicle. Press
toward chest wall and slide downward.
Pectoral nodes: grasp anterior axillary fold and feel inside the
border of pectoral muscle
Subscapular nodes: inside the muscle of posterior axillary fold
Lateral nodes: high in the axilla, along the upper humerus
SPECIAL TECHNIQUE
Spontaneous nipple discharge:
Compressing the areola with index finger in radial position to the
nipple.
Watch for discharge
Note: color, consistency, quantity, and exact location
Examination of mastectomy patient:
Inspect and palpate for any mass along the scar
Palpate for lymph nodes enlargement
Instruction for BSE

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