Pathophysiology of Chorioamnionitis: Predisposing Factors
Pathophysiology of Chorioamnionitis: Predisposing Factors
Pathophysiology of Chorioamnionitis: Predisposing Factors
infected babies
develop
pneumonia (lung
Predisposing Factors: infection) or
young age (e.g., less than 21 years old); bacteremia
low socioeconomic status; (however, this is
first pregnancy; more common in
long labor; preterm infants);
prolonged rupture of the membranes (bag of waters); less than 1% of
term infants and a
rupture of membranes at an early gestational age;
slightly higher
multiple vaginal examinations during labor (only in women with
percentage of
ruptured membranes);
preterm infants
pre-existing infections of the lower genital tract (bacterial vaginosis develop meningitis
and group B streptococcal infection); and (infection of the
internal fetal and uterine monitoring. lining of the brain
and spinal cord);
and
although death in
term babies is very
unusual, up to
15% of infected
Chorioamnionitis usually develops when bacteria that are part of the normal vaginal flora "ascend" into the preterm infants die
uterine cavity. The amniotic fluid and placenta, as well as the baby, become infected. E. coli, group B because of the
infection or other
streptococci, and anaerobic bacteria are the most common causes of chorioamnionitis, though, E. coli and
complications
group B streptococci are also the two most common causes of infection in newborns. such as
respiratory
distress syndrome
and bleeding into
Chorioamnionitis can lead to serious complications in both the brain.
mother and baby and is usually considered a medical
emergency