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    1) Cephalosporins are semi-synthetic antibiotics derived from bacteria or fungi. 2) The statement that cephalosporins have a narrower spectrum of activity than penicillin is true. 3) Cefepime cannot be taken orally.

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    Baby

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    Rahul C Puttu
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    1) Cephalosporins are semi-synthetic antibiotics derived from bacteria or fungi. 2) The statement that cephalosporins have a narrower spectrum of activity than penicillin is true. 3) Cefepime cannot be taken orally.

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    1) Cephalosporins are semi-synthetic antibiotics derived from bacteria or fungi. 2) The statement that cephalosporins have a narrower spectrum of activity than penicillin is true. 3) Cefepime cannot be taken orally.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    43 views3 pages

    Baby

    Uploaded by

    Rahul C Puttu
    1) Cephalosporins are semi-synthetic antibiotics derived from bacteria or fungi. 2) The statement that cephalosporins have a narrower spectrum of activity than penicillin is true. 3) Cefepime cannot be taken orally.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 3

    1) Cephalosporin’s are semi synthetic antibiotics derived from

    a) Cephalosporin – A, bacteria.
    b) Cephalosporin –C, bacteria.
    c) Cephalosporin – C, fungi.
    d) Cephalosporin –A , fungi

    2) Which among the following statement is false regarding cephalosporin antibiotics


    a) They are having Beta - lactom ring
    b) They act by inhibition of cell wall synthesis
    c) They have narrow spectrum of activity tan penicillin
    d) They are obtained from cephalosporin

    3) Which among the following cephalosporin’s cannot be taken by oral route


    a) Cefprozil
    b) Cefdinir
    c) Cefnim
    d) Cefepime

    4) The fallowing system (cefalexin) is a first generation cephalosporin

    Which of the fallowing statement is true for the methyl solutitution at C-3 ?
    a) It is a good leaving group
    b) It is generally good for activity
    c) It is good for oral activity
    d) It act as steric shield
    5) Which of the following statements about cephalosporin is false
    a) They have short half live
    b) They are ineffective against wisteria
    c) They have a B lector ring
    d) None of the above

    6) Later generation of cephalosporin’s have greater gram negative activity than curlier
    generation of cephalosporin

    A) True B) false

    7) Cephalosporin can lie biosynthesized by

    a) val and gly amino acid


    b) cys and glu amino acid
    c) val and cys amino acid
    d) gly and gly amino acid

    8) Cephalosporin act by
    a) Inhibition the multiplication of DNA
    b) Inhibition the bacteria cell wall synthesis
    c) Pausing the cell chemical activity
    d) None of the above

    9) Replacement of ace tony group at C-3 position with which compounds result in oral
    active cephalosporin
    a) CH3, CHO, N b) -COOH, C6 H6, cl
    c) –CH3, cl d) – CH3, - C6 H6

    10) Substitution on aromatic ring (7-acylamino) result.


    a) Decreased gram +ve activity
    b) Decreased lipophilicity
    c) Increased lipophilicity and increased gram +ve activity
    d) Decreased lipophilicity and increased gram +ve activity
    11) Substitution at C3 – position influence
    a) Pharmacydynamic
    b) Pharmacy Rehetic action
    c) None of the above
    d) Both of the above

    12) Which of the fallowing statement is false regarding C3- substitution.


    a) Amide and esters have a border spectrum of activity
    b) Pyridine and imidazole replace acetoxy group show improved activity against P.
    aeruginosa c) Replacement of acetoxy group at C-3 position with NH3, CHO has result in
    orally active compound
    d) None of the above

    13) Which class of cephalosporin’s cannot be taken orally


    a) 4th generation b)5th generation
    c)2nd generation d)both a & b

    14) Which of the following statement about cephalosporin’s is false


    a) Commonly cause skin rashes
    b) Cross reactive with penicilitis
    c) May cause clostridium difficult related colitis
    d) None of the above

    15) Cephalosporin are more stalest towards acid & Beta - lactomases because
    a) Lower strain with the molecules
    b) Tricycle ring system
    c) Higher strain within the molecules
    d) None of the above

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