PharmacyPrep.

Com Medical Microbiology and Infectious Diseases

PHARMACY PREP.
MICROBIOLOGY
1-What are the agents commonly found in sinusitis?
I-S. Pneumoniae
II-H. Influenza
III-Pseudomonas Aeroginosa
a) I only
b) III only
c) I and II only
d) II and III only
e) All are correct

2- E. Coli is the most common agent in UTI it can be classified as:

a) Bacillo
b) Cocci
c) Spiroquete
d) Vibrio
e) Coccobacilli

3- Which of the following antibacterial will not be effective against gram-

negative bacteria?
a) Ofloxacine
b) Penicillin V
c) Ciprofloxacine
d) Tetracycline
e) Clarithromycin

4- Which is/are correct about staphylococcus?

I- Most of the penicillins do not work properly in treating staphylococcus
II- Staphylococcus alter the effect of ampicillins
III-Methicillin Resistant Staphylococcus aureus is treated by vancomycin
a) I only
b) III only
c) I and II only
d) II and III only
e) All are correct

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5- Which of the following condition is/are characteristics of schistosomiasis?

I- Cirrhoses of liver
II- Jaundice
III- Bleeding
a) I only
b) III only
c) I and II only
d) II and III only
e) All are correct
6- Granulomatus is due to:
a) Mycobacterium infection
b) Plasmodium infection
c) Staphylococcus infection
d) Streptococcus infection
e) Salmonella infection

7- Which of the following is the agent causative of chancre?

a) Plamodium vivax
b) Treponema paladium
c) Staphylococcus aureus
d) Streptococcus viridians
d) Mycobacterium

8- All of the following are bacterial infection, EXCEPT:

a) Antibiotic associated colitis
b) Impetigo
c) Lyme disease
d) Rubella
e) Cellulites

9- Which of the following is the agent causative of diphtheria?

a) Plasmodium
b) Vibrio
c) Corynebacterium
d) Shigela
e) Neisseria

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10- Yersenia is the agent causative of which of the following diseases?

a) Schistosomiasis
b) Chancre
c) Diphtheria
d) Plague
e) Necrosting fasciitis

11- Which of the following organism contain taechoic acid on its cell wall?
a) Salmonela
b) Steptococcus
c) Haemophilus
d) Neisseria
e) Chlamydia

12- Which of the following organisms is NOT sexually transmitted

a) Neisseria gonorrhea
b) Treponema palladium
c) Molluscum contagious
d) Staphylococcus aureus
e) Clamydia trachomatus

13- Which of the following organisms can be transferred from mother to her
babies during labor?
a) Neisseria gonorrhea
b) Treponema palladium
c) Molluscum contagious
d) Chlamydia trachomatus
e) All of the above

14- Which of the following organism may cause gas gangrene?

a) Clostridium perfringenes
b) Borelia burgdorferi
c) Bacteroids
d) Clostridium tetani
e) Fusobacterium

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15- Staphylococcus aureus is the major agent causative of which of the

following disease?
a) Travel’s diarrhea
b) Encephalites
c) Nosocomial infections
d) Conjunctivitis in new borne babies
e) Sinusitis

16- Diseases that are not viral infections include:

I- Rabies
II- Lyme’s disease
III-Legionnaire’s disease
a) I only
b) III only
c) I and II only
d) II and III only
e) All are correct

17- Which of the following is the most common causative agent of

community-acquired pneumonia?
a) H. influenza
b) S. viridians
c) M. cataharlis
d) S. pneumoniae
e) Legionella

18- Common etiologic agents of community-acquired pneumonia include:

I- Escherichia coli
II- Haemophilus influenza
III- Mycoplasma pneumoniae
a) I only
b) III only
c) I and II only
d) II and III only
e) All are correct

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19- Eukariotic and prokaryotic cells may differ from each other due to:
a) Presence or nor of nucleon
b) Presence or nor of mitochondria
c) Structure of cell wall
d) Presence or nor of nucleic acid
e) Presence or nor of endoplasmic reticulum

20- Which of the following is/are the causative agent of ophthalmic neonate
infection in Canada?
I- Chlamydia trachomatus
II-Streptococcus aureus
III- Streptococcus pneumoniae
a) I only
b) III only
c) I and II only
d) II and III only
e) All are correct

21- Primary transmission of herpes is:

a) Cough
b) Lesions
c) Saliva
d) Blood
e) Air-conversation

22- Which of the following can be caused by streptococcus viridians?

a) Pyorrhea alveolar
b) Endocarditis
c) Septic sore throat
d) Scarlet and rheumatoid fever
e) Puerperal sepsis

23- Tinca pedis, the agent causative of Athletics’ foot, is classified as:
a) Gram-negative bacteria
b) Gram-positive bacteria
c) Protozoa
d) Fungi

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e) Plasmodium

24- Mode of Rabies’ transmition include:

a) Saliva of an infected animal
b) Direct contact
c) Inhalation of nasal secretion
d) Insect bit
e) Sexual transmition

25- What kind of bacterias is normally found colon?

a) 90% aerobics and 10% anaerobic
b) 90% anaerobic and 10% aerobics
c) 50% anaerobic and 50% aerobics
d) Anaerobic only
e) Aerobics only

26- Which of the following agents can be used to treat chickenpox?

I- Calamine lotion
II- Miceller colloidal bath
III- Diphenhydramine
a) I only
b) III only
c) I and II only
d) II and III only
e) All are correct

27- Which of the following organism cause anaerobic infections?

a) Chlostridium
b) Plasmodium
c) Mycoplasma
d) Corynobacterium
e) Chlamydia
28- All the following agents are gram-negative bacterias EXCEPT
a) H. influenza
b) N. gonorrhea
c) Salmonela
d) Fusobacterium
e) Corynobacteria

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29- All the following are examples of gram-positive bacterias, EXCEPT:

a) Streptococcus
b) V. colerae
c) Chlostridium
d) Staphylococcus
e) Corynobacteria

30- FALSE statement regarding bacterias include:

a) Grows extra or intracellulaly
b) Gram stain is the technique used to identify the bacterias
c) Bacterias grows only in the presence of oxygen
d) Bacterias can be classified in gram-negative and gram-positive
e) Bacterias are mainly formed of cell wall, cytoplasm and nucleo

31- All the differences regarding gram-positive and gram-negative are right,
EXCEPT:
a) Gram-positive has taechoic acid and peptydoglycan on its cell wall
b) Gram-positive has a single bilayer of phospholipids
c) Gram-negative has lipoproteins and peptydoglycan on its cell wall
d) Gram-negative has a two single bilayer of phospholipid
e) Gram positive bacterias has a stronger cell wall structure than gram-
negative bacterias

32- All are correct statements regarding virus, EXCEPT:

a) They can cause acute and chronic diseases
b) They cause only acute diseases
c) They have lifelong latency and long-term reactivation
d) They contain DNA or RNA in its structure
e) They are obligate intracellular organisms

33- Example of virus with lifelong latency and long-term reactivation may
include:
a) Herpes virus
b) Cold virus
c) Influenza virus
d) HIV virus

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e) Enterovirus

34- Chlamydia may cause all of the following conditions, EXCEPT:

a) Genitourinary infections
b) Respiratory infections
c) Conjunctivites
d) Endocarditis
e) Neonate ophthalmic infection

35- Mycoplasma is similar to bacteria. It differs from bacteria due to its lack
of:
a) Cytoplasm
b) Nucleo
c) ATP synthesis
d) Cell wall
e) Ability to grow in the presence of oxygen

36- Which of the following substances is mainly present in the cell wall of a
fungi microorganism?
a) Lipoproteins
b) Taechoic acid
c) Ergosterol
d) Peptydoglycan
e) Proteins

37- All of the following is/are true statements regarding HELMINTHS,

EXCEPT:
I- Multicellular organisms with complex life cycles
II- Can infect the intestine and other tissues
III- Schistossome, ascaris hookworms and strongloids are examples of
helminthes
a) I only
b) III only
c) I and II only
d) II and III only
e) All are correct

38- Which of the following organisms is/are the most often causative agents
of bacterial skin infections?

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I- Streptococcus pyogens
II- Staphylococcus aureus
III- Escherichia coli
a) I only
b) III only
c) I and II only
d) II and III only
e) All are correct

39- Papilloma virus causes a popularly infection called:

a) Common wart
b) Anatomical wart
c) Seborrheic wart
d) Venereal wart
e) Plane wart

40- All of the following are bacterial diseases of the skin or soft tissue,
EXCEPT:
a) Follculites
b) Erysipela
c) Fournier gangrene
d) Varicella
e) Cellulites

41- Which of the following is the most common agent causative of

encephalitis?
a) CMV
b) HSV-1
c) Mumps
d) Rabies
e) Echovirus

42- Which of the following organisms may cause meningitis?

I- Virus
II- Bacteria

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III- Fungi
a) I only
b) III only
c) I and II only
d) II and III only
e) All are correct

43- Joints and bones infections caused by bacteria include all of the
following, EXCEPT:
a) Lyme disease
b) Osteomyelitis
c) Arthritis
d) Osteoporosis
e) All are right

44- Correct statements regarding OSTEOMYELITIS include:

I- May be caused by S. aureus, S. epidermis and P. aeruginosa
II- Bacterial infection of bones and bone marrow
III- May be treated by vancomycin
a) I only
b) III only
c) I and II only
d) II and III only
e) All are correct

45- The most common agent causative of COLDS include:

a) Rhinovirus
b) Enterovirus
c) Adenovirus
d) Myxovirus
e) H. Influenza

46- Which of the following is/are agents causative of OTITE MEDIA?

I- S. pneumoniae
II- H. influenza

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III- M.cataharlis
a) I only
b) III only
c) I and II only
d) II and III only
e) All are correct

47- Common agent causative of otite extern commonly called swimmer’s

infection include:
a) Streptococcus
b) Mycoplasma
c) Pseudomonas
d) Legionella
e) Neisseria

48- Bacterias or virus may cause all the following eye infection, EXCEPT:
a) Blepharitis
b) Hardoleum
c) Conjuctivitis
d) Retinitis
e) Glaucoma

49- Common causative agent of peptic ulcer and gastric complications in the
stomach:
a) Salmonela
b) Shigella
c) S. aureus
d) H. pylori
e) E. coli

50- Mostly of the viral diarrhea infections is caused by:

a) Rhinovirus
b) Rotavirus
c) Adenovirus
d) Myxovirus

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e) Enterovirus

51- Infection of the large intestine called “Food Poisoning” can be caused
by:
a) S. aureus
b) Salmonela
c) Shigella
d) E. coli
e) All are correct

52- Correct statements regarding PERITONITES may include:

I- Infection caused by E.coli and Bactereoids
II- Inflammation of the peritoneal cavity
III- Treated with penicillin
a) I only
b) III only
c) I and II only
d) II and III only
e) All are correct

53- Antibiotic use associated colitis is an acute inflammation of the colon

caused by:
a) Clostridium difficile
b) Clostridium perfringes
c) Clostridium tetani
d) Clostridium botulinum
e) Clostridium agni

54- Correct statements regarding Travel’s diarrhea include:

I- Gastroenteritis in travelers
II- Normally caused by bacteria endemic to local water
III- Most common causative agents include E. coli and shigella
a) I only
b) III only

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c) I and II only
d) II and III only
e) All are correct

55- All of the following agents can cause malaria, EXCEPT:

a) P. falciparum
b) P. vivax
c) P. ovale
d) P. aeruginosa
e) P. malariae

56- Normal skin flora is constituted of:

I- Streptococcus epidermus
II- Streptococcus difteroids
III- Proprionobacterium
a) I only
b) III only
c) I and II only
d) II and III only
e) All are correct

57- The only of the following microorganism that cannot be treated by

penicillins or cephalosporins is:
a) Streptococcus
b) Staphylococcus
c) Mycoplasma
d) Clostridium
e) Chlamydia

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CORRECT ANSWERS
MICROBIOLOGY

1- C
Comments: S. Pneumoniae, H. Influenza and M. Catarlis are the most
common agent causative of sinusitis.

2- A
Comments: E. Coli is a bacillus gram-negative bacterium, the most common
causative agent of UTI.

3- B
Comments: Penicillin V is narrow spectrum penicillin effective only against
gram-positive bacterias.

4- E
Comments: Staphylococcus are gram-negative bacterias normally penicillin
resistant agents and may cause a condition called methicillin resistant
staphylococcus aureus.

5- E
Comments: Schistosomiasis is a blood fluke disease caused by schistosoma
and characterized by cirrhoses of liver, jaundice and bleeding.

6- A
Comments: Granulomatus is any small nodular delimitated aggregation of
mononuclear inflammatory cells representing a chronic inflammatory
response that may be initiated my mycobacterium.

7- B
Comments: Treponema palladium is the most common causative agent of
chancre.

8- D
Comments: Rubella is a viral infection caused by a togavirus.

9- C
Comments: Corynebacterium is the causative agent of diphtheria.

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10- D
Comments: Yersenia is a tribe of gram-negative, facultatevely anaerobic,
rod-shaped bacteria of the family Enterobacteriaceae, consisting of the
single genus Yersenia that causes plague.

11- B
Comments: Streptococcus is gram-negative bacteria therefore contain
taechoic acid on its cell wall.
12- D
Comments: Staphylococcus aureus is a gram-positive of bacteria not
sexually transmitted.

13- E
Comments: All Neisseria gonorrhea, Treponema palladium, Molluscum
contagious and Chlamydia trachomatus are organisms that may be
transferred from mother to her babies during labor.

14- A
Comments: Clostridium perfringenes is a gram-negative anaerobic organism
that may cause gas gangrene

15- C
Comments: Nosocomial infection is pertaining to or originating in the
hospital; said of infections not present or incubating prior to admittance to
the hospital normally caused by Staphylococcus aureus.

16- D
Comments: legionella gram-negative bacteria cause Legionnaire’s disease.

17- D
Comments: S. pneumoniae is one of the most common causative agents of
community-acquires pneumonia.

18- D
Comments: Escherichia coli may also cause community-acquired
pneumonia however it is not one of the most common agents.

19- A
Comments: Eukariotic organism has a defined nucleon while prokaryotic
organism lack nucleon.

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20- A
Comments: Chlamydia trachomatus is the most common causative agent of
ophthalmic neonate infection in Canada, normally treated by erythromycin.

21- B
Comments: Herpes is a viral infection caused by herpes virus and
transmitted from one to other only by direct contact with lesions.

22- B
Comments: Streptococcus viridian is the major causative agent of
endocarditis, an exudative and proliferative inflammatory alteration of the
endocardium.

23- D
Comments: 23- Tinca pedis is a fungal agent that may cause Athletics’ foot.
24- A
Comments: Rabies is an acute infectious disease of the central nervous
system caused by a rhabdovirus, and usually spread by contamination with
virus-laden saliva of bites inflicted by rabid animals.

25- B
Comments: 90% of the bacterias found in colon are anaerobic and 10%
normally are aerobics.

26- E
Comments: Effective treatments of chickenpox include calamine lotion,
miceller colloidal bath and diphenhydramine.

27- A
Comments: Clostridium is a gram-positive anaerobic agent therefore may
cause anaerobic infections.

28- E
Comments: Corynobacteria is a gram-positive bacteria normally causing a
disease called diphtheria.

29- B
Comments: V. colerae is an example of gram-negative bacteria.

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30- C
Comments: Bacteria may be classified as aerobic, growing in the presence of
oxygen or anaerobic when grows without the presence of oxygen therefore
the statement saying “Bacterias grows only in the presence of oxygen” is
false.

31- E
Comments: Gram-negative bacterias are constituted of double bilayer
phospholipid cell wall and gram-positive of one bilayer phospholipid cell
wall therefore gram-negative agents have a stronger cell wall.

32- B
Comments: Virus may cause acute illness (cold and influenza), lifelong
latency illness and long-term reactivation illness (herpes), and chronic
illness (AIDS) as well.

33- A
Comments: Herpes virus may cause an illness called herpes characterized by
lifelong latency and long-term reactivation.

34- D
Comments: Endocarditis is mainly caused by streptococcus viridians.

35- D
Comments: Mycoplasma is similar to bacteria organisms that differ mainly
due to lack of cell wall.

36- C
Comments: Ergosterol is the main substance present in the cell wall of a
fungi organism.

37- E
Comments: Helmints are multicellular organisms with complex life cycles
normally infecting the intestine and other tissues. Examples of helmints
include schistossome, ascaris hookworms and strongholds.

38- C
Comments: Streptococcus pyogens and Staphylococcus aureus are the most
often causative agents of bacterial skin infections that may include impetigo,

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follculitis, cellulites and erysipelas. Escherichia coli may cause a skin

infection called Fournier gangrene however it is not commonly involved in
skin infections.

39- A
Comments: Common wart is a kind of skin infection caused by papilloma
virus.

40- D
Comments: Varicella also known as chickenpox is a skin viral infection
highly contagious due to herpes virus and characterized a typical pruritic
vesicular lesions that are easily broken and become scabbed.

41- B
Comments: HSV-1 is the most common agent causative of encephalitis.
Other causative agents may include HSV-2, CMV, rabies, mumps, measles
and echovirus.

42- C
Comments: Meningitis can be classified as viral and bacterial depending the
agent causative that may include M. and S. pneumoniae, H. influenza,
listeria among others agents in bacterial meningitis, and HSV-1 and 2 in
viral meningitis.

43- D
Comments: Osteoporosis is neither bacterial nor viral infection. It is a
disease characterized by loss of bone mass not associated with causative
organisms.

44- E
Comments: Osteomyelitis is normally a secondary bacterial infection of
bones and bone marrow. The first infection is normally caused by wound,
surgery, an open fracture or a presence of a foreign body in the body as
platinum infected by S. aureus, S. epidermis and P. aeruginosa. Most of the
cases are treated with vancomycin.

45- A
Comments: Rhinovirus is the most common agent causative of viral colds.

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46- E
Comments: S. pneumoniae, H. influenza and M.cataharlis are all causative
agents of otite media.

47- C
Comments: Pseudomonas is a common agent causative of otite extern
normally called swimmer’s ear infection

48- E
Comments: Glaucoma is caused by intraocular pressure.

49- D
Comments: H. pylori is a gram-negative bacteria common causative agent of
peptic ulcer and gastric complications in the stomach.

50- B
Comments: Rotavirus Norwalk virus is the main virus implicated in viral
diarrhea.

51- E
Comments: “Food Poisoning” is a common infection of the large intestine
caused by many different organisms that may include S. aureus, Salmonella,
Shigella and E. coli as the most common agents. They cause the infection by
producing enterotoxin or invading the gut mucosa or both.

52- C
Comments: Peritonitis is an inflammation of the peritoneum; a condition
marked by exudation in the peritoneum of serum, fibrin, cells and pus. It is
attended by abdominal pain and tenderness, constipation, vomiting and
moderate fever mainly caused by E. coli and Bactereoids.

53- A
Comments: Clostridium difficile is the most common causative agent of
pseudomenbranous colitis, a colitis inflammation associated with the used of
antibiotics.

54- E

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Comments: Travel’s diarrhea is a gastroenteritis condition in travelers

normally caused by bacteria endemic to local water. E. coli and shigella are
the main causative organisms.

55- D
Comments: P. aeruginosa is not a causative agent of malaria.

56- E
Comments: Organisms naturally present in the normal skin flora include
Streptococcus epidermis, Streptococcus difteroids and Proprionobacterium.

57- C
Comments: Mycoplasma differs from bacteria by the lack of cell wall.
Penicillins are antibiotics inhibitor of cell wall synthesis, therefore cannot be
used against mycoplasma because these organisms lack cell wall.

BIBLIOGRAPHIC REFERENCE

1- COMPREHENSIVE PHARMACY REVIEW – Lippincott William &

Wilkins – Fourth edition

2- CPS-COMPENDIUM OF PHARMACEUTICALS AND SPECIALITIES

- Canadian Pharmacist Association – 2001 edition.

3- MEDICAL DICTIONARY – Dorland’s illustrated – 27th edition.

4- PHARMACY PREP – Lectures series & study guide for Evaluating

Examination-TIPS - 2003/2004

5- THERAPUTIC CHOICES – Canadian Pharmacist Association -Third

edition

6- USP DI – Drug Information for the Health Care Professional–15th edition

– Volume I.

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