Health Management
Health Management
Health Management
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The best fed and housed stock with the best genetic potential will not grow
and produce efficiently if they become diseased or infested with parasites.
Therefore good poultry health management is an important component of
poultry production. Infectious disease causing agents will spread through a
flock very quickly because of the high stocking densities of commercially
housed poultry.
For poultry health management to be effective a primary aim must be to
prevent the onset of disease or parasites, to recognise at an early stage
the presence of disease or parasites, and to treat all flocks that are
diseased or infested with parasites as soon as possible and before they
develop into a serious condition or spread to other flocks. To be able to do
this it is necessary to know how to recognise that the birds are diseased,
the action required for preventing or minimising disease and how to monitor
for signs that the prevention program is working.
Disease
A disease is any condition that interferes with the normal functioning of the
cells, tissues, organs and the whole body systems. Diseases of poultry
have many causes and include:
1. Deficiencies of essential nutrients such as vitamins, minerals or other
nutrients.
2. The consumption of toxic substances such as poisons.
3. Physical damage e.g. environmental extremes and injury.
4. Internal and external parasite infestations such as lice and worms.
5. Infectious disease caused by micro-organisms such as bacteria and
viruses.
Diseases that result from nutrient deficiencies, consumption of toxic
substances and physical damage are referred to as non-infectious
diseases. These diseases cannot be passed from bird to bird and members
of the flock must share a common experience for individuals to contract
these non-infectious diseases. In the widest sense, infectious diseases are
caused by microorganisms that include parasites, fungi, protozoa, bacteria,
mycoplasmas, chlamydia and viruses. These diseases are often also called
contagious diseases meaning that they can be passed from one bird to
another either directly or indirectly.
Direct transmission occurs when one diseased bird passes the cause of
the disease via direct contact to a susceptible healthy bird. Such passage
may be horizontal transmission (from one bird to another) or vertical
transmission (from parent to offspring) via the egg or sperm either inside
the egg or on the shell. Indirect transmission occurs when the causal
organism is passed from one bird to another via an intermediate host such
as insects, earthworms, snails or slugs, wild birds or animals or some other
object such as equipment, food or water, vehicles, people, respiratory
droplets, litter or faeces.
Viruses
Bacteria
Fungi
Protozoa
Internal parasites
External parasites
Viruses
Viruses are the smallest pathogens and can only be seen through an
electron microscope. Viruses consist of an outer layer/s surrounding
special protein material similar to the genetic material of the cells they
invade. They can multiply and do harm only when inside the animal cell
and if they invade and damage enough cells, the animal can show signs of
that infection.
Antibiotics and other medications as a rule do not affect viruses and, as a
consequence, there are very few medications that can treat diseases
caused by viruses, although there are times when a drug may be used to
control secondary infections. The best way to manage diseases caused by
viruses is by quarantine and good hygiene to lower the challenge, and
vaccination to maximise the birds’ immunity to future challenges. Some
have the ability to survive for very long periods of time in the bird dander
and feather debris, litter and manure, insects and rodents.
Bacteria
Bacteria are single cell organisms with a nucleus and multiply by simple
fission, which means that one divides into two, and some can do this very
quickly inside the host or in a suitable environment. Some are very fragile
and do not survive long outside of the host while others may survive for
long periods even in a harsh environment. Many have the ability to turn into
spores by forming a very tough wall that protects them from most of the
materials used to kill them. These types of bacteria are much more
susceptible to these compounds when not in the spore form.
Bacteria may be described as being gram positive or gram negative. This
characteristic is to do with differences in their cell walls that affects their
staining for viewing under the microscope. Whether they are one or the
other also influences their response to certain chemicals, including
disinfectants.
Different types of bacteria harm the birds in two predominant ways:
1. Those that attack and damage the birds’ cells or spaces between the
cells.
2. Those that produce toxins or poisons that harm the birds.
There are several antibiotics and other drugs that are effective against
different bacteria. However, quarantine and good hygiene that lower the
numbers to be targeted by the drugs are the important first lines of defense
against these organisms.
Chlamydia
Chlamydia are a little larger than viruses. They live inside the cells they
infect particularly in the cells of the respiratory system. They can be treated
with antibiotics.
Mycoplasmas
These are single cell organisms slightly larger than chlamydia. They have a
cell wall and nucleus. The most commonly known disease caused by this
organism is Mycoplasmosis or Chronic Respiratory Disease (CRD) caused
by Mycoplasma gallisepticum. Diseases caused by Mycoplasma organisms
respond to some antibiotics. These organisms do not survive long outside
of the host and good quarantine and hygiene procedures coupled with a
suitable house de-population period will provide good control.
Fungi
Fungi are organisms larger than bacteria and are considered to be
members of the plant kingdom. They multiply by forming spores that are
released and enter the local environment. When conditions are satisfactory
the spores start to grow to repeat the cycle.
Fungi harm the birds in two ways:
1. By being taken into the body e.g. in the respiratory system where they
start to grow.
2. By producing toxins or poisons e.g. in the food. When the birds consume
the contaminated food the toxin affects them. A good example of this type
of damage is aflatoxin produced by certain moulds or fungi that commonly
grow in peanut meal and some litter materials. Moulds or fungi are
resistant to nearly all antibiotics.
Protozoa
Protozoa are single cell organisms larger than bacteria. Protozoa have a
complex reproduction system that, in many cases, allows them to multiply
into extremely high numbers very quickly. A good example of protozoan
diseases is coccidiosis of poultry.
Protozoa generally harm the birds by destroying tissue. A number of
chemicals have been developed that can be used to treat birds infected by
the different protozoans. Others have been developed that interfere with
the protozoan life cycle and may be used as preventive treatments while
the birds develop a natural immunity. These preventive drugs are often
referred to as coccidiastats.
Internal parasites
Parasites are organisms that live off the host. Internal parasites in poultry
are multi-celled organisms that live inside the bird usually located in
specific organs. Most internal parasites, and particularly those found in
Australia, are visible to the naked eye.
While there are many different internal parasites found in poultry, only three
are likely to cause harm. These are:
The thorough cleaning of poultry houses and equipment after each flock
has been removed.
The use of vehicle disinfection and wash facilities.
The use of foot baths at the entry to each house.
The provision of footwear at the entry to each shed.
The use of clean litter material after washing the shed and not re-using
litter. Litter in the poultry house should be managed to maintain it in a dry
friable state without caking or being too wet.
Removing all dead birds daily and disposing them in a recommended
manner.
Maintaining all houses and ancillary buildings and surrounds in a clean
and tidy state.
Resisting disease
There are a number of factors that influence whether a bird will succumb to
a disease. These include:
Disease severity
From the point of view of flock health management, disease in poultry may
be one of two levels of severity:
Sub-clinical: a sub-clinical disease is one where the signs are not obvious.
The birds do not appear to be sick but the infection causes slower growth
and/or lower egg production. Sub-clinical disease may predispose to
secondary invasion by other organisms. The only evidence that the birds
are infected is the lower production efficiency found on an analysis of
performance. In many cases this is not found until much of the financial
damage has been done.
Clinical: a clinical disease is one where the signs that the birds are sick
are more obvious. They show the clinical signs typical of the disease with
which they are infected. Clinical disease not only affects the performance
of the flock but, in many cases, a number of the birds die or never recover
to their previous performance level and remain unthrifty.
In each case, affected birds and in many cases recovered birds, are
carriers that may be a source of infection for other stock with which they
have contact and may transfer the causal organism either directly or
indirectly to other stock not involved in this particular outbreak.
Vaccination
Vaccination is aimed at triggering the birds immune system to produce
antibodies to fight infection. While not all diseases can be vaccinated
against, all potential infectious disease threats should be identified and a
suitable vaccination program developed to help combat those that can.
Veterinary advice may be necessary to design a suitable vaccination
program for each farm.
The keys to effective vaccination are:
The potency of the vaccine used and/or its suitability for the disease strain
to be controlled.
The handling and storage procedures for the vaccine during travel and on
the farm.
The use of the recommended application techniques.
The adherence to the recommended program.
Preventative medication
Vaccines are not available to combat all disease threats. It may be
necessary to use a preventive medication to combat infection by some
organisms. Veterinary advice may be necessary to determine an
appropriate preventive medication program.
Monitoring program
It is not possible to see most infectious agents. Therefore, it is appropriate
to have a monitoring program. This may consist of:
1. Daily checks of the flock.
2. Regular on-farm and laboratory autopsies.
3. Blood sampling for laboratory analysis.
4. Exposing plates and taking swabs for laboratory analysis.
These techniques can be used to monitor the current disease situation
including the presence of parasites, the success or failure of cleaning
procedures and the success or failure of vaccinating procedures.
Light control
Chickens have colour vision and different colours and light levels affect chicken
behaviour. Green and blue light improves growth and lowers age at sexual maturity,
while red, orange and yellow light increases age at sexual maturity and red and
orange light increase egg production. Birds are calmer in blue light. For many years
it was practice to brood and rear chickens under red light to prevent cannibalism,
based on the concept that red light makes it difficult for a potentially cannibalistic bird
to see red blood vessels and blood on other birds. Currently, the most useful method
to prevent feather pecking and cannibalism is to house birds under very dim white
light. The birds cannot see each other well which is thought to reduce aggressive
behaviour among them. This requires light proof shedding, however low light levels
can cause eye abnormalities.
Use of devices to restricting vision and beak use
The use of spectacles (fitted to the nares of birds) controls feather pecking. It only
allows birds to look to the side or down but not directly ahead. Spectacles can only
be put on birds of pullet size or larger, cannot be used in cages and are easily
dislodged. Red contact lenses have been used for layers as an alternative to beak-
trimming. They cause eye irritation, eye infections, and abnormal behaviour and are
not retained well. Bitting devices have been developed for use in game birds, which
are held in place by lugs inserted in the nares. The use of fitted devices as a
preventative measure against feather pecking is not permitted in many countries.
Environmental enrichment
Environmental enrichment aims to increase desirable behaviours, reduce harmful
ones, sustain the birds’ long-term interest, and enable them to cope with challenges.
Enrichment involves increasing environmental complexity to encourage birds to
interact with their environment.
Nutrition
The main strategy to prevent feather pecking is to provide an adequate substrate.
Substrate conditions during the rearing period affect the development of feather
pecking. Use of scratch grain is recommended. During the rearing period, placing
semi-solid milk blocks in the house, hanging green leafy vegetables and spreading
grass clippings can prevent feather pecking. An adequate amount of insoluble fibre
in the layer diet is important for minimising the outbreak of cannibalism in chickens.
Millrun, oat hulls, rice hulls and lucerne meal are effective sources of fibre. The
physical properties of the fibre modulate the function of the gizzard making the birds
calmer. Providing adequate calcium, manganese, arginine, zinc, protein, sulphur
amino acids (methionine and cysteine), trytophan, B group vitamins, thiamine and
dietary electrolytes minimises pecking mortality.
Beak abrasives
Abrasive materials applied to the feed trough may enable the bird to blunt the
hooked end of the beak while feeding and reduce the effectiveness of pecking. The
beak blunting technique can be applied to growing pullets and during the laying
period. Utilising the blunting procedure early in the rearing period may prevent the
formation of the hooked end of the beak.
Summary
When birds are not beak trimmed, increased incidences of mortality and morbidity
will occur due to cannibalism. Welfare problems associated with cannibalism can be
devastating. When performed correctly to industry standards, beak trimming has
advantages. These include reduced:
Feather pecking
Mortality
Vent pecking and prolapse
Bullying
Stress on the bird
When beak trimming is not done correctly, birds can suffer from:
1. Reduced ability to eat and drink
2. Short and long term stress
3. Reduced social status
There are production techniques which may reduce the need for beak trimming,
although none of these can guarantee against an outbreak of damaging pecking and
cannibalism. These techniques include:
Light control
Devices to restrict vision
Devices to restrict beak use
Environmental enrichment
Anti-pick compounds
Nutritional amendments
Beak abrasives
General husbandry
Healthy, unstressed birds have an active metabolism and effective immune
system to protect them against disease. Feeding birds appropriately with a
nutritionally balanced diet, maintaining a comfortable living environment
and minimising fear and anxiety in the birds will help the bird’s natural
protective mechanisms to function optimally.
Stock selection
Different genetic lines of poultry may vary in their ability to resist or recover
from some diseases. The choice of genetic lines resistant to disease
problems that have been known to occur in a particular poultry operation
can substantially reduce the costs of disease and other disease prevention
techniques.
Vaccination
Vaccines aid in preventing disease by stimulating the bird’s immune
system in such a way that it enhances the immune response when the bird
is subsequently exposed to a pathogen (or disease-causing organism).
Classically, vaccines have either contained a small live dose of a weak
form of the pathogen or a larger dose of a killed preparation of the disease-
causing organism. The weak forms of pathogens used in live vaccines can
either be naturally occurring or can be developed in a laboratory. If they
have been developed they are called attenuated vaccines. Live vaccines
tend to give longer immunity than killed vaccines because the live organism
can colonise and survive in the host for some time and stimulate a longer
and more effective immune response. New technologies are leading to
improved methods of developing vaccines. These include more efficient
methods for identifying the ways organisms cause disease and stimulate
an immune response in the host, as well as highly specific and effective
attenuation procedures.
Scientists are developing a vaccine for avian influenza (Birds showing symptoms) Source: CSIRO
Types of vaccine
Live vaccine – the active part of the vaccine is the live organism that
causes the disease. As such, it is capable of inducing the disease in birds
that have not had previous contact that organism. Vaccinated birds, in
many cases are able to infect non-vaccinated birds if housed together.
Attenuated vaccine – with this type of vaccine the organism has been
weakened by special procedures during manufacture so that it has lost its
ability to cause the serious form of the disease. At worst, the birds may
contract a very mild form of the disease, however, the vaccine still has the
ability to trigger the immune system to produce antibodies.
Killed vaccine – with this type of vaccine the organism has been killed and
is unable to cause the disease, although the ability to trigger the immune
system remains. In many cases, the level of immunity produced by this
form of vaccine is weaker than that produced by live and attenuated
vaccines.
Vaccine production
Vaccines are produced mainly in three forms:
1. Liquid vaccine – it is in fluid form ready to use.
2. Freeze dried vaccine – the vaccine is stored as one pack of freeze dried
material and one pack of diluent, often a sterile saline solution. These
have to be combined before use.
3. Dust – where the vaccine is prepared for administration in the dry form.
Vaccines are sold in dose lots, the number of doses being the number of
fowls that may be vaccinated with that amount of vaccine when using the
recommended technique. In the case of many vaccines there are
differences in the disease organism strains that they are effective against.
It is important that the correct vaccine strain be used and this can only be
determined by veterinary advice.
Vaccination procedures
There are a number of ways that vaccines may be administered to poultry
and it is very important that the correct method be used for each vaccine.
To use the wrong method will often result in failure of the vaccine to
produce the desired immunity. Some of the methods require the operator to
handle every bird and, consequently are time consuming and stressful to
the birds and operator. Other methods involve administration by methods
much less stressful and time consuming. These methods include
administration via the drinking water or as an aerosol spray. The different
ways that the vaccines may be administered to poultry are below.
In-ovo vaccination
Using the method of in-ovo vaccination, the vaccine is administered into
the embryo before hatch.
In general, vaccines can be applied to five different areas of the egg: the air
cell, the allantoic sac, the amniotic fluid, the body of embryo and the yolk
sac. Vaccine uptake and therefore the immune response of the chicken
depend largely on the area of injection. While injection in the air cell has
been shown to be minor/not effective, injection in the body of the embryo or
the allantoic sac is effective. Therefore, the optimum period to inject the
embryo is in the late stage of development, i.e. the time between the
ascendance of the stalk of the yolk sac into the abdomen (about the time
when the chicken tucks its head under its wings) and external pipping.
During that late stage of development, the embryo is mature enough to
cope with the viral stimulus and the trauma induced by the penetrating
needle is unlikely to cause severe tissue damage. Signs of too early
vaccination include reduced hatchability, late death and increased number
of culled birds. However, if vaccination is done too late in embryonation,
the risk of egg shell breakage is significantly higher. Therefore, in
ovo vaccination is commonly performed between days 18-19 of incubation.
The system of a larger outer needle (penetrating the egg shell) that
contains an inner needle (penetrating the embryo) enables for strong but
careful penetration of the egg and minimizes trauma to the embryo. In
addition, the use of two needles reduces the likelihood of transferring
contaminants on the outer egg shell into the sterile embryo. The needle for
punching the egg shell should not penetrate the embryonic cavity (the inner
shell membrane, the chorio-allantoic membrane or air cell membrane).
While the penetration of the outer egg shell increased the relative pore
volume about 30%, the risk for increased gas exchange of the embryo
occurs.
Hygiene management including reduced air circulation, well maintained air
filters, adjustment to weather conditionsand well maintained hatchery
insulation has to be taken into account when performing in ovo inoculation.
Only strict management of these environmental factors can reduce the
likelihood of infections of the egg, especially with aspergillosis or other air-
borne pathogens. Continuous training of reliable staff is of highest priority
to prevent reduced hatchability and to maintain high hygienic standards. A
sterile environment and the usage of chlorine based sanitizers are crucial.
The storage and preparation of the vaccine in a separate biosecure area as
well as strict precautions in using sterile devices such as containers and
water should be implemented. While the cost of machine acquisition is
high, the investment can pay back by its advantages.
The advantage of commencing immunity development before hatch can
prevent young chicks from early infection after hatch. Since high tech
machines are used for in ovo injection, the volume and concentration of the
vaccine to be administered are highly standardised, reducing human error
and labour cost when compared to vaccination of chickens later in life.
Furthermore, vaccination of every single chicken can be ensured resulting
in better uniformity of the flock. Coming with this is improved animal welfare
due to less handling of birds later in life.
Currently Marek’s disease, Newcastle disease, infectious laryngotracheitis
and infectious bursal disease vaccines are routinely administered using in
ovo vaccination in various countries. In ovo vaccination does not interfere
with maternal antibodies that may still present in the embryo. In fact, it
increases the level of immunity and as a consequence one injection is
sufficient to offer life-long protection against the target disease.
Intramuscular injection
This method involves the use of a hypodermic needle or similar equipment
to introduce the vaccine into the muscle (usually the breast muscle) of the
bird. The task is sped up greatly by the use of an automatic syringe which
makes the technique relatively easy and doesn’t harm the bird. Care must
be taken to ensure that the correct dose is administered to each chicken
and the equipment should be checked regularly to ensure this.
Care must be taken to ensure that the needle does not pass through into a
key organ and that other unwanted organisms are not administered to the
bird at the same time by contaminated vaccine or equipment.
Contamination can be prevented by good hygiene and vaccine handling
procedures.
Subcutaneous injection
This method involves the use of similar equipment to that used for the
intramuscular technique. The main difference between the two techniques
is that, in this case, the vaccine is injected under the skin, usually at the
back of the neck, and not into the muscle. Care must be taken to ensure
that the vaccine is injected into the bird and not just into the feathers or fluff
in the case of very young chickens. The dose being administered should be
checked for accuracy frequently. Maintain good hygiene practices to limit
introducing contaminating organisms during the procedure.
Ocular
This method involves the vaccine being put into one of the bird’s eyes.
From here the vaccine makes its way into the respiratory tract via the
lacrimal duct. The vaccine is delivered through an eyedropper and care
must be taken to ensure that the dropper delivers the recommended dose.
If it is too little, the level of immunity may be inadequate, while if too much,
the vaccine may not treat the total flock but will run out beforehand.
Nasal
This method involves introducing the vaccine into the birds’ nostrils either
as a dust or as a drop. Always ensure that the applicator delivers the
correct dose for the vaccine being used.
Oral
With this method the vaccine dose is given in the mouth. From here it may
make its way to the respiratory system or it may continue in the digestive
tract before entering the body.
Drinking water
With this method the vaccine is added to the drinking water and, as a
consequence, is less time consuming and is significantly less stressful on
the birds and operator. Take care to ensure the vaccine is administered
correctly as there is much scope for error. The recommended technique
observes the following:
Feather follicle
With this method the vaccine is introduced into the feather follicles (the
holes in the skin from where the feathers grow). The technique involves the
removal of a group of adjacent feathers or fluff in young chickens, and the
brushing of the vaccine into the empty follicles with a short, stiff bristled
brush. Good hygiene is necessary to prevent the introduction of
contaminant organisms with the vaccine.
Wing stab
With this method the vaccine is introduced into the wing by a special
needle(s). These needles have a groove along their length from just behind
the point. When dipped into the vaccine some of the vaccine remains on
the needle to fill the groove. The needle(s) are then pushed through the
web just behind the leading edge of the wing and just out from its
attachment to the body of the bird. Care must be taken to select a site free
of muscle and bone to prevent undue injury to the bird. Ensure that the
needles penetrate the layers of skin at the ideal site. A common problem is
for the vaccine to be brushed from the needles by fluff or feathers before it
is brushed into the follicles.
Spray
With this method the vaccine is sprayed onto the chickens (or into the air
above the chickens) using a suitable atomiser spray. The vaccine then falls
onto the chickens and enters the body of other chickens as they pick at the
shiny droplets of vaccine. A small quantity may be inhaled as well.
Monitoring
In the case of some vaccines, an important part of the procedure is to
ascertain whether the vaccine has worked, or “taken”. A good example of
this is fowl pox vaccine, which is administered by wing stab. Within 7 to 10
days after vaccination a “take” should appear at the vaccination site. This is
in the form of a small pimple one half to one centimetre in diameter. If the
take is larger and has a cheesy core, it indicates that contaminants have
been introduced either with the vaccine or with dirty vaccinating equipment.
A check for takes would involve inspecting approximately 100 birds for
every 10,000 vaccinated.
Another example of whether the birds are reacting satisfactorily to the
vaccination is the systemic reaction found in chickens vaccinated against
infectious bronchitis disease. In many cases the birds react approximately
5 to 7 days after vaccination by showing signs if ill health such as slight
cough, a higher temperature and lethargy. In cases where there are no
obvious signs of success, blood samples may be taken and sent to the
laboratory for examination. The usual test is for the presence of an
adequate number of the appropriate antibodies (called the titre) in the
blood. If the vaccination has been unsuccessful, it may be necessary to re-
vaccinate to obtain the desired protection.
Failure to find evidence of success could be because of:
Faulty technique resulting in the vaccine not being introduced into the
vaccination site.
Faulty vaccine – too old or not stored or mixed correctly. It would be
unusual but not impossible for the vaccine to be faulty from manufacture.
The birds are already immune i.e. the immune system has already been
triggered as a result of parental (passive) immunity, previous vaccination
or other exposure to the causal organism.
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