REPUBLIC of the PHILIPPINES

City of Makati
COLLEGE OF ALLIED HEALTH STUDIES
J. P. Rizal Extension, West Rembo, Makati City 1215
Telephone No. : (+632) – 881 – 1571
_____________________________________________________________________________________
DRUG STUDY
Drug Name Mechanism of Action Indication Side Effects/Adverse Contraindication Nursing Consideration
Effect
Unknown. Thought to directly  To induce or CNS:seizures,coma,neo  Hypersensitivity Before:
Generic Name: stimulate smooth muscle stimulate labor natal brain to drug  Inform patient about risks and benefits of oxytocin-
oxytocin contractions in uterus and  To control damage,subarachnoid  Cephalopelvic induced labor.
cervix. postpartum hemorrhage disproportion  Teach patient to recognize and immediately report
Brand Name: bleeding CV: premature  Fetal distress adverse drug effects.
Pitocin,Syntocinon ,  Incomplete abortion ventricular when delivery is
Syntometrin contractions,arrhythmia During:
not imminent
Classification s,neonatal bradycardia
Pharmacologic
 Prolonged use in
GI:nausea,vomiting uterine inertia or  Continuously monitor contractions,fetal and
class: Posterior GU:postpartal
pituitary hormone severe toxemia maternal heart rate, and maternal blood pressure
hemorrhage;pelvic  Hypertonic or and ECG. Discontinue infusion if uterine
Therapeutic class:
Uterine-active agent hematoma;uterine hyperactive hyperactivity occurs.
Pregnancy risk hypertonicity, spasm,or uterine pattern  Monitor patient extremely closely during first and
category NR tetanic  Unfavorable fetal second stages of labor because of risk of cervical
contraction;abruptio position or laceration, uterine rupture,and maternal and fetal
placentae;uterine presentation death.
Dosage: rupture (with excessive that’s After:
Injection: 10 Reference: Stimson, J. C. doses) undeliverable  Assess fluid intake and output.Watch for signs and
units/ml ampule or (1921). Nurses Hand-Book of Hematologic:afibrinogen without symptoms of water intoxication.
vial, IM Drugs and Solutions. The emia conversion  When giving drug to control postpartal
American Journal of Nursing, Hepatic:neonatal
 Labor induction or bleeding,monitor and record vaginal bleeding.
21(6),pg. 936-937 jaundice Other:
augmentation
hypersensitivity
when vaginal
reactions including
delivery is
anaphylaxis,low 5-
 REPUBLIC of the PHILIPPINES
City of Makati
COLLEGE OF ALLIED HEALTH STUDIES
J. P. Rizal Extension, West Rembo, Makati City 1215
Telephone No. : (+632) – 881 – 1571
_____________________________________________________________________________________
DRUG STUDY
minute Apgar score contraindicated
(neonate) (as in invasive
cervical cancer,
active genital
herpes,or total
placenta previa)

Reference:Stimson, J. C. (1921). Nurses Hand-Book of Drugs and Solutions. The American Journal of Nursing, 21(6),pg. 936-937
 REPUBLIC of the PHILIPPINES
City of Makati
COLLEGE OF ALLIED HEALTH STUDIES
J. P. Rizal Extension, West Rembo, Makati City 1215
Telephone No. : (+632) – 881 – 1571
_____________________________________________________________________________________
DRUG STUDY
Drug Name Mechanism of Action Indication Side Effects/Adverse Contraindication Nursing Consideration
Effect
Generic Name: Acts as competitive inhibitor at  Preanesthetic CNS:  Hypersensitivity Before:
scopolamine postganglionic muscarinic sedation and drowsiness,dizziness,co to scopolamine,  Tell patient transdermal patch is most effective if
hydrobromide (hyoscine receptor sites of obstetric amnesia nfusion, other belladonna applied to dry skin behind ear 4 hours before
hydrobromide) parasympathetic nervous  Postoperative restlessness,fatigue alkaloids,or traveling.
Brand Name: system and on smooth muscles nausea and CV: tachycardia,palpitat barbiturates  Caution patient to avoid touching exposed
Buscopan ,Kwells that respond to acetylcholine but vomiting ions,hypotension,transie  Hypersensitivity adhesive layer of transdermal patch.
Classification: lack cholinergic innervation.May  Motion sickness nt heart rate changes to bromides  Advise patient to wash and dry hands thoroughly
Pharmacologic class: block cholinergic transmission EENT: blurred (injection only) before and after applying patch.
Antimuscarinic, from vestibular nuclei to higher vision,mydriasis,photop  Angle-closure During:
belladonna alkaloid CNS centers and from reticular hobia,conjunctivitis glaucoma  If patch becomes dislodged,instruct patient to
Therapeutic class: formation to vomiting center. GI: constipation,dry  Acute remove it and apply new patch on a different site
Antiemetic,antivertigo mouth hemorrhage behind ear.
agent,anticholinergic GU: urinary hesitancy or  Myasthenia  Tell patient that using patch for more than 72 hours
Pregnancy risk category retention gravis may cause withdrawal symptoms
C Skin: decreased  Obstructive (headache,nausea,vomiting,dizziness).Advise him
sweating,rash uropathy to limit use when feasible.
(including  Inform patient that his eyes may be markedly
Dosage: prostatic sensitive to light during patch use.Instruct him to
Injection: 1 mg/ml in 1- hypertrophy) wear sunglasses and use other measures to guard
ml vials, 0.4 mg/ml in
 Obstructive GI eyes from light.
0.5-ml ampules and 1-
disease (including  Caution patient to avoid alcohol because it may
ml vials,0.86 mg/ml in
paralytic ileus and increase CNS depression.
0.5-ml ampules
intestinal atony) After:
Transdermal system Reference: Stimson, J. C.
 Reflux  Assess vital signs and neurologic,
(Transderm-Scop): 1.5 (1921). Nurses Hand-Book of
 REPUBLIC of the PHILIPPINES
City of Makati
COLLEGE OF ALLIED HEALTH STUDIES
J. P. Rizal Extension, West Rembo, Makati City 1215
Telephone No. : (+632) – 881 – 1571
_____________________________________________________________________________________
DRUG STUDY
mg/patch (releases 0.5 Drugs and Solutions. The esophagitis cardiovascular,and respiratory status.
mg scopolamine over 3 American Journal of Nursing,  Monitor patient for urinary hesitancy or retention.
days) 21(6),pg. 936-937

Reference: Stimson, J. C. (1921). Nurses Hand-Book of Drugs and Solutions. The American Journal of Nursing, 21(6),pg.1195-96