Hosk Er 2019
Hosk Er 2019
Hosk Er 2019
a n d We l l n e s s in Yo u t h
T h ro u g h P h y s i c a l A c t i v i t y,
N u t r i t i o n , a n d Sl e e p
Daniel K. Hosker, MDa,*, R. Meredith Elkins, PhD
b,c,1
,
Mona P. Potter, MDc,d,1
KEYWORDS
Mental health Wellness Exercise Sports Nutrition Diet Sleep
Child and adolescent
KEY POINTS
From 3 to 5 days of moderate to vigorous aerobic exercise for 45 to 60 minutes confers
benefits to youth physical and mental wellness. Additional benefits are seen with sports
participation.
Nutritional patterns that are high in a variety of fruits and vegetables, whole grains, sea-
food, and nuts, moderate in low-fat dairy products, low in red meat, and very limited in
processed foods, saturated and trans fats, added sugars, and sodium have been associ-
ated with improved mental health outcomes across the lifespan.
Following age-appropriate recommendations for sleep duration is associated with im-
provements in mental health and well-being. Engaging in consistent and calming bedtime
routines, creating a restful and comforting sleep environment, and ensuring that children’s
physical and emotional needs are met during the daytime can increase the likelihood of
obtaining adequate sleep duration.
Seligman’s PERMA (positive emotions, engagement, relationships, meaning, and accom-
plishment) model is a useful construct to approach improving physical activity, eating, and
sleep to yield improved physical and mental wellness in youth.
Disclosures: None.
a
Psychiatry, Massachusetts General Hospital, 32 Fruit St, Boston, MA 02114, USA; b McLean
Anxiety Mastery Program, McLean Hospital, 799 Concord Avenue, Cambridge, MA 02138, USA;
c
Department of Psychiatry, Harvard Medical School, 25 Shattuck St, Cambridge, MA 02115,
USA; d McLean Child and Adolescent Psychiatry Outpatient Services, McLean Hospital, 115 Mill
St, Belmont, MA 02478, USA
1
Present address: 799 Concord Avenue, Cambridge MA 02138.
* Corresponding author. 4 Emerson Place Apartment 1113, Boston, MA 02114.
E-mail address: [email protected]
INTRODUCTION
Approximately 1 in every 4 to 5 youth in the United States meet criteria for a mental
disorder with severe impairment before they reach adulthood.1 Improving health
care and implementing practices to decrease vulnerability to psychiatric symptoms
is a vital part of treatment of this population. Conventional first-line treatments such
as cognitive behavior therapy (CBT) and psychopharmacology may be moderately
effective, but too often fail to improve some symptoms, with medications carrying a
risk for serious side effects.2,3 Alternative or augmenting treatment interventions
such as incorporating physical activity, improving nutrition, and optimizing sleep allow
clinicians to fashion a more comprehensive approach to mental health treatment of
youth.
The landscape of youth mental health and wellness is evolving as providers increas-
ingly view interventions through a more holistic lens. Although many research studies
have shown the benefits of physical activity, nutrition, and sleep in youth, few studies
show how these factors interact with emotional health and wellness. The existing
research in this area is largely cross-sectional, which precludes a demonstration of
causality, and is also limited by researchers’ use of heterogeneous protocols and
measurements, small sample sizes, and nonclinical participants. These methodolog-
ical limitations highlight the complexity involved with researching such dynamic vari-
ables and interactions. Given the lack of a robust evidence base, it is difficult to
standardize recommendations, particularly in relation to physical activity and nutrition.
However, the existing research studies suggest that optimizing physical activity, nutri-
tion, and sleep confers numerous benefits for youth mental health and wellness, and
exerts a positive impact on the developmental trajectory of young people vulnerable
to, or struggling with, psychiatric disorders.
Table 1
Associations between physical activity and social-emotional and academic wellness and
possible clinical implications
Domain of
Benefits Trait Clinical Implications
Social-Emotional Enhanced self-concepta,5 Improved self-perception and value of
Increased life skillsa,5 own qualities and abilities
Improved self-esteema,5 More likely to express confidence in self
Protective for shy Increased engagement in novel
childrena,b,5 activities and/or new situations
By learning to tolerate distress, can
challenge self further, and reap
benefits when overcoming new tasks
Academic Improved classroom Improvements in grades and test
behavior, with decreased scores6
disruptive behaviors6 Reduce the likelihood of negative
Improved academic classroom behaviors6
achievement6 Greater confidence in school-based
Cognitive and metacognitive tasks
benefits including learning, Improved ability to attend to academic
memory, attention and daily tasks (eg, homework, quizzes,
management, and tests)6
processing speed4,7–9
a
Associations seen with sports participation.
b
As measured by decreased reports of anxiety symptoms.
benefits, and significantly fewer social benefits than team participation.5 Children who
are active in sports are more likely to be physically active in adulthood, which is crit-
ically important because more physically active adults lead physically and emotionally
healthier lives.5,23
How It Works
The mechanisms of action by which physical activity and sports confer benefits to
different domains of mental health and wellness are multifactorial, but they tend to
be in 2 broad categories: neurobiological and psychosocial. Although the neurobiolog-
ical cannot be separated from the psychosocial, and vice versa, conceptualizing it in
this way can be helpful, as summarized in Table 3.
Clinical Assessment
Before recommending physical activity or sports as part of a therapeutic intervention,
it is important to clarify what the child is already doing, the child’s activity preferences,
and potential obstacles to being physically active. The answers to these questions
may prompt further inquiry if, for example, the clinician suspects that the child is exer-
cising too much in the context of an eating disorder or too little because of ongoing
medical issues. Sample questions to help in the assessment of children’s physical ac-
tivity are listed in Table 4. It is important to ask these of the parent and child if possible,
because there can be discrepancies that are important to address. These questions
can be modified to be asked directly of the child as the clinical context allows.
Recommendations for Physical Activity
Clinicians should consider prescribing physical activity as a way of promoting both
physical and emotional health in youth, especially given the increasing evidence
4 Hosker et al
Table 2
Associations between physical activity and psychiatric disorders
Depression and Protective effect against depression across age, gender, and
suicidality geographic regions across the world10
Treatment effect sizes similar to that of antidepressant and CBT
therapy for depressive symptoms in children and adolescents2,11–13
Lower odds of sadness, suicidal ideation, or suicidal attempts in high
school studentsa,14
Reduction in suicidal ideation and attempts in bullied high school
studentsa,15
Decreased suicidal ideation and intention in adolescents involved
with team sportsb,g
Decreased hopelessness, depression, and suicidality among college
students16
Inverse bidirectional association between depressive symptoms and
physical activity (ie, increased physical activity precedes decreased
depressive symptoms, and increased depressive symptoms precede
decreased physical activity)17
ADHD Improvements in core ADHD symptoms (inattention, hyperactivity,
and impulsivity)c,3
Improved social, motor, behavioral, and emotional functioningd,18
Physical activity in adolescence may decrease ADHD symptoms in
early adulthood19
Anxiety May improve symptoms of anxiety in children and adolescents6
Decreased social anxiety with lowered social isolation5,g
Substance use Lower levels of alcohol, cigarette, and marijuana use among high
school studentse,20
Psychosis and Decreased physical activity and poorer cardiorespiratory fitness have
antipsychotic use been seen in adolescents who develop a psychotic illness21
Lower measures of adiposity and improved insulin resistance in
children treated with a second-generation antipsychoticf,22
regarding the negative health impact of sedentary behaviors, with US children spending
approximately 7.7 h/d (55% of their monitored waking time) being sedentary.4
As discussed earlier, it is difficult to draw conclusions regarding optimal types or
“doses” of physical activity for mental health benefits given the overall heteroge-
neous nature of the research and lack of methodologically rigorous studies. Howev-
er, common trends among the data across mental health and wellness domains
suggest that to obtain the mental health benefits, physical activity in youth should
involve:
At least 45 to 60 minutes of physical activity each day2,4,10,14,18
From 3 to 5 days a week of moderate to vigorous aerobic activity2,4,10,14,18
Promoting Mental Health and Wellness 5
Table 3
Means by which physical activity and sports may confer benefits to youth mental wellness
Conceptual
System Mechanism of Action
Neurobiological Modify inflammatory and oxidative stress responses10
Promote neurogenesis, synaptogenesis, myelination, and angiogenesis to
aid brain development through neurotrophic factors (such as BDNF)2,3,10,24
Modulate monoamines (serotonin, dopamine, norepinephrine),
endorphins, and endocannabinoids2,3,10,24
HPA axis regulation2
Psychosocial Behavioral activation with positive reinforcement2
Satisfy basic psychological needs for social connectedness and autonomy24
Mastery of a skillset2,24
Promote confidence through achievement2,24
Exposure to difficult situations and using distress tolerance
Increasing overall self-efficacy and self-concept2
Table 4
Example questions of parents when assessing physical activity in youth in the context of a
mental health evaluation
Example Questions
Type What types of activities or sports does your child participate in?
Are these activities mostly aerobic (eg, running, swimming, soccer) or
anaerobic (eg, push-ups/sit-ups, weight lifting, tug-of-war)?
Frequency How many days in a week does your child exercise or play sports?
What does your child do during “spare time”?
How consistently is the child exercising or staying physically active? (eg, spurts
every so often, only during a sports season)
Duration How many minutes does your child exercise on average each day/week?
Do you have any worries that your child exercises too much? If yes, why do you
think so?
Intensity When your child is exercising or playing sports, is the intensity most
comparable with walking, jogging, or running?
Does your child usually end up sweating?
Is your child breathing hard during some, most, or all of the activity?
Preferred What is your child’s favorite way to be physically active?
exercise Does your child prefer to play sports alone or on a team?
What have you seen your child enjoy most while engaged in physical activity?
Obstacles to Is there anything keeping your child from being more physically active?
physical Are there any medical concerns regarding your child being more physically
activity active?
Does your child have appropriate strength and motor coordination?
Any concerns for bullying when your child is playing/practicing physical
activities?
What other activities compete with time for physical activities? (eg, screen
time, hanging out)
Supporting How has physical activity altered your child’s nutrition?
questions How has physical activity affected your child’s sleep?
Do you believe that your child is able to appropriately recover from the
physical activity?
6 Hosker et al
NUTRITION SCIENCE
Clinical Relevance and Current Research
A global obesity epidemic (United States currently ranked #1 in childhood obesity
rates [12.7%]) has called attention to the need for intervention in multiple domains,
including diet and nutrition.25 Emerging evidence argues the case for nutritional
awareness not only for its effects on physical health, but also because of its relation-
ship with mental health and well-being. Much of the investigation historically has
focused on the role of individual nutrients on mental health. For example, magne-
sium,26 zinc,27 and omega-3 fatty acids28 have been studied in relation to anxiety
and depression.
However, recent focus has broadened the scope to considering dietary patterns.
Data that support an association between unhealthy patterns of eating and poor
mental health (eg, depression, anxiety), as well as healthy patterns of eating and
improved mental health, are emerging for all stages of life. Table 6 summarizes major
findings, including 1 adult randomized control trial, the Supporting the Modification of
lifestyle In Lowered Emotional States (SMILES) trial.41
How It Works
Multiple pathways have been proposed in the association between diet and mental
health, including (but not limited to) inflammation,42 oxidative stress,43 and changes in
brain structure.44 For example, unhealthy diet patterns have been associated with lower
left hippocampal volume in animal and human studies, as well as the reverse for adults
with healthy diet patterns, possibly mediated via brain-derived neurotropic factor.29,45
In addition, although in early stages, there has been growing interest in the gut
microbiome (the approximately 100 trillion microorganisms that exist in the gastroin-
testinal tract) and its relationship with mental health.46 The gut microbiome has
been noted to be a virtual organ, producing metabolites that influence the host in
many ways, with emerging evidence showing cross-influence with multiple systems,
including neurobehavioral, metabolic, immune, and endocrine systems.47 Although
most data regarding the microbiota gut-brain connection currently come from animal
models, human studies are emerging.46,48,49
7
Table 5
Clinical considerations when increasing and selecting physical activities for youth
Clinical
Consideration Clinical Example/Recommendations
Increasing Physical Start early Encourage play at home and in the neighborhood
Activity Provide time for structured and unstructured
physical activity in and out of school
Promote activities the child can enjoy for a
lifetime (eg, swimming, cycling)
Start low, go slow Risk of injury is directly related to the gap
between usual level of activity and a new level of
activity. Keep the gap small, allowing the body to
adapt
Use the child’s level of fitness to guide the level of
effort expected
First, increase the number of minutes (duration)
of an activity, then the number of days
(frequency), then increase from moderate to
vigorous intensity
Can add light-intensity to moderate-intensity
activities (eg, short walk) to weekly routine
Increase activity by small amounts every week or
two for youth (considering age, level of fitness,
and level of experience)
Keep activities enjoyable
Vary activities to avoid muscle overuse injuries
Medical clearance Although medical clearance should not be
necessary for most children, periodic monitoring
and collaboration with relevant providers may be
appropriate for children with known medical
conditions that may be adversely affected by
rigorous exercise3,4
Replace sedentary Replace TV watching after school with sports
behavior with participation
activity when Encourage walking or biking when possible
possible instead of driving
Limit and replace screen time with family
activities and outside games
Choosing a Preschool-aged Moderate intensity
Physical Activity children Tag, playing on playground, riding a tricycle or
by Age and bicycle; games requiring catching, throwing, or
Aerobic Intensitya kicking
Vigorous intensity
Running, skipping, dancing, jumping,
gymnastics, swimming
School-aged Moderate intensity
children Brisk walking, riding a bicycle, hiking,
swimming, games that require catching and
throwing
Vigorous intensity
Running, riding a bicycle, jumping rope, cross-
country skiing, sports (eg, soccer, basketball,
tennis)
Adolescents Moderate intensity
Brisk walking, riding a bicycle, recreational
activities (eg, kayaking, hiking, swimming)
Vigorous intensity
Running, riding a bicycle, martial arts, vigorous
dancing, sports (eg, soccer, basketball, tennis)
Table 5
(continued )
Clinical
Consideration Clinical Example/Recommendations
Special During the Female youth may need additional support and
Considerations transition to encouragement to maintain beneficial levels of
adolescence, physical activity
physical activity This may be provided by health professionals,
in girls decreases parents, coaches, teachers, peers, and so forth
significantly
compared with
boys (this
disparity persists
into adulthood)
Children and Youth with disabilities should partner with a
adolescents with health care or physical activity professional to
disabilities are understand appropriate types and amounts of
more likely to be physical activity for them to assist in decreasing
inactive than inactivity
those without
disabilities
a
Because the evidence for mental health and wellness benefits in youth are most supported from
aerobic activities, these are presented here.
Adapted from US Department of Health and Human Services. Physical activity guidelines for
Americans. 2nd edition. Washington, DC: US Department of Health and Human Services; 2018.
Clinical Assessment
Many factors contribute to food choice, including (but not limited to) biological need/
appetite, taste preference/sensory stimulation, family/peer/social/cultural influence,
habit/routine, cost/access/availability, mood/emotions/craving, health attitudes, and
weight awareness. Given the impact on physical and mental health, clinicians are
encouraged to evaluate for food insecurity (lack of consistent access to adequate
food). The who, what, when, why, and where of eating patterns can offer opportunities
to recognize processes that are going well and help bring attention to areas in need of
intervention. Given the potential impact of the family system on the eating patterns of
children, thorough assessment incorporates nutritional patterns of the family sys-
tem.52 Sample questions and associated recommendations for parents are listed in
Table 7 to assist in this assessment. These questions can be modified to be asked
directly of the child as the clinical context allows.
Promoting Mental Health and Wellness 9
Table 6
Association between dietary pattern and mental/emotional health across the life span
Table 6
(continued )
Stage of Life Mental Health Outcomes
Adulthood A systematic review and meta-analysis of 13 cross-sectional and
cohort studies concluded that healthy diet pattern was significantly
associated with reduced odds of depression, but no statistically
significant association was observed between unhealthy (Western)
diet and depression (trend toward positive association)39
A meta-analysis of 22 studies investigated the association between
a Mediterranean-style diet and brain diseases and determined that
higher adherence to the Mediterranean-style diet was associated
with reduced risk for depression and cognitive decline40
Randomized controlled trial
Jacka and colleagues,41 2017, Supporting the Modification of
lifestyle In Lowered Emotional States (SMILES) trial: included 67
adults diagnosed with depression; 31 in dietary support group and
25 in social support control group for 12 weeks
The dietary support group received 7 60-min individual
ModiMedDiet counseling sessions: diet rich in vegetables, fruit,
and whole grains, with an emphasis on increased consumption of
oily fish, extravirgin olive oil, legumes, and raw unsalted nuts,
and moderate consumption of red meat and dairy
The dietary support group showed significantly greater
improvement in depressive symptoms between baseline and
week 12 compared with the control group (32.3% vs 8%),
number NNT based on remission score was 4.1 (95% CI of NNT,
2.3–27.8)
All effects were independent of any changes in BMI, self-efficacy,
smoking rates, and/or physical activity
Abbreviations: BMI, body mass index; CI, confidence interval; NNT, needed to treat.
Table 7
(continued )
Category Sample Questions Recommendations
When do they How often are they eating Problem-solve limitations to eating
eat? breakfast? breakfast, because associations
How about snacks? exist between having breakfast
What is the daily eating schedule? and improved student psychosocial
and academic functioning58
Deliberately plan snack content
and timing to manage energy
needs of the child
Develop a list of acceptable healthy
snacks and keep them readily
available:
Create a kids’ snack drawer/
cabinet that offers easily
accessible healthy snacks; have
fruits and vegetables precut
and available for munching in
a bowl on the counter/kitchen
table
Where do they Are they eating at the kitchen/ Maximize eating in spaces that
eat? dining room table? promote mindful eating (eg, eat
How often are they eating in front snacks at the kitchen table instead
of TV/screens? of in front of TV/computer/phone)
How often are they eating at fast
food restaurants?
SLEEP SCIENCE
Clinical Relevance and Current Research
Along with diet and exercise, sleep is an essential activity that plays a crucial role in
emotional and physical development, health, and well-being. Quality sleep is asso-
ciated with positive health and emotional outcomes in youth, including, but not
limited to, improvements in attention, learning, academic performance, memory,
Promoting Mental Health and Wellness 13
How It Works
Sleep architecture throughout most of childhood, adolescence, and adulthood con-
sists of 2 stages: non–rapid eye movement sleep (NREM) and rapid eye movement
sleep (REM), which are characterized by distinct electroencephalographic patterns
and physiologic features. NREM sleep progresses through 3 stages of increasingly
deep sleep and is considered necessary for rest and restoration. REM sleep follows
stage 3 of NREM sleep, and is characterized by bouts of rapid eye movements, the
suppression of muscle tone, and increases in brain activity, during which dreaming
occurs. REM sleep is associated with dreaming, and is thought to play a role in
the consolidation of memory and is crucial for the healthy development of the central
nervous system. Children and adults enter sleep at stage 1 of NREM sleep and prog-
ress through NREM and REM cycles, which lengthen across development from 45 to
60 minutes in infancy to 90 to 110 minutes in childhood and adulthood, with brief pe-
riods of waking in between cycles. The amount of sleep necessary per 24-hour
period peaks in neonates and decreases across childhood and adolescence.71
Table 8 outlines consensus guidelines from the American Academy of Sleep Medi-
cine detailing the recommended amount of sleep in childhood and adolescence by
age group.
14 Hosker et al
Table 8
Recommended minimum and maximum hours of sleep recommended per age group within a
24-hour period
Adapted from Paruthi S, Brooks LJ, D’Ambrosio C, et al. Recommended amount of sleep for pedi-
atric populations: a consensus statement of the American Academy of Sleep Medicine. J Clin Sleep
Med 2016;12(6):785–6.
Clinical Assessment
Despite recommendations that sleep assessment be part of child well-visits, sleep is
not regularly addressed in pediatric primary care.72 It is therefore essential that mental
health providers recognize the links between sleep and emotional well-being, and
continuously assess and address sleep issues in the course of their work with youth.
This assessment includes recognizing that both too little and too much sleep are asso-
ciated with poorer outcomes.61 Tools to assess pediatric sleep include clinical inter-
views, sleep diaries, and sleep questionnaires, such as the parent-report Children’s
Sleep Habits Questionnaire73 or the adolescent-report School Sleep Habits Survey.74
Clinicians should also assess environmental factors related to sleep quality and can be
influential in assisting families to implement evidence-based behavioral recommenda-
tions to improve sleep. Table 9 highlights potential areas of inquiry for parents or
guardians to facilitate assessment of sleep hygiene and environmental factors. These
questions can be modified to be asked directly of children as clinical context allows.
Recommendations for Sleep
Guidelines from the American Academy of Pediatrics detailed earlier can inform age-
based recommendations for sleep duration, recognizing that the sleep needs of indi-
vidual children may vary depending on the unique genetic, behavioral, medical,
emotional, and environmental factors at play. In addition to recommendations about
the duration of sleep, there are several environmental factors that should be consid-
ered, outlined in Table 9. In short, parents of children and adolescents should estab-
lish regular bedtimes and wake times to facilitate age-based recommendations for
sleep duration. Implementing a consistent, predictable, and calming bedtime routine
is particularly beneficial for children aged 12 years and younger.60,75 Most research
supports recommendations that sleep should occur:
Independent of parental presence
In a cool (16 –19 C [60 –67 F]), dark, comfortable, quiet room reserved primarily
for sleeping60
With minimal exposure to electronics, particularly in the evenings, and all elec-
tronic devices should be removed from children’s rooms
In addition, sleep is optimized when children maintain a healthy diet, participate in
regular physical activity, and have their emotional needs met during the day.60
Some children require more targeted interventions to improve their sleep. Emerging
evidence suggests that cognitive behavioral and mindfulness-based treatments may
15
Table 9
Sample questions to assess sleep hygiene in the context of a mental health evaluation and
related recommendations
Table 9
(continued )
Example Questions Recommendations
Sleep Where does the child sleep in Whenever possible, sleep should occur
Environment the home? independently (ie, in the child’s own
Does the child sleep alone? room) and in a dark room
With siblings? With parents? Consider using white noise machines
What is the child’s sleep or fans to block sounds that may cause
environment like? (eg, bright, wakefulness
noisy, comfortable, free of Sleep is optimized when the bedroom
electronics) temperature is 16 –19 C [60 –67 F] (ie,
the room should feel mildly chilly
when you get out of bed)
Reduce exposure to blue light (ie, LED,
florescent lights, screens) before bed;
shift electronics to nighttime settings
in the evening if they must be used
before bed
Whenever possible, avoid exposure to
screens entirely for 1–2 h before
bedtime. Keep electronics away from
the bed or bedside to avoid
interruptions from notifications
Prevent viewing the clock by turning
the clock face away or removing it
entirely, because clockwatching can
increase anxiety about not getting
enough sleep
Sample Questions
PERMA Factor15 Physical Activity Nutrition Sleep
Positive emotion What types of physical activity make you Which meals make you feel content? What is something you do before you go
feel excited? Happy? Energized? Happy? Energized? Connected to others? to bed that helps you to feel calm?
What positive emotions do you feel when What are some of your favorite foods? What positive emotions do you feel when
you have finished working out? What positive emotions do you feel when you lie down in your bed to sleep at night?
How does exercising with other people, or you enjoy a nutritious meal? Is this any How you feel when you wake up after a
playing a team sport, make you feel? different from when you make less healthy good night’s sleep?
choices?
Engagement Which physical activities or sports best Do you prepare meals yourself or with Do you look forward to sleeping? When
capture your interest? others? What are some of the benefits of you lie down, do you enjoy how your
What do you like about participating in both? pillow and covers feel? Do you let go of
team sports? How about individual sports? Where do you like to eat? Do you enjoy your thoughts about the day to enjoy
Does competition help you push yourself, going to restaurants, or do you prefer being in your bed?
or impair your performance? eating meals at home? What is a relaxing activity that you do
What do you like to do while you are before bed? Do you like to read a book,
17
18
Hosker et al
Table 10
(continued )
Sample Questions
PERMA Factor15 Physical Activity Nutrition Sleep
Meaning What do you value about being physically Why does eating healthily matter to you? What is something that you have in your
active? Why is it important to you? Are there special meals that you and your sleep environment/bedroom that is
How do you feel about yourself when you family make during holidays or other significant to you? A favorite stuffed
are physically active on a regular basis? special occasions? animal? A picture of loved ones by your
What does winning or losing at a What foods have meaning to you? Do any bed?
competitive physical activity mean to you? foods remind you of happy times, Do you value your sleep? Does it make you
How does winning or losing affect you? holidays, or special people? feel better?
Do you value and think or talk about your
dreams?
Accomplishments Tell me about something that you Do you feel a sense of pride when you Do you notice any relationship between
accomplished that was physically make healthy food choices instead of your sleep and your school performance
challenging. How did you surprise unhealthy ones? (eg, paying attention in class)?
yourself? What is it like for you to prepare and eat a How does sleep affect how effective you
What is it like for you when you are part of well-balanced meal? are at getting things done the next day?
a team that wins or performs well?
How do you think your schoolwork is
affected by getting exercise? How about
your social life?
Promoting Mental Health and Wellness 19
SUMMARY
The benefits conferred by physical activity, balanced nutrition, and quality sleep to
youth physical well-being have generally been accepted. Emerging evidence con-
tinues to shed light on their benefits for youth mental health and wellness as well,
including psychiatric disorders. These benefits seem to occur through multifactorial
effects on neurobiological and psychosocial development. Integrating ongoing as-
sessments and interventions related to these lifestyle domains within clinical practice
promotes positive mental as well as physical health in youth, including enhancing
treatment of psychiatric disorders and their impacts on functioning.
REFERENCES
13. Whittington CJ, Kendall T, Fonagy P, et al. Selective serotonin reuptake inhibitors
in childhood depression: systematic review of published versus unpublished
data. Lancet 2004;363(9418):1341–5.
14. Sibold J, Edwards E, Murray-Close D, et al. Physical activity, sadness, and suici-
dality in bullied US adolescents. J Am Acad Child Adolesc Psychiatry 2015;
54(10):808–15.
15. Seligman MEP. Authentic happiness: using the new positive psychology to realize
your potential for lasting fulfillment. New York: Free Press; 2002.
16. Taliaferro LA, Rienzo BA, Pigg RM Jr, et al. Associations between physical activity
and reduced rates of hopelessness, depression, and suicidal behavior among
college students. J Am Coll Health 2009;57(4):427–36.
17. Stavrakakis N, de Jonge P, Ormel J, et al. Bidirectional prospective associations
between physical activity and depressive symptoms. The TRAILS Study.
J Adolesc Health 2012;50(5):503–8.
18. Hoza B, Martin CP, Pirog A, et al. Using physical activity to manage ADHD symp-
toms: the state of the evidence. Curr Psychiatry Rep 2016;18(12):113.
19. Rommel AS, Lichtenstein P, Rydell M, et al. Is physical activity causally associ-
ated with symptoms of attention-deficit/hyperactivity disorder? J Am Acad Child
Adolesc Psychiatry 2015;54(7):565–70.
20. Terry-McElrath YM, O’Malley PM, Johnston LD. Exercise and substance use
among American youth, 1991-2009. Am J Prev Med 2011;40(5):530–40.
21. Koivukangas J, Tammelin T, Kaakinen M, et al. Physical activity and fitness in ad-
olescents at risk for psychosis within the Northern Finland 1986 Birth Cohort.
Schizophr Res 2010;116(2–3):152–8.
22. Cote AT, Devlin AM, Panagiotopoulos C. Initial screening of children treated with
second-generation antipsychotics points to an association between physical ac-
tivity and insulin resistance. Pediatr Exerc Sci 2014;26(4):455–62.
23. Vopat BG, Klinge SA, McClure PK, et al. The effects of fitness on the aging pro-
cess. J Am Acad Orthop Surg 2014;22(9):576–85.
24. Lubans D, Richards J, Hillman C, et al. Physical activity for cognitive and mental
health in youth: a systematic review of mechanisms. Pediatrics 2016;138(3) [pii:
e20161642].
25. GBD 2015 Obesity Collaborators, Afshin A, Forouzanfar MH, Reitsma MB, et al.
Health effects of overweight and obesity in 195 countries over 25 years. N Engl
J Med 2017;377(1):13–27.
26. Sartori SB, Whittle N, Hetzenauer A, et al. Magnesium deficiency induces anxiety
and HPA axis dysregulation: modulation by therapeutic drug treatment. Neuro-
pharmacology 2012;62(1):304–12.
27. Torabi M, Kesmati M, Harooni HE, et al. Effects of nano and conventional zinc ox-
ide on anxiety-like behavior in male rats. Indian J Pharmacol 2013;45(5):508–12.
28. Kiecolt-Glaser JK, Belury MA, Andridge R, et al. Omega-3 supplementation
lowers inflammation and anxiety in medical students: a randomized controlled
trial. Brain Behav Immun 2011;25(8):1725–34.
29. Jacka FN, Cherbuin N, Kaarin J, et al. Western diet is associated with a smaller
hippocampus: a longitudinal investigation. BMC Med 2015;13:215.
30. Pina-Camacho L, Jensen SK, Gaysina D, et al. Maternal depression symptoms,
unhealthy diet and child emotional-behavioural dysregulation. Psychol Med
2015;45(9):1851–60.
31. Steenweg-de Graaff J, Tiemeier H, Steegers-Theunissen RP, et al. Maternal die-
tary patterns during pregnancy and child internalising and externalising prob-
lems. The Generation R Study. Clin Nutr 2014;33(1):115–21.
Promoting Mental Health and Wellness 21
32. Jacka FN, Ystrom E, Brantsaeter AL, et al. Maternal and early postnatal nutrition
and mental health of offspring by age 5 years: a prospective cohort study. J Am
Acad Child Adolesc Psychiatry 2013;52(10):1038–47.
33. Khalid S, Williams CM, Reynolds SA. Is there an association between diet and
depression in children and adolescents? A systematic review. Br J Nutr 2017;
116(12):2097–108.
34. Jacka FN, Kremer PJ, Berk M, et al. A prospective study of diet quality and
mental health in adolescents. PLoS One 2011;6(9):e24805.
35. McMartin SE, Kuhle S, Colman I, et al. Diet quality and mental health in subse-
quent years among Canadian youth. Public Health Nutr 2012;15(12):2253–8.
36. Jacka FN, Rothon C, Taylor S, et al. Diet quality and mental health problems in
adolescents from East London: a prospective study. Soc Psychiatry Psychiatr Ep-
idemiol 2013;48:1297–306.
37. Trapp GS, Allen KL, Black LJ, et al. A prospective investigation of dietary patterns
and internalizing and externalizing mental health problems in adolescents. Food
Sci Nutr 2016;4(6):888–96.
38. Winpenny EM, van Harmelen AL, White M, et al. Diet quality and depressive
symptoms in adolescence: no cross-sectional or prospective associations
following adjustment for covariates. Public Health Nutr 2018;21(13):2376–84.
39. Lai JS, Hiles S, Bisquera A, et al. A systematic review and meta-analysis of die-
tary patterns and depression in community-dwelling adults. Am J Clin Nutr 2014;
99(1):181–97.
40. Psaltopoulou T, Sergentanis TN, Panagiotakos DB, et al. Mediterranean diet,
stroke, cognitive impairment, and depression: a meta-analysis. Ann Neurol
2013;74:580–91.
41. Jacka FN, O’Neil A, Opie R, et al. A randomized controlled trial of dietary
improvement for adults with major depression (the ‘SMILES’ trial). BMC Med
2017;15:23.
42. Shivappa N, Hebert JR, Tehrani AN, et al. A pro-inflammatory diet is associated
with an increased odds of depression symptoms among Iranian female adoles-
cents: a cross-sectional study. Front Psychiatry 2018;9:400.
43. Moylan S, Berk M, Dean OM, et al. Oxidative & nitrosative stress in depression:
Why so much stress? Neurosci Biobehav Rev 2014;45C:46–62.
44. Murphy T, Dias GP, Thuret S. Effects of diet on brain plasticity in animal and hu-
man studies: mind the gap. Neural Plast 2014;2014:563160.
45. Akbaraly T, Sexton C, Zsoldos E, et al. Association of long-term diet quality with
hippocampal volume: longitudinal cohort study. Am J Med 2018;131(11):
1372–81.e4.
46. Cryan JF, Dinan TG. Mind-altering microorganisms: the impact of the gut micro-
biota on brain and behaviour. Nat Rev Neurosci 2012;13(10):701–12.
47. Valdes AM, Walter J, Segal E, et al. Role of the gut microbiota in nutrition and
health. BMJ 2018;361:k2179.
48. Cerdo T, Ruiz A, Suarez A, et al. Probiotic, prebiotic, and brain development. Nu-
trients 2017;9(11):1247.
49. Dash S, Clarke G, Berk M, et al. The gut microbiome and diet in psychiatry: focus
on depression. Curr Opin Psychiatry 2015;28(1):1–6.
50. David LA, Maurice CF, Carmody RN, et al. Diet rapidly and reproducibly alters the
human gut microbiome. Nature 2014;505:559–63.
51. De Filippo C, Cavalieri D, Di Paola M, et al. Impact of diet in shaping gut micro-
biota revealed by a comparative study in children from Europe and rural Africa.
Proc Natl Acad Sci U S A 2010;107:14691–6.
22 Hosker et al