Methergine is used to manage and prevent postpartum and postabortal hemorrhage by producing firm uterine contractions and decreasing bleeding. It should not be used in pregnancy, toxemia, hypertension, ergot hypersensitivity, or before delivery of the placenta due to risks of vasospasm. Nurses should monitor for signs of vasospasm when administering Methergine and ensure no drug interactions with antifungals, clarithromycin, erythromycin, or protease inhibitors which can increase this risk. They should also assess uterine tone and bleeding levels and monitor for signs of improved bleeding control or side effects like severe cramping.
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Methergine is used to manage and prevent postpartum and postabortal hemorrhage by producing firm uterine contractions and decreasing bleeding. It should not be used in pregnancy, toxemia, hypertension, ergot hypersensitivity, or before delivery of the placenta due to risks of vasospasm. Nurses should monitor for signs of vasospasm when administering Methergine and ensure no drug interactions with antifungals, clarithromycin, erythromycin, or protease inhibitors which can increase this risk. They should also assess uterine tone and bleeding levels and monitor for signs of improved bleeding control or side effects like severe cramping.
Methergine is used to manage and prevent postpartum and postabortal hemorrhage by producing firm uterine contractions and decreasing bleeding. It should not be used in pregnancy, toxemia, hypertension, ergot hypersensitivity, or before delivery of the placenta due to risks of vasospasm. Nurses should monitor for signs of vasospasm when administering Methergine and ensure no drug interactions with antifungals, clarithromycin, erythromycin, or protease inhibitors which can increase this risk. They should also assess uterine tone and bleeding levels and monitor for signs of improved bleeding control or side effects like severe cramping.
Copyright:
Attribution Non-Commercial (BY-NC)
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Download as DOCX, PDF, TXT or read online from Scribd
Methergine is used to manage and prevent postpartum and postabortal hemorrhage by producing firm uterine contractions and decreasing bleeding. It should not be used in pregnancy, toxemia, hypertension, ergot hypersensitivity, or before delivery of the placenta due to risks of vasospasm. Nurses should monitor for signs of vasospasm when administering Methergine and ensure no drug interactions with antifungals, clarithromycin, erythromycin, or protease inhibitors which can increase this risk. They should also assess uterine tone and bleeding levels and monitor for signs of improved bleeding control or side effects like severe cramping.
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Name of Drug Classification & Indication Contraindication & Adverse Drug to Drug Interaction Nursing Responsibilities
Reaction
Methergine Classification: Contraindication: Antifungals like: 1. Before administering the
(Methylergonovine Maleate) PC: Ergot Alkaloid and Pregnancy Azole methergine, give only if Derivative Toxemia (litraconazole, the solution is clear and Dosage: TC: oxytoxic, lactation Hypertension ketoconazole, colorless; discard if 0.6 mg/3 ml stimulant Ergot hypersensitivity vericonazole) – ampule is discolored. To include labor and Increase risk of 2. Note reason for therapy. Preparation: Indication: spontaneous vasospasm leading to List drug prescribe to Intramascular Management and abortions. cerebral ischemia or ensure none interact. prevention of postpartum Administration before ischemia of 3. Assess fundal tone and and postabortal hemorrhage delivery of placenta. extremities; do not nonphasic contractures, by producing firm uterine Use with CYP3A4 use together. massage to check for contractions and decreasing inhibitors. Clarithomycin – relaxation or severe uterine bleeding. Increase risk of cramping. Indication: vasospasm leading to 4. Monitor Vital Signs, CBC, Headache cerebral ischemia or and calcium; Correct if Dizziness ischemia of low to improve drug Sweating extremities; do not effectiveness and assess Nasal Congestion use together. for decrease milk Leg cramps Erythomycins – production. Increase risk of 5. Report frequency, vasospasm leading to amount, color, any cerebral ischemia and associated S&S. Ensure ischemia of placenta completely extremities; do not passed or removed. use together. 6. Take only directed and Protease inhibitors do not exceed dosage – increase risk of 7. Report any severe vasospasm leading to cramping, headaches, or cerebral ischemia or increase bleeding. ischemia of 8. Evaluate for improved extremities; do not uterine tone and control use together. of postpartum hemorrhage.