BLUEPRINT FOR QUESTIONS

PATHOLOGY
9. Increased susceptibility to infection in diabetic patients is due to:
MEAN MPL FOR THIS EXAM: 76.89 A. Deficiency of emigration and chemotaxis of neutrophils
CEBU INSTITUTE OF MEDICINE B. B cell deficiency
C. Impaired microbicidal activity
Department of Pathology D. Nitric oxide deficiency
(Answer: A/Reference: p. 55 / MPL 60)

NAME _________________________________ GROUP NO. ____ I.D. NO. ________ 10. Which is not associated with chronic inflammation?
A. Fibrosis C. Granuloma
DIRECTION: Each question below is followed by four possible answers. Select the one best response and mark the B. Neutrophilic infiltration D. Macrophages and epithelioid cells
appropriate spaces on the answer sheet provided for. (Answer: B/Reference: p. 79 / MPL 60)

1. The morphologic pattern of necrosis in myocardial infarction is : 11. Redness is:

A. Coagulative necrosis C. Fat necrosis A. Calor C. Dolor
B. Liquefactive necrosis D. Caseation necrosis B. Tumor D. None of these
(Answer: A/ Reference: p. 17 / MPL 90) (Answer: D/Reference: p. 50 / MPL 90)

2. The most common cause of fatty change in the liver is: 12. Brown atrophy of the heart in aging is due to:
A. CC14 poisoning C. Diabetes mellitus A. Amyloid deposits C. Hemosiderin pigments
B. Alcohol abuse D. Protein malnutrition B. Lipofuscin D. Basophilic degeneration
(Answer: B/Reference: p. 39 / MPL 90) (Answer: B p 26 /MPL 90 )

3. The cellular adaptation that occurs in the respiratory tract of a chronic cigarette smoker is: 13. 47, XXY is :
A. Hyperplasia C. Metaplasia A. Cri-du-chat syndrome C. Turner’s syndrome
B. Hypertrophy D. Atrophy B. Klinefelter’s syndrome D. Normal female
(Answer: C/Reference: p. 36 / MPL 90) (Answer: B p 170/MPL 60)

4. The first manifestation of almost all forms of cell injury is: 14. Tall stature and arachnodactyly are characteristic of:
A. Fatty change C. Dystrophic caicification A. Ehlers-Danlos syndrome C. Prader-Willi syndrome
B. Hyaline change D. Cellular swelling B. Trisomy 21 D. Marfan syndrome
(Answer: D/Reference: p. 7 / MPL 90) (Answer: D p 147 /MPL 90 )

5. Refers to the focal accumulation of cholesterol-laden macrophages in the lamina propia of 15. Transplant rejection is which type of hypersensitivity reaction?
the gallbladder: A. type I C. type III
A. Steatosis C. Xanthoma B. type II D. type IV
B. Cholesterolosis D. None of these (Answer: D p 206 /MPL 60 )
(Answer: D/Reference: p. 895 / MPL 90)
16. Which is NOT a major (Jones) criterion of rheumatic fever?
6. Which is granulomatous disease? A. Carditis C. arthralgia
A. Leprosy C. Tuberculosis B. erythema marginatum D. sydenham’s chorea
B. Schistosomiasis D All of these (Answer: C p 570 /MPL 90)
(Answer: D/Reference: p. 65 / MPL 90)
17. Thymic hypoplasia is a feature of:
7. Antipyretics inhibit inflammatory process by inhibiting: A. Sjogren’s syndrome C. Di George syndrome
A. Cyclooxygenase pathway C. Lipooxygenase pathway B. SLE D. Wiskott-Aldrich syndrome
B. Dismutase D. A & C (Answer: C p 173 /MPL 60 )
(Answer: A/Reference: p. 50 / MPL 33)
18. CREST syndrome is related to:
8. Chronic granulomatous disease is characterized by impaired microbicidal ability A. Hyper-IgM syndrome C. scleroderma, localized
due to: B. Bruton’s hypogammaglobulinemia D. preeclampsia
A. NADH oxidase deficiency C. Lack of adhesion molecules (Answer: C p 226 /MPL 33)
B. T cell immunodeficiency D. Complement deficiency
(Answer: A/Reference: p. 65 / MPL 33)

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 19. Which is not oncogenic? 30. Risk factors for atherosclerosis:
A. Human papilloma virus C. Herpes virus A. Cigarette smoking C. Diabetes
B. Hepatitis B virus D. Epstein-Barr virus B. Hypertension D. All of these
(Answer: C/Reference: p. 311 / MPL 60) (Answer: D p 498 /MPL 90 )

20. Which is not a malignant tumor? 31. Which typically presents with headache and facial pain?
A. Lymphoma C. Leiomyosarcoma A. Temporal arteritis C. Kawasaki disease
B. Melanoma D. Hamartoma B. Polyarteritis nodosa D. Takayasu arteritis
(Answer: D/Reference: p. 261 / MPL 90) (Answer: A p 516 /MPL 60)

21. Features of malignant cells, EXCEPT: 32. Rib-notching on chest x-ray is a finding in:
A. Hyperchromatic and pleomorphic nuclei C. Anaplasia A. Tetralogy of Fallot C. aortic coarctation
B. Tumor giant cell D. No exception B. Patent ductus arteriosus D. all of these
(Answer: D p 264/MPL 90) (Answer: C p 596 /MPL 90)

22. Leading type of cancer in men: 33. Mid-systolic click can be heard in:
A. skin cancer C. lung cancer A. Mitral valve prolapse C. Ventricular septal defect
B. prostate cancer D. testicular cancer B. Atrial septal defect D. Carcinoid heart disease
(Answer: B p 261 /MPL 60)23. (Answer: A p 568 /MPL 90 )

23. Which of the following refers to the degree of cellular differentiation of tumor 34 Coronary artery spasm is noted in:
cells? A. Stable angina C. unstable angina
A. Stage C. grade B. Prinzmetal angina D. All of these
B. Metastasis D. Doubling time (Answer: B p 554 /MPL 60)
(Answer: C p 261 /MPL 90)
35. Troponin rises after:
24. Warthin-finkeldey cells are seen in: A. Acute myocardial infarction C. Pancreatitis
A. Chicken pox C. herpes simplex infection B. Angina pectoris D. Liver necrosis
B. Mumps D. Measles (Answer: A p 561 /MPL 90)
(Answer: D p 370 /MPL 60)
36. Hemoglobin H disease is a variant of:
25. Ghon complex is associated with: A. Alpha-thalassemia C. Beta-thalassemia
A. Leprosy C. HIV infection B. Sickle cell disease D. Immunohemolytic anemia
B. Tuberculosis D. all of these (Answer: A p 619 /MPL 60)
(Answer: B p 723/MPL 90)
37. Hemolysis with antimalarial drug administration can occur in:
26. Ultraviolet rays are implicated in: A. Iron deficiency anemia C. mycosis fungoides
A. Gastric cancer C. Squamous cell carcinoma, skin B. G6PD deficiency D. Pernicious anemia
B. Urinary bladder cancer D. Bronchogenic carcinoma (Answer: B p 610 /MPL 90)
(Answer: C p 310/MPL 90)
38. Pancytopenia is a feature of:
27. Trenchfoot is due to: A. Paroxysmal nocturnal hemoglobinuria C. Folate deficiency
A. Blast injury C. greenhouse effect B. Hereditary spherocytosis D. Aplastic anemia
B. Mercury poisoning D. Hypothermia (Answer: D p 630 /MPL 90)
(Answer: D p 435/MPL 90)
39. Which can lead to DIC?
28. The disease of the displaced child: A. Septic abortion C. Gram negative sepsis
A. Marasmus C. Keshan diseae B. Extensive surgery D. All of these
B. Kwashiorkor D. Bulimia (Answer: D p 640 /MPL 90)
(Answer: B p 437 /MPL 90 )
40. Which causes relative polycythemia?
29. Bends and chokes are features of: A. High-altitude living C. Gaisbock syndrome
A. Fat embolism C. air embolism B. Renal cell carcinoma D. Cyanotic heart disease
B. Paradoxic embolism D. amniotic fluid embolism (Answer: C p 633 /MPL 90)
(Answer: C p 131 /MPL 90)

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41. The most common cause of microcytic, hypochromic anemia is:
A. Vitamin B12 deficiency C. Pure red cell aplasia 52. Low levels of serum alpha-1 antitrypsin can cause:
B. Iron deficiency D. Leukemia A. Bronchiectasis C. Chronic bronchitis
(Answer:B p 627 /MPL 90 ) B. Emphysema D. All of these
(Answer: B p 707 /MPL 60)

42. Evaluates the intrinsic coagulation pathway and is most commonly used to 53. Intrinsic asthma is initiated by:
monitor heparin therapy: A. Pulmonary viral infection C. Inhaled irritants
A. Prothrombin time C. APTT B. Aspirin ingestion D. All of these
B. Bleeding time D. Clotting time (Answer: D p 707 /MPL 60)
(Answer: C p 633 /MPL 60)
54. True of adult respiratory distress syndrome, EXCEPT:
43. Defective platelet aggregation occur in: A. Diffuse alveolar capillary damage
A. Glanzmann’s thrombasthenia C. Bernard-Soulier syndrome B. Deficiency of pulmonary surfactant
B. Henoch-Schonlein purpura D. vonWillebrand disease C. Noncardiogenic pulmonary edema
(Answer: A p 122 /MPL 60) D. No exception
(Answer: B p 760 /MPL 60)
44. Which is not a cause of eosinophilic leukocytosis?
A. Allergic disorders C. Viral infection 55. Failure of involution of the vitelline duct leads to:
B. Parasitism D. drug reaction A. Herniation C. Meckel’s diverticulum
(Answer: C p 647 /MPL 90) B. Volvulus D. All of these
(Answer: C p 804 /MPL 90)
45. M spike on protein electrophoresis is noted in:
A. Multiple myeloma C. Hodgkin’s disease 56. One segment of the small intestine constricted by a wave of peristalsis suddenly
B. Burkitt’s lymphoma D. All of these became telescoped into the distal segment happen in:
(Answer: A p 664 /MPL60) A. Intussusception C. Volvulus
B. Diverticula D. Strangulation
46. Auer rods are diagnostic of: (Answer: A p 804 /MPL 90)
A. Acute myeloblastic leukemia C. Acute lymphoblastic leukemia
B. Chronic lymphocytic leukemia D. Chronic myelocytic leukemia 57. Absence of ganglion cells in the large bowel leading to functional obstruction
(Answer: A p 678 /MPL 90) with colonic dilatation:
A. Achalasia C. Hirschsprung disease
47. Reed-Sternberg cells are diagnostic of: B. Ulcerative colitis D. Angiodysplasia
A. non-Hodgkin’s lymphoma C. Myelodysplastic syndrome (Answer C: p 805 /MPL 90)
B. Polycythemia vera D. None of these
(Answer: D p 670 /MPL 90) 58. A portion of the abdominal wall fails to form altogether with extrusion of the
intestine:
48. Variants of Langerhans cell histiocytosis include the ff., EXCEPT: A. Omphalocele C. Meckel’s diverticulum
A. Eosinophilic granuloma C. Letterer-Siwe disease B. Herniation D. Gastroschisis
B. Myelofibrosis with myeloid metaplasia D. Hand-Schuller disease (Answer: D p 804 /MPL 60)
(Answer: B p 685 /MPL 60)
59. Complications of colonic diverticula, EXCEPT:
49. Cor pulmonale is associated with: A. Obstruction C. Bleeding
A. L-sided heart failure C. Both A & B B. Peritonitis D. Malignancy
B. R-sided heart failure D. Neither A nor B (Answer: D p 823 /MPL 60)
(Answer: B p 565 /MPL 60)
60. Causes of hematemesis, EXCEPT;
50. Presence of rheumatoid nodules and pneumoconiosis constitutes: A. Mallory-Weiss syndrome C. Peptic ulcer
A. Goodpasture’s syndrome C. Loeffler’s syndrome B. Esophageal Varices D. Barrett’s esophagus
B. Mickulicz syndrome D. Caplan syndrome (Answer: D p 783 /MPL 60)
(Answer: D p 729 /MPL 60)
61. Nutmeg liver is due to:
51. May produce pulmonary hypertension, EXCEPT: A. Inflammation C. congestion
A. Mitral stenosis C. Emphysema B. Neoplasm D. cirrhosis
B. Recurrent pulmonary emboli D. No exception (Answer: C p 117/MPL 90)
(Answer: D p 704 /MPL 60)
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 62. Bronze diabetes refers to: 73. Maturation index determination is done with:
A. Wilson’s disease C. Primary hemochromatosis A. Paps smear C. Tzanck smear
B. Budd-Chiari syndrome D. Reye’s syndrome B. Gram stain D. All of these
(Answer: C p 873 / MPL 60) (Answer: A p 322 / MPL 90)

63. There is conjugated hyperbilirubinemia in: 74. Orifice of the prepuce is too small to permit its normal retraction:
A. Dubin-Johnson’s syndrome C. Rotor’s syndrome A. Epispadias C. Paraphemosis
B. Gilbert’s syndrome D. A & C B. Chondyloma D. None of these
( Answer : D p 850 /MPL 90) (Answer: D p 1012 / MPL 60)

64. Most common predisposing cause of ascending cholangitis: 75. Positively identified as cause of the cancer of the cervix:
A. Acute pancreatitis C. Choledocholithiasis A. Cytomegalovirus C. Herpes virus
B. Benign stricture D. Tumors B. Candidiasis D. Human papilloma virus
(Answer: C p 879 /MPL 90) (Answer: D p 1012 /MPL 60)

65 . Rokitansky-Aschoff sinuses are seen in: 76. Features of toxemia of pregnancy, EXCEPT:
A. Rheumatic heart disease C. Biliary atresia A. Anemia C. Hypertension
B. Chronic Cholecytitis D. Criggler-Najjar syndrome B. Edema D. Proteinuria
(Answer: B p 892 /MPL 90) (Answer: A p 1082 / MPL 90)

66. Etiologic factors in acute pancreatitis include the ff., EXCEPT: 77. Hormone used to determine pregnancy:
A. Alcoholism C. Gall stones A. FSH C. Progesterone
B. Genetic D. No exception B. Beta-HCG D. All of these
(Answer: D p 904 /MPL 90) (Answer: B p 1079 / MPL 90)

67. Late complications of chronic pancreatitis include the ff., EXCEPT:\ 78. Not seen in secretory endometrium:
A. Diarrhea (Malabsorption) C. Diabetes A. Mitosis and gland proliferation C. Secretion
B. Pseudocyst D. Hemorrhage B. Subnuclear vacuole D. Prominent spiral arteriole
(Answer: D p 907 /MPL 90) (Answer: A p 1037 / MPL 90)

68. Azotemia, hypocalcemia and hyperparathyroidism are associated with: 79. The most common complication of gonorrhea in women:
A. Acute renal failure C. Nephretic syndrome A. Endometriosis C. Vulvovaginitis
B. Chronic renal failure D. Nephrotic syndrome B. Endometritis D. Pelvic inflammatory disease
(Answer: B p 935 /MPL 60) (Answer: D p 1017 / MPL 90)

69. Associated with Proteus infection, also called Staghorn calculi: 80. All are important in semen analysis, EXCEPT:
A. Calcium stones C. Struvite stones A. Sperm count C. Volume
B. Uric acid stones D. None of these B. Morphology D. Motility
(Answer: C p 989 /MPL 90) (Answer: C p 510 / MPL 90)

70. Which is not associated with diabetic nephropathy? 81. Most common site of endometriosis:
A. Kimmelsteil-Wilson disease C. Papillary necrosis A. Ovaries C. Peritonium
B. Acute pyelonephritis D. Renal artery stenosis B. Uterine ligament D. Rectovaginal septum
(Answer: D p 966 /MPL 60) (Answer:A p 1057 / MPL 90)

71. IgA deposit in mesangium can be appreciated by: 82. Clinical indicator of hyperestrinism:
A. Immunofluorescence microscopy C. Light microscopy A. Mastitis C. Nipple inversion
B. Electron microscopy D. All of these B. Fat necrosis D. Gynecomastia
(Answer: A p 961 /MPL 60) (Answer: D p 1117 / MPL 90)

72 .Nephritic factor, dense deposits are related to: 83. Morphologic patterns of fibrocystic change of the breast, EXCEPT:
A. Membranoproliferative glomerulonephritis A. Adenosis C. Fibrosis
B. Lipoid nephrosis B. Cyst formation D. Papilloma
C. Focal segmental glomerulonephritis (Answer: D p 1098 / MPL 90)
D. Acute post-streptococcal glomerulonephritis
(Answer: A p 958 /MPL 90)

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 84. Acquired retraction of the nipple occur in: 95. Calcium pyrophosphate deposition occur in:
A. Lactation C. Breast cancer A. Gout C. Pseudogout
B. Silicon breast implant D. All of these B. Rheumatoid arthritis D. All of these
(Answer: C p 1104 / MPL 90) (Answer: C p 1257 /MPL 90)

85. There is insulin resistance in: 96. Degenerative joint disease is:
A. Type 1 diabetes mellitus C. A & B A. Rheumatoid arthritis C. Gouty arthritis
B. Type 2 diabetes mellitus D Neither A nor B B. Marie-Strumpel disease D. Osteoarthritis
(Answer: B p 913 /MPL 9 ) (Answer: D p 1246 / MPL 90)

86. Ischemic necrosis of the anterior pituitary leads to: 97. Infection of CNS in neonate during delivery occur in which condition:
A. Cushing’s disease C. Sheehan syndrome A. Syphilis C. Gonorrhea
B. SIADH D. Cretinism B. Herpes simplex condition D. Chlamydial infection
(Answer: C p 642 /MPL 90) (Answer: B p 1318 / MPL 60)

87. Believe to be cause by viral infection or post viral inflammatory process: 98. CSF albuminucytologic dissociation occur in:
A. Subacute granulomatous thyroiditis C. Reidel thyroiditis A. Multiple sclerosis C. Guillain- Barre syndrome
B. Hashimoto’s thyroiditis D. All of these B. Pyogenic meningitis D. Subarachnoid hemorrhage
(Answer: A p 1135 / MPL 60) (Answer: C p 1275 / MPL 60)

88. Most frequent type of hyperfunctioning pituitary adenoma: 99. The counterpart of mad cow disease in human is:
A. Somatostatinoma C. Prolactinoma A. Creutzfetldt-Jacob disease C. Rabies
B. Corticotroph adenoma D. Thyrotroph adenoma B. Progressive multifocal leucoencephalopathy D. None of these
(Answer: C p 1123 / MPL 60) (Answer: C p 1323 / MPL 90 )

89. Chronic adrenal insufficiency leads to: 100. Gemistocytic astrocytes are noted in:
A. Waterhouse-Friederichsen syndrome C. Cushing’s syndrome A. Hypoglycemia C. Damaged brain
B. Addison’s disease D. Hyperaldosteronism B. Ethanol abuse D. All of these
(Answer: B p 1160 / MPL 90) (Answer: C p 1297 / MPL 60)

90. A cause of primary osteoporosis:

A. Post menopausal C. Malnutrition
B. Hyperparathyroidism D. Rheumatologic disease
(Answer: A p 1222 / MPL 90)

91. A genetic derangement in epiphysial cartillagenous growth resulting in dwarfism: References:

A. Osteogenesis imperfecta C. Achondroplasia
B. Osteopetrosis D. Paget’s disease 1. Robbin’s Pathologic Basis of Disease 6th Edition
(Answer: C p 1220 /MPL 60)
2. Henry’s Clinical Diagnosis and Management 19th Edition
92. Failure in bone mineralization resulting in exist unmineralize matrix and
abnormally wide osteioid seems occur in:
A. Rickets C. Osteomalasia
B. Ostitis deformans D. A & C
(Answer: D p 1227 / MPL 60)

93. Saber shin is due to:

A. Rickets C. Syphilis
B. Pyogenic osteomyelitis D. Pott’s disease
(Answer: C p 1233 / MPL 90)

94. Chronic tophaceous gout and arthritis occur in:

A. Hyperuresimia C. Hyperglycemia
B. Hypercalcemia D. Hyperproteinemia
(Answer: A p 1253 / MPL 60)