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I. Drug Study: Denosuma B Natalizuma B, Roflumilast

Gentamicin sulfate is an IV antibiotic used to treat serious infections caused by sensitive strains of bacteria. It works by inhibiting protein synthesis through binding to the 30S ribosomal subunit. Potential adverse effects include CNS issues, ototoxicity, nephrotoxicity and hematologic effects. Nursing responsibilities when administering gentamicin include skin testing, monitoring hearing and renal function, obtaining blood levels, and watching for signs of superinfection or toxicity. Therapy typically continues for 7-10 days before evaluating response with new cultures and sensitivity testing.
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0% found this document useful (0 votes)
48 views

I. Drug Study: Denosuma B Natalizuma B, Roflumilast

Gentamicin sulfate is an IV antibiotic used to treat serious infections caused by sensitive strains of bacteria. It works by inhibiting protein synthesis through binding to the 30S ribosomal subunit. Potential adverse effects include CNS issues, ototoxicity, nephrotoxicity and hematologic effects. Nursing responsibilities when administering gentamicin include skin testing, monitoring hearing and renal function, obtaining blood levels, and watching for signs of superinfection or toxicity. Therapy typically continues for 7-10 days before evaluating response with new cultures and sensitivity testing.
Copyright
© © All Rights Reserved
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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I.

DRUG STUDY

Dosage, Drug-to-
Contra- Mechanism Adverse Nursing
Name of Drug Route and Indication Drug
indication of Action Effects Responsibility
Frequency Interaction
Generic Name: IV 15mg q Serious Contraindicat Inhibits Denosuma CNS: fever, > Do skin testing
12hr infections ed in patients protein b: headache, before
Gentamicin Sulfate caused by hypersensitiv synthesis by natalizuma lethargy, administering the
Brand Name: sensitive e to drug or binding b, seizures, drug.
strains of other directly to roflumilast: vertigo, > Evaluate
Cidomycin, Pseudomo aminoglycosi the 30S May dizziness patient’s hearing
Garamycin nas des ribosomal increase EENT: before and during
Therapeutic aeruginosa subunit; risk of ototoxicity, therapy, report if
Classification: , E. Coli, bactericidal serious blurred there are
Proteus, infection. vision, alterations in the
Antibiotics Klebsiella, Consider tinnitus hearing process.
or therapy GI: Nausea > Weigh patient
Staphylocc modification and and review renal
ocus . vomiting function studies
Leflunomid GU: before therapy
e: May nephrotoxici begins.
increase ty > Obtain blood
risk of Hematologic peak gentamicin
hematologic : anemia, level 1 hour after
toxicity, leukopenia, I.M injection
such as thrombocyto > Watch signs
pancytopeni penia, and symptoms of
a, agranulocyt superinfection.
agranulocyt osis > Therapy usually
osis, or Respiratory: continues for 7 to
thrombocyt apnea 10 stop therapy
openia. Skin: rash, and obtain new
Live - virus urticaria, specimens for
vaccines: pruritus culture and
Immunosup Other: sensitivity testing.
pressants anaphylaxis
may
enhance
adverse or
toxic effect
of live-virus
MEDICATION
vaccines.
TICKET:
Pimecrolim
us,
tacrolimus
(topical):
May
enhance
adverse or
toxic effect
of
immunosup
pressants.
Tofacitinib:
May
enhance
immunosup
pressive
effect of
tofacitinib.
Trastuzuma
b: May
enhance
neutropenic
effect of
immunosup
pressants.

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