Learning Activity Sheet General Chemistry 1: Empirical Formula and Molecular Formula

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LEARNING ACTIVITY SHEET

GENERAL CHEMISTRY 1

I. Title: Empirical and Molecular Formula


II. Learning Competencies:
a. Calculate the empirical formula from the percent composition of a compound
(STEM_GCPCIf-32)
b. Calculate the molecular formula given molar mass
(STEM_GCPCIf-33)
III. Activities:
Activity 1: Classifying Exponential Function, Exponential Equation and Exponential Inequalities.
Objectives: At the end of this activity the learners must be able to:
1. Know some concepts about empirical and molecular formula.
2. Classify the given as empirical or molecular formula.
3. Write the empirical and molecular formula of some compounds.
Input:

Empirical Formula and Molecular Formula


The simplest, or empirical formula for a compound is the smallest whole-
number ratio of atoms present. For molecular compounds the molecular formula
indicates the actual numbers of atoms present in a molecule of the compound. It
may be the same as the simplest formula or else some whole-number multiple of
it.
For example, the molecular formula of glucose is C6H12O6 which can be further
simplified to CH2O, which is its empirical formula. Also, the simplest and
molecular formulas for water are both H2O; however, for hydrogen peroxide, they
are HO and H2O2, respectively. Each year thousands of new compounds are made
in laboratories or discovered in nature.
One of the first steps in characterizing a new compound is the determination
of its percent composition. A qualitative analysis is performed to determine which
elements are present in the compound. Then a quantitative analysis is performed
to determine the amount of each element.
Once the percent composition of a compound (or its elemental composition by
mass) is known, the simplest formula can be determined.

Output 1:
Directions: Determine whether the following statements are true or false. Put if the
statement is true and if the statement is false in the space provided before each item.

_______1. Empirical formula represents the simplest whole-number ratio of moles of each element in
the compound.

_______2. Molecular formula shows the exact or actual number of different number of atoms in a
compound.
_______3. There is no such compound that has the same molecular and empirical formula.

_______4. Some compounds have the same empirical formula.

_______5. Molecular formula mass is needed in calculating molecular formula.

Output 2:
Direction: Identify if the given formulas of compounds are in molecular or empirical formula. Write
“MF” if molecular and “EF” if the given is empirical at the space provided.

_______1. P2O5 _______2. N2O4 _______3. C10H22

_______ 4. Na2S2O3 _______5. NaClO4

Output 3.
Directions: Complete the table by filling out the missing molecular or empirical formula of the given
compound. Write the letter in the space provided. For example,
COMPOUND MOLECULAR FORMULA EMPIRICAL FORMULA
Hydrogen peroxide H2O2 HO

COMPOUND MOLECULAR FORMULA EMPIRICAL FORMULA


Water 1._______________ 2.________________

Glucose 3._______________ CH2O

Oxalic acid H2C2O4 4.________________

Ethanol 5._______________ C2H6O

Activity 1: Calculating empirical and molecular formula


Objectives: At the end of this activity the learners must be able to:
1. Calculate empirical formula from the percent composition.
2. Calculate molecular formula given molar mass.
Input:

EMPIRICAL FORMULA
1. Convert the mass percent to actual mass by assuming 100 g of the compound.
2. Convert the identified masses to moles by using the molar mass of the elements involved.
3. Express moles as simplest ratio by dividing the moles by the smallest. This will serve as
their subscript.
4. When necessary, multiply the subscripts by 2, 3 or 4 or any other smallest whole number
that will make the subscripts free of fractions.
MOLECULAR FORMULA
1. Find the empirical formula and determine its formula mass
2. Divide the given formula mass by the empirical formula mass
3. Multiply the subscripts of the empirical formula by the result found in step 2.
Output 1:
Directions: Perform the following steps indicated and make sure to write your answer following
these steps in the space provided.

Output 2:
Directions: Work the following problems. Show your solutions neatly in a separate sheet of paper.

1. During excessive physical activity, lactic acid (Molar mass = 90.08 g/mol) forms in muscle tissue
and is responsible for muscle soreness. Elemental analysis shows that this compound contains 40.0
mass % C, 6.71 mass % H and 53.3 mass % O. Determine the empirical and molecular formula of
lactic acid.

SOLUTION
:
2. A compound is found to consist 43.64% P and 56.36% O. The molar mass for the compound is
283.88 g/mol. What is the empirical formula and molecular formula of the compound?

SOLUTION
:

IV. Generalization
You encountered concepts on empirical and molecular formula. Now it’s time to pause for a
while and reflect to your learning process by doing the 3-2-1 chart.

What are the 3 most important things you have learned?

What are the two things you are not sure about?

What is that one thing you want to clarify immediately?

V. References
General Chemistry 1 Teacher’s Guide pp. 79-81
Martin S. Silberberg, Principles in General Chemistry (New York: Mc Graw Hill, 2007), 77-81.

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