Cartalla, Sofia Millen B.

Drug Study – OB Ward

2018 – 00229
BSN 2 – 1
DRUG STUDY

GENERIC BRAND SPECIAL DRUG TO DRUG NURSING

DRUG NAME INDICATION SIDE EFFECTS
NAME NAME PRECAUTIONS INTERACTION CONSIDERATIONS

Oral
(cefuroxime CNS: Headache, ASSESSMENT:
axetil) dizziness, lethargy, History: Hepatic
Pharyngitis, paresthesias and renal
tonsillitis impairment,
GI: Nausea, vomiting, lactation, pregnancy
Otitis media diarrhea, anorexia, Physical: Skin
Increased abdominal pain, status, LFT’s, renal
Acute bacterial nephrotoxicity flatulence, function test, culture
maxillary with pseudomembranous of affected area,
sinusitis aminoglycosides colitis, hepatotoxicity sensitivity tests
Contraindicated
Lower with allergy to Increased bleeding GU: Nephrotoxicity TEACHING
respiratory cephalosporins effects Hematologic: Bone POINTS:
infections or penicillins. with oral marrow depression Take full course of
Cefuroxime Cefuroxime Ceftin anticoagulants (decreased WBC, therapy even if you
UTIs Use cautiously decreased platelets, are feeling better.
with renal failure, Risk of disulfiram- decreased Hct)
Uncomplicated lactation, like reaction with This drug is specific
gonorrhea pregnancy. alcohol; avoid this Hypersensitivity: for this infection and
(urethral and combination during Ranging from rash to should not be used
endocervical) and for 3 days fever to anaphylaxis; to self-treat other
after completion serum sickness problems.
Skin and skin of therapy reaction
structure Swallow tablets
infections, Local: Pain, abscess whole; do not crush
including at injection site, them. Take the drug
impetigo phlebitis, with food.
inflammation at IV
site
 Cartalla, Sofia Millen B. Drug Study – OB Ward
2018 – 00229
BSN 2 – 1
You may
Treatment of experience these
early Lyme Other: side effects:
disease Superinfections, Stomach upset or
disulfiram-like diarrhea.
reaction with alcohol
Report severe
diarrhea with blood,
pus, or mucus; rash;
difficulty breathing;
unusual tiredness,
fatigue; unusual
bleeding or bruising;
unusual itching or
irritation.

GENERIC BRAND SPECIAL DRUG TO DRUG NURSING

DRUG NAME INDICATION SIDE EFFECTS
NAME NAME PRECAUTIONS INTERACTION CONSIDERATIONS

Contraindicated
with Decreased ASSESSMENT:
Acute infection CNS: Headache,
hypersensitivity effectiveness with History: CNS or
with susceptible dizziness, ataxia,
to Barbiturates hepatic disease,
anaerobic vertigo,
metronidazole; candidiasis
bacteria incoordination,
pregnancy (do Disulfiram-like (moniliasis), blood
insomnia, seizures,
not use for reaction (flushing, dyscrasias,
Acute intestinal peripheral
trichomoniasis in tachycardia, pregnancy, lactation
Metroni- amebiasis neuropathy, fatigue
Metronidazole Flagyl first trimester). nausea, vomiting)
dazole
with Physical: Reflexes,
Amebic liver GI: Unpleasant
Use cautiously alcohol affect; abdominal
abscess metallic taste,
with CNS examination, liver
anorexia,
diseases, Psychosis if taken palpation,
Trichomoniasis nausea, vomiting,
hepatic with disulfiram urinalysis, CBC,
(acute and diarrhea, GI upset,
disease, LFTs
partners of cramps
candidiasis
patients
(moniliasis),
Cartalla, Sofia Millen B. Drug Study – OB Ward
2018 – 00229
BSN 2 – 1
with acute blood GU: Dysuria,
infection) dyscrasias, incontinence,
lactation. darkening of the urine
Increased bleeding TEACHING
tendencies with Local: POINTS:
Bacterial oral Thrombophlebitis Take full course of
vaginosis anticoagulants (IV); redness, drug therapy; take
burning, dryness, and the drug with food if
Preoperative, skin irritation GI upset occurs
intraoperative, (topical)
postoperative Do not drink alcohol
prophylaxis for Other: Severe, (beverages or
patients disulfiram-like preparations
undergoing interaction containing alcohol,
colorectal with alcohol, cough syrups) for
surgery candidiasis 24-72 hr of drug
(superinfection) use; severe
reactions may
occur.

Urine may be a
darker color than
usual; this is
expected.

Patient may
experience these
side effects: Dry
mouth with strange
metallic taste
(frequent mouth
care, sucking
sugarless candies
may help); nausea,
vomiting, diarrhea
(eat frequent
 Cartalla, Sofia Millen B. Drug Study – OB Ward
2018 – 00229
BSN 2 – 1
small meals).

Report severe GI
upset, dizziness,
unusual fatigue or
weakness, fever,
chills.

GENERIC BRAND SPECIAL DRUG TO DRUG NURSING

DRUG NAME INDICATION SIDE EFFECTS
NAME NAME PRECAUTIONS INTERACTION CONSIDERATIONS

Contraindicated
with hyper- CNS: Headache, ASSESSMENT:
sensitivity to dizziness, History: Allergies;
mefenamic acid, somnolence, renal, hepatic, CV,
aspirin or NSAID insomnia, fatigue, GI conditions;
allergy, and as tiredness, dizziness, pregnancy; lactation
treatment of tinnitus,
Relief of perioperative ophthalmic effects Physical: Skin
moderate pain pain with color and lesions;
when therapy coronary artery Increased risk of Dermatologic: Rash, orientation,
will not exceed bypass grafting. GI bleeds pruritus, sweating, reflexes,
Mefenamic Mefenamic
Ponstan 1 week with ASA, dry mucous ophthalmologic and
Acid Acid
Use cautiously anticoagulants, membranes, audiometric
Treatment of with asthma, other NSAIDs stomatitis evaluation,
primary renal or hepatic peripheral
dysmenorrhea impairment, GI: Nausea, sensation; liver
peptic ulcer dyspepsia, GI pain, evaluation; CBC,
disease, GI diarrhea, clotting times, LFTs,
bleeding, vomiting, renal function tests;
hypertension, constipation, serum electrolytes
heart failure, flatulence, ulcers,
pregnancy, GI bleed
lactation.
Cartalla, Sofia Millen B. Drug Study – OB Ward
2018 – 00229
BSN 2 – 1
GU: Dysuria, renal TEACHING
impairment POINTS:
Take drug with
food; take only the
prescribed dosage;
Hematologic: do not take the drug
Bleeding, platelet longer than 1 week.
inhibition Discontinue drug
with higher doses, and consult your
neutropenia, health care provider
eosinophilia, if rash, diarrhea, or
leukopenia, digestive problems
pancytopenia, occur.
thrombocytopenia,
agranulocytosis, Dizziness or
granulocytopenia, drowsiness can
occur (avoid
driving and using
dangerous
machinery).

Report sore throat,

fever, rash, itching,
weight gain,
swelling in ankles or
fingers; changes in
vision; black, tarry
stools; severe
diarrhea, right upper
abdominal pain,
flulike symptoms,
chest pain
 Cartalla, Sofia Millen B. Drug Study – OB Ward
2018 – 00229
BSN 2 – 1

GENERIC BRAND SPECIAL DRUG TO DRUG NURSING

DRUG NAME INDICATION SIDE EFFECTS
NAME NAME PRECAUTIONS INTERACTION CONSIDERATIONS

ASSESSMENT:
Increased risk of
History: Allergy to
hypoglycaemia
methenamine,
with insulin and
tartrazine, aspirin;
insulin
Contraindicated renal or hepatic
secretagogues
with allergy to Dermatologic: impairment;
(e.g. sulfonylurea).
methenamine, Pruritus, urticaria, dehydration; gout;
tartrazine (in erythematous pregnancy, lactation
Increased risk of
Suppression or methenamine eruptions, rash
lactic acidosis with
elimination of Hippurate Physical: Skin
carbonic
bacteriuria marketed as GI: Nausea, color, lesions;
anhydrase
associated with Hiprex), aspirin abdominal cramps, hydration; ear
inhibitors (e.g.
pyelo-nephritis, (associated vomiting, lobes—tophi; joints;
acetazolamide,
cystitis, chronic with tartrazine diarrhea, anorexia, liver evaluation;
dichlorphenamide),
UTIs, residual allergy), stomatitis urinalysis, LFTs;
Methyler- NSAIDs, and
Methenamine Methergine urine lactation. GU: Bladder irritation, serum uric acid
gonovine antihypertensive
(accompanying Use cautiously dysuria, proteinuria,
agents (e.g. ACE
some neuro- with hepatic or hematuria, frequency, TEACHING
inhibitors).
logic disorders), renal urgency, crystalluria POINTS:
and in anatomic impairment, gout Take drug with
Increased plasma
abnormalities (causes urate Other: Headache, food. Complete the
concentration and
of the urinary crystals dyspnea, generalized full course
reduced clearance
tract to precipitate in edema, elevated of therapy to
with OCT2
urine), serum transaminase resolve the
inhibitors (e.g.
pregnancy, (with hippurate infection.
cimetidine,
severe salt)
dolutegravir,
dehydration. Take this drug at
ranolazine,
regular intervals
trimethoprim,
around the-
vandetanib,
clock; develop a
isavuconazole).
schedule with the
Cartalla, Sofia Millen B. Drug Study – OB Ward
2018 – 00229
BSN 2 – 1
help of your health
care provider.

Avoid alkalinizing
foods: Citrus fruits,
milk products; or
alkalinizing
medications
(sodium
bicarbonate).

Review other
medications with
your health care
provider.
Drink plenty of
fluids.

You may
experience these
side effects:
Nausea, vomiting,
abdominal pain (eat
frequent small
meals); diarrhea;
painful urination,
frequency, blood in
urine (drink plenty
of fluids).

Report rash, painful

urination, severe GI
upset.
 Cartalla, Sofia Millen B. Drug Study – OB Ward
2018 – 00229
BSN 2 – 1

GENERIC BRAND SPECIAL DRUG TO DRUG NURSING

DRUG NAME INDICATION SIDE EFFECTS
NAME NAME PRECAUTIONS INTERACTION CONSIDERATIONS

CV: Cardiac
Contraindicated
arrhythmias, PVCs, ASSESSMENT
with significant
hypertension, History: Significant
cephalopelvic
subarachnoid cephalopelvic
disproportion,
hemorrhage disproportion,
unfavorable fetal
To produce unfavorable fetal
positions
uterine Fetal effects: Fetal positions or
or presentations,
contractions bradycardia, neonatal presentations,
obstetric
during the third jaundice, low Apgar severe toxemia,
emergencies
stage of labor scores uterine inertia,
that favor
and to control hypertonic uterine
surgical
postpartum Cough or cold GI: Nausea, vomiting patterns, previous
intervention,
bleeding or medicines that cesarean
prolonged
hemorrhage contain a GU: Postpartum section
use in severe
decongestant, hemorrhage, uterine
toxemia, uterine
Lactation such as rupture, Physical: Fetal
Oxytocin Oxytocin Pitocin inertia,
deficiency pseudoephedrine pelvic hematoma, heart rate
hypertonic
or phenylephrine. uterine hypertonicity, (continuous
uterine patterns,
Unlabeled spasm, tetanic monitoring is
induction or
uses: To Drugs that contain contraction, rupture recommended);
augmentation
evaluate fetal caffeine of the uterus with fetal positions;
of labor when
distress excessive dosage or fetal-pelvic
vaginal delivery
(oxytocin hypersensitivity proportions; uterine
is contrain-
challenge test), tone; timing and
dicated, previous
treatment of Hypersensitivity: rate of contractions;
cesarean
breast Anaphylactic reaction breast examination;
section,
engorgement orientation, reflexes;
pregnancy.
Other: Maternal and edema; adventitious
fetal deaths when sounds; CBC,
Use cautiously
used bleeding studies,
with renal
to induce labor or in urinary output
impairment.
first or second stages
 Cartalla, Sofia Millen B. Drug Study – OB Ward
2018 – 00229
BSN 2 – 1
of labor; TEACHING
afibrinogenemia; POINTS:
severe The patient should
water intoxication know that the
with seizures and medication is
coma, maternal administered as a
death (associated part of an
with slow oxytocin immediate medical
infusion over 24 hr; situation.
oxytocin has
antidiuretic effects)

GENERIC BRAND SPECIAL DRUG TO DRUG NURSING

DRUG NAME INDICATION SIDE EFFECTS
NAME NAME PRECAUTIONS INTERACTION CONSIDERATIONS

ASSESSMENT:
Decreased anti-
History: Allergy to
Contraindicated infective response
any ingredient,
with allergy to to ciprofloxacin,
sulfite;
any ingredient; norfloxacin,
hemochromatosis,
sulfite allergy; ofloxacin;
CNS: CNS toxicity, hemosiderosis,
hemochromatosi separate doses by
Prevention and acidosis, coma and hemolytic anemias;
s, hemosi- at least 2 hr
treatment of iron death with overdose normal iron
derosis,
deficiency balance; peptic
hemolytic
Ferrous Ferrous Ferusulfate anemias GI: GI upset, ulcer, regional
anemias. Decreased
Sulfate Sulfate Iron anorexia, nausea, enteritis, ulcerative
absorption with
Dietary vomiting, colitis
Use cautiously antacids,
supplement for constipation, Physical: Skin
with normal iron cimetidine
iron diarrhea, dark stools lesions, color;
balance;
gums, teeth (color);
peptic ulcer, Decreased
bowel sounds;
regional effects of levodopa
CBC, Hgb, Hct,
enteritis, if taken with iron
serum ferritin and
ulcerative colitis.
iron levels
Cartalla, Sofia Millen B. Drug Study – OB Ward
2018 – 00229
BSN 2 – 1
Increased TEACHING
serum iron levels POINTS:
with chloram- Take drug on an
phenicol empty stomach with
water. Take after
Decreased meals if GI upset is
absorption of severe (avoid
levothyroxine; milk, eggs, coffee,
separate doses by and tea).
at least 2 hr
Use cautiously with
bladder outlet
obstruction,
decreased GI
motility, controlled
narrow-
angle glaucoma,
reduced hepatic
function,
myasthenia gravis,
impaired renal
function, pregnancy,
lactation.