Pharm D POC Questions
Pharm D POC Questions
Pharm D POC Questions
QUESTION BANK
5. Which is having more boiling point; Dimethyl ether or ethanol? Give reasons.
9. Which of the following compounds would you predict to be able to form hydrogen
15. Explain why boiling point of water is more than ethanol and ethanol B.P is more than
acetone.
16. Write stability of carbanion.
CHAPTER 2: NOMENCLATURE OF ALIPHATIC AND AROMATIC ORGANIC
COMPOUNDS - 2 MARKS
CH3 CH3
CH3-CH-CH2-CH-CH3 CH3-C-CH2-CHO
CH2 CH3 CH3
30. Write the IUPAC names of acetic acid and acetone.
31. Give the common name and IUPAC name of (i) HCOOH (ii) HCHO
32. Name the following compounds(IUPAC): (i)(CH3)4C (ii)CH2=CH-CH2-CHO
33. Give the structural formulae for a)3-Methyl-1-penten-4-yen b)5-Hydroxy-3-hexenal
34. Give the IUPAC names for a)H2N-CH2-CH2-C-CH2-OH b) CH3-C-CH2-CH-COOH
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O O NO2
3. Define and classify free radicals. Describe orientation and stability of free radicals.
4. Discuss free radicals chain reactions of alkanes with mechanism in detail. Add a note on
stability of free radicals.
5. Explain the mechanism of free radical addition reaction with suitable example.
6. Saytzeff’s eliminations
bromohexane. (feb/mar11)
3. Discuss side chain halogenation in alkyl benzene. Add a note on Resonance in benzyl
radical
6. Define and give the mechanism of 1,2-addition and 1,4-addition reaction. (jan14)
13. Explain the concept of aromaticity and Huckel’s rule. (Aug/sep 12)
14. What is meant by orientation in aromatic nucleus? Using resonance theory explain the
15. With the help of suitable examples explain the term hyperconjugation. (Aug/sep 11)
17. Explain the concept of aromaticefy and Huckel’s rule with examples. (mar13)
21. Explain the stability and resonance hybride of allyl radical. (feb/mar12)
22. Explain the term Hybridization and Hyperconjugation with examples. (feb/mar11)
1. What are electrophilic aromatic substitution reactions? Explain the effect of substituents
2. Why –NH2 group is activating and ortho para directing while –NO2 group is deactivating
6. Nitration
7. Sulphonation
8. What is electorphillic aromatic substitution reaction? Explain the effect of substituents
11. Discuss Friedel Craft’s alkylations with examples and mechanism. Mention any two of
13. Discuss in electrophillic aromatic substitution in benzene with respect to activating and
14. Classify the substituents in electrophillic aromatic substitution reactions. Discuss the
18. State and explain Friedel Crafts alkylation with its limitations. Write a note on Friedel
Crafts alkylation.
20. What is meant by orientation in aromatic nucleus? Using resonance theory explain the
21.
1. Why carboxylic acid are acidic in nature? Write the effect of electron withdrawing groups
on acidity.
2. Describe acidity of carboxylic acids. Chloro acetic acid is more acidic than acetic acid.
Give reason.
3. Explain ionisation of carboxylic acid and write the structure of carboxylate anion.
5. Compare the acidity among formic acid, acetic acid and trichloroacetic acid.
6. Discuss Conversion of acidity to its various derivatives.(JUN/JUL14)
7. Write a note on effect of substituents on acidity of carboxylic acids.
8. Discuss the structure of carboxylate ion and acid acidity of carboxylic acids. (feb/mar12)
9. Write the preparation of various acid derivatives with examples. (Jan 14)
10. Write a note on effect of substituents on the acidity of carboxylic acids. (Aug13)
11. Write a note on the acidity of carboxylic acids. (mar13)
12. Explain the acidity of acids. (feb/mar12)
13. Explain esterification reaction with mechanism. (feb/mar12)
14. Explain the acidity of carboxylic acid and add a note on effect of substiuents. (feb/mar11)
4. Esterification . (Sep12)
8. Compare the acidity and acetic acid and chloroacetic acid. (feb/mar12)
10.
MARKS
1. Discuss the mechanism involved in Perkin condensation
3. Name the products of the reaction of methyl magnesium bromide with formaldehyde and
acetaldehyde.
5. Discuss the nucleophilic addition reaction and write a note on reactivity of aldehydes &
9. Explain Aldol and crossed Aldol condensation atoms with the mechanism. (Sep12)
13. Explain benzoin condensation giving its mechanism and applications. (feb/mar12)
16. Discuss the mechanism involved in Aldol and crossed Aldol condensation. (Jan 14)
18. Explain the mechanism of Cannizzaro and crossed Cannizzaro reaction with appropriate
examples. (feb/mar12)
MARKS
1. Name the products of the reaction of ethyl magnesium bromide with propanaldehyde and
acetaldehyde.
2. Reformatsky reaction.
3. Grignard reagents
7. What is the action of Grignard’s reagent on acetone? Give the reaction. (feb/mar12)
1. Discuss the effect of substituents on acidity of carboxylic acids. Write a note on how
Beckmann Rearrangement
5. Compare the acidity among formic acid, acetic acid and trichloroacetic acid.
11. What are primary and secondary amines? Give examples. (mar13)
(feb/mar12)
MARKS