DETAILED PROJECT REPORT

(DPR)

for

PROPOSED MANUFACTURING OF BULK DRUGS AND

BULK DRUG INTERMEDIATES

of

M/S. SHREE GANESH PHARMA

Plot No. 971/2, GIDC, Jhagadia,
Dist.: Bharuch, Gujarat – 393110
1.0 EXECUTIVE SUMMARY

1.1 Project Details

M/s. Shree Ganesh Pharma proposes manufacturing of bulk drugs and bulk drug
intermediates unit located at Plot No. 971/2, GIDC, Jhagadia, Dist.: Bharuch, Gujarat.

1.2 Products along with Production Capacity

Sr. Product CAS No. Production Capacity

No (MT/Month)
1 Basic Chromium Sulphate 39380-78-4 1000
2 1,3 Dichloro Acetone 534-07-6 50
3 4-AMINO 1,2,4-TRIAZOLE 584-13-4 50
2-Amino-3,5- Dibromo Benzaldehyde
4 50910-55-9 50
(ADBA)
5 1-H 1,2,4 Triazole 288-88-0 200
6 1-H 1,2,4 Triazole Salt (Na Salt) 41253-21-8
7 1-H 1,2,4 Triazole Salt (K Salt) 41253-23-0
8 3-Amino 1,2,4-Triazole 61-82-5 50
2[4-(4-Chlorobutanoyl) Phenyl]-
9 N,N,2-Trimethyl Proponamide (FEXO- -- 50
3)
1-[4(Cyclopropylcarbonyl) Phenyl]1-
10 Methylproponic Acid Cyclchexylamine 1690344-90-1 25
Salt (FEXO-6)
11 Meloxicam 71125-38-7 2
12 Piroxicam 36322-90-4 2
13 Mefenamic Acid 61-68-7 10
14 Fluconazole 86386-73-4 3
15 Ambroxol Hydrochloride 23828-92-4 10
16 Mono Bromo Acetic Acid 79-08-3 200
17 Hydrobromic Acid 48% 10035-10-6 250
1-(2,4-Difluorophenyl)-2-(1H-1,2,4-
18 86404-63-9 30
Triazole-1-yl)Ethanone (DFTA)
1[-2-(2,4-Difluorophenyl)-2,3-Epoxy
19 Propyl]-1H 1,2,4-Triazole Methane 86386-77-8 25
Sulfonate (DFTA EPOXY MESYLATE)
20 AP 200 Acetate 53880-51-6 8
21 Poly Aluminum Chloride 7446-70-0 1000
22 R & D Product -- 1
Total 3016
1.3 Raw Material Requirement

Sr. Consumption
Name of Products Raw Materials
no. (MT/Month)
1 Basic Chromium Chromium Sulphate 160.0
Sulphate Sodium sulphate 60.0
Sugar 70.0
Sulphuric Acid 470.0
Sodium Dichromate 420.0
Sodium Hydroxide 30.0
2 1,3 Dichloro Acetone 1,3 Dichloro-2-Propanol 55.0
Sodium Dichromate 37.0
Sulphuric Acid 55.50
Acetone / Toluene 200.0
3 4-AMINO 1,2,4- Formic Acid 55.0
TRIAZOLE Hydrazine Hydrate 60.0
Methanol (Fresh) 3.0
4 2-Amino-3,5- Dibromo Methyl Anthranilate 27.0
Benzaldehyde (ADBA) Liquid Bromine 28.5
Hydrogen Peroxide 6.0
Methanol (Fresh) 14.0
Tetrahydrofuran (Fresh 0.5
Sodium Borohydride 7.0
Hydrochloric Acid 18.5
Ethylene Dichloride /
1.0
Toluene (Fresh)
Manganese Dioxide 15.5
5 1-H 1,2,4 Triazole Formic Acid 400.0
Ammonia 147.83
Hydrazine Hydrate 92.75
6 1-H 1,2,4 Triazole Salt 1H-1,2,4,Triazole
151.65
(Na Salt) (Dried)
Sodium Hydroxide lye 87.91
7 1-H 1,2,4 Triazole Salt 1H-1,2,4,Triazole
129.0
(K Salt) (Dried)
Potassium Hydroxide lye 104.67
8 3-Amino 1,2,4-Triazole Aminogunidine
50.0
Bichronate
Formic Acid 27.5
9 2[4-(4- Benzene 13.0
Chlorobutanoyl)Phenyl]- Methacrylic Acid 14.5
N,N,2-Trimethyl Aluminum Chloride 45.0
Proponamide (FEXO-3) Sodium Hydroxide 7.0
Thionyl Chloride 20.0
Dimethyl Amine 7.5
 Methylene Dichloride
0.5
(Fresh)
4-Chloro Butyryril
24.0
Chloride
10 1- 2[4-(4-
[4(Cyclopropylcarbonyl) Chlorobutanoyl)Phenyl]-
22.25
Phenyl]1- N,N,2-Trimethyl
Methylproponic Acid Proponamide (FEXO-3)
Cyclchexylamine Salt Hydrochloric Acid 2.75
(FEXO-6) Sodium Hydroxide 6.0
Cyclohexylamine 7.5
Toluene 0.25
Methanol (Fresh) 0.25
11 Meloxicam Saccharin Sodium 1.17
Iso Propyl Chloro
0.78
Acetate
Di Methylformamide
0.06
(Fresh)
Sodium Metal 0.13
Dimethyl Sulphate 0.72
2-Amino-5-Methyl
0.65
Thiozole
O-Xylene (Fresh) 0.11
Ethylene Chloride
0.14
(Fresh)
12 Piroxicam Saccharin Sodium 1.24
Iso Propyl Chloro
0.83
Acetate
Di Methylformamide
0.06
(Fresh)
Sodium Metal 0.14
Dimethyl Sulphate 0.76
2-Amino Pyridine 0.57
O-Xylene (Fresh) 0.12
Chloroform (Fresh) 0.02
Methanol (Fresh) 0.02
Toluene 0.02
13 Mefenamic Acid 2-Chloro Benzoic Acid 12.99
Potassium Carbonate 5.73
Toluene (Fresh) 2.07
Cuprous Chloride 0.83
2,3-Dimethylaniline 5.02
Hydrochloric Acid 1.54
Dimethyl formamide
1.0
(Fresh)
14 Fluconazole 1-{2-2,4-
Diflurophenyl)Oxiran-2-
2.32
yl]methyl}-1H 1,2,4-
Triazole (DFTA Epoxy)
1H-1,2,4,Triazole 0.68
Dimethylformamide
0.05
(Fresh)
15 Ambroxol Hydrochloride Ambroxol Base 9.1
Hydrochloric Acid 0.9
Acetone / IPA (Fresh) 0.1
16 Mono Bromo Acetic Acid Liquid Bromine 240.0
Acetic Acid 90.0
17 1-(2,4-Difluorophenyl)- 1,3 Difluorobenzene 15.3
2-(1H-1,2,4-Triazole-1- Chloro Acetyl Chloride 15.3
yl)Ethanone (DFTA) Aluminium Chloride 18.0
Methylene Dichloride
0.12
(Fresh)
4-Amino 1,2,4-Triazole 11.4
Acetonitriale (Fresh) 0.27
Sodium Nitrite 4.5
18 1[-2-(2,4- DFTA 16.75
Difluorophenyl)-2,3- Cetrimide 27.25
Epoxy Propyl]-1H 1,2,4- Potassium Hydroxide 4.25
Triazole Methane Methylene Dichloride
0.08
Sulfonate (DFTA EPOXY (Fresh)
MESYLATE) Methane Sulfonic Acid 7.25
Acetone (Fresh) 0.25
Potassium Iodide 12.5
Methanol 2.5
Sulphuric Acid 7.25
19 AP-200 Acetate Tetrahydrofuran (Fresh) 2.1
Magnesium Metal 2.1
Methyl Chloride 2.2
6-Chlorohexanol 6.1
2,4-Hexadienyl Acetate 6.3
Toluene (Fresh) 1.6
Hydrochloric Acid 3.3
Lithium Chloride 0.01
Copper Chloride 0.02
Acetic Anhydride 4.6
Sodium Hydroxide 5.4
1.4 Water Requirement and Waste Water Generation, Treatment & Mode of
Disposal
WATER CONSUMPTION:
DESCRIPTION WATER CONSUMPTION
(KL/Day)
Industrial Process 18.5
Boiler 12.0
Cooling 40.0
Washing 5.0
Other 7.7
(scrubbing)
Total 83.2
Domestic 8.0
Gardening 3.5
Grand Total 94.7

WASTE WATER GENERATION:

DESCRIPTION WASTE WATER
GENERATION (KL/Day)
Industrial Process 17.6
Boiler 2.0
Cooling 3.0
Washing 5.0
Other 7.7
(scrubbing)
Total 35.3
Domestic 6.0
Gardening --
Grand Total 41.3

Mode of waste water treatment and treated waste water disposal:

1. High COD & TDS (5.0 KL/Day) industrial waste water will be evaporated in MEE and
MEE condensate will be sent to ETP for further treatment.
2. Low COD (26.7 KL/Day) industrial waste water will be sent to ETP consists of
primary, secondary and tertiary treatment facility to treat the effluent and treated
effluent shall be discharged into deep sea through M/s. NCTL Pipeline, Jhagadia.
3. Scrubbing solution will be sold to authorized end user registered under Rule -9.

1.5 Source of Emission and Air Pollution Source Control Measures (APCM)

SOURCE OF FLUE GAS EMISSION AND APCM:

Sr. Stack attached Stack APCM Pollutant Permissible
No. to Height Limit
(meter)
1 Hot Air Generator 18 Dust Collector SPM 150 mg/Nm3
2 Boiler 18* -- SOx 100 ppm
Cap-3 TPH NOx 50 ppm
 3 Boiler
Cap-1 TPH
(stand by)
4 Multi Fuel Boiler Multi Cyclone +
Cap-2 TPH 24 Bag filter+ Water
Scrubber
5 Thermic Fluid --
Heater 18
Cap:3 Lac Kcal/hr)
6 D.G Set (200 KVA) 9 --
7 D.G Set (750 KVA) --
9
(stand by)

SOURCE OF PROCESS GAS EMISSION AND APCM:

Sr. Vent Attached Vent APCM Pollutant Permissible
No. To Height Limit
(meter)
1 Spray Dryer Ventury PM 150 mg/Nm3
12
(1000 kg/hr) Scrubber
2 Process Emission
Vessel-1
( Mono Bromo Acetic
Acid,
Acetophenone,1-
(2,4- 11 Water Scrubber HCl 20 mg/Nm3
Difluorophenyl)-2-
(1H-1,2,4-Triazol-1-
yl) Ethanone
(DFTA), Mefenamic
Acid)
3 Process Emission
Vessel-2
(1-[4-
(chloromethyl)-1,3- HCl 20 mg/Nm3
Water + Caustic
thiazol-2-yl]-N,N- 11 SO2 40 mg/Nm3
Scrubber
dimethyl Cl2 9 mg/Nm3
lmethanamine.2HCl
(NI-4),(FEXO-
3),(AP-200 Acetate)

1.6 Hazardous Waste Generation and Mode of Disposal

Sr. Hazardous Category Quantity Mode of Disposal
No. Waste (MT/Year)
1 Discarded 33.1 62 MT (Bags & Collection, Storage,
Containers/ Liners) Transportation and disposal
Barrels/liners by selling to registered
366 MT
recycler.
(Drums)
2 Used Oil/Spent Oil 5.1 0.096 Collection, Storage, Sale to
registered recycle/reuse for
 machine lubricants.

3 Process Residue 28.1 15 Collection, Storage,

Transportation and sent to
co-processing or to CHWIF
of M/s. BEIL, Ankleshwar.
4 ETP sludge 35.3 80 Collection, Storage,
Transportation and sent to
common TSDF site of M/s.
BEIL, Ankleshwar.
5 MEE Salt 35.3 216 Collection, Storage,
Transportation and sent to
common TSDF site of M/s.
BEIL, Ankleshwar.
6 Off specification 28.4 36 Collection, Storage,
product Transportation and sent to
co-processing or to CHWIF
of M/s. BEIL, Ankleshwar.
7 Spent Solvent 28.6 2000 Collection, Storage,
Transportation and distill in-
house and reuse plant
premises.
8 Solvent Residue 28.1 144 Collection, Storage,
Transportation and sent to
co-processing or to CHWIF
of M/s. BEIL, Ankleshwar.
9 Distillation Residue 20.3 120 Collection, Storage,
Transportation and sent to
co-processing or to CHWIF
of M/s. BEIL, Ankleshwar.
10 Manganese Oxide 28.1 153 Collection, Storage,
Transportation and sell to
end user under rule-9.
11 Aluminum Chloride B-10 2302 Collection, Storage,
Transportation and sell to
end user under rule-9.
12 Potassium Iodide 28.1 1020 Collection, Storage,
solution Transportation and sell to
end user under rule-9.
13 Sodium Bisulfite -- 880 Collection, Storage,
(28-32%) Transportation and sell to
end user under rule-9.
14 Dil. HCl (30%) 26.3 1400 Collection, Storage,
Transportation and sell to
end user under rule-9.
 15 Spent Catalyst 28.2 12 Collection, Storage,
Transportation and send to
regenerator

1.7 Green Belt

Total 11,136 m2 land area is available at site; out of this 3,340 m2 (i.e. 30% of total area)
will be developed as greenbelt and other forms of greenery.

1.8 Power & Fuel Requirements

Power Source: DGVCL = 450 KVA
D.G Set = 100 KVA x 2 Nos. (stand by)

Fuel Requirement:
Sr. Fuel Consumption
No.
1 Natural Gas 400 Nm3/hr
2 Coal OR 300 Kg/Hr OR 600 Kg/Hr
Briquette
3 Diesel 190 Lit/Hr

1.9 Salient Features of Project

Sr. No. Salient Features Details
1 Project name and location M/S. Shree Ganesh Pharma
Plot No. 971/2, GIDC, Jhagadia,
Dist.: Bharuch, Gujarat – 393110
2 Status of Land acquisition Open plot
3 Land area of project site 11136 m2
4 Total Cost of the Project: 6.0 Crore
Rs. (Crore)
5 Fuel to be used • Natural Gas- 400 Nm3/hr
• Coal OR Briquette- 300 Kg/Hr OR 600 Kg/Hr
• Diesel- 190 Lit/Hr
6 Source of Water GIDC water supply
7 Total Water Consumption 94.7 KL/Day
8 Quantity of industrial effluent Domestic : 6.0 KL/Day
generation and domestic Industrial : 35.3 KL/Day
wastewater generation Total : 41.3 KL/Day
9 Treatment of effluent and 1. High COD & TDS (5.0 KL/Day) industrial waste
Mode of Disposal water will be evaporated in MEE and MEE
condensate will be sent to ETP for further
treatment.
2. Low COD (26.7 KL/Day) industrial waste water
will be sent to ETP consists of primary, secondary
and tertiary treatment facility to treat the effluent
and treated effluent shall be discharged into deep
sea through M/s. NCTL Pipeline, Jhagadia.
3. Scrubbing solution will be sold to authorized end
 user registered under Rule -9.
10 Details of air emissions and Sources
APCM • Hot Air Generator
• Boilers
• Multi Fuel Boiler
• Thermic Fluid Heater
• D.G Sets
• Spray Dryer
• Process Emission Vessels
APCM
• Dust Collector
• Multi Cyclone + Bag filter+ Water Scrubber
• Ventury Scrubber
• Water Scrubber
• Water + Caustic Scrubber
11 Hazardous waste generation • Discarded Containers/ Barrels/liners - disposal by
and Disposal mode. selling to registered recycler.
• Used Oil/Spent Oil - Collection, Storage, sale to
registered recycle/reuse for machine lubricants.
• Process Residue- sent to co-processing or to
CHWIF of M/s. BEIL, Ankleshwar.
• ETP sludge- sent to common TSDF site of M/s.
BEIL, Ankleshwar.
• MEE Salt- sent to common TSDF site of M/s.
BEIL, Ankleshwar.
• Off specification product- sent to co-processing or
to CHWIF of M/s. BEIL, Ankleshwar.
• Spent Solvent - distill in-house and reuse plant
premises.
• Solvent Residue- sent to co-processing or to
CHWIF of M/s. BEIL, Ankleshwar.
• Distillation Residue- sent to co-processing or to
CHWIF of M/s. BEIL, Ankleshwar
• Manganese Oxide - sell to end user under rule-9.
• Aluminum Chloride- sell to end user under rule-9.
• Potassium Iodide solution - sell to end user under
rule-9.
• Sodium Bisulfite (28-32%) - sell to end user
under rule-9.
• Dil. HCl (30%) - sell to end user under rule-9.
• Spent Catalyst - send to regenerator
12 Power requirement and Source Power Source: DGVCL = 450 KVA
D.G Set = 100 KVA x 2 Nos. (stand by)

2.0 INTRODUCTION OF THE PROJECT/BACKGROUND INFORMATION

2.1 Identification of the project and project proponent. In case of mining project,
a copy of mining lease/letter of intent should be given.

Identification of the project

Proposes manufacturing of bulk drugs and bulk drug intermediates

Identification of the project partners

Sr. Name Designation Correspondence Address With
No. Contacts
1 Mr. Kiranbhai Zaverbhai Modi Partner Plot No-2509-10-11, Opp. Asian
Paints Gate No-3, GIDC,
Ankleshwar-393002.
Mob:+91 9825046933
E mail: [email protected]
[email protected]
2 Mrs. Sangitaben Partner Plot No-2509-10-11, Opp. Asian
Dineshchandra Modi Paints Gate No-3, GIDC,
Ankleshwar-393002.
Mob:+91 9825155565
3 Mrs. Ashitaben Kiranbhai Modi Partner Plot No-2509-10-11, Opp. Asian
Paints Gate No-3, GIDC,
Ankleshwar-393002.
Mob: +91 9879546933

2.2 Brief description of nature of the Project

Proposes manufacturing of bulk drugs and bulk drug intermediates

2.3 Need for the project and its importance to the country and or region
The demand for products intended to be manufacture is increasing in the country. By
setting up this unit, M/s. Shree Ganesh Pharma will be able to meet the demand of various
products internationally and locally. This will also generate direct and indirect employment
opportunity for various levels of people.

2.4 Demands-Supply Gap

Based on our informal survey of the market with our current customers and various traders,
we have found that there is a big potential for the products we are planning. These products
will be an addition to the current range of group's products.

2.5 Imports vs. Indigenous production

Based on the current cost of indigenous raw materials, it will make us very competitive
against imported finished products and we will be able to export of our finished products.

2.6 Export possibility

We shall explore the possibility of export the products.

2.7 Domestic/Export Markets

Majority of the products will be sold in local market. We shall explore the possibility of
export the products.

2.8 Employment Generation (Direct and Indirect) due to project.

M/s. Shree Ganesh Pharma will give direct employment to local people based on
qualification and requirement. In addition to direct employment, indirect employment shall
generate ancillary business to some extent for the local population.

3.0 Project Description

3.1Type of Project including interlinked and interdependent projects, if any.
No interlinked project has been submitted.

3.2 Location (map showing general location, specific location and project
boundary & project site layout) with coordinates.

Map showing general location

Project
Site
Specific location and project boundary
Plant Layout:
3.3 Details of alternate sites considered and the basis of selecting the proposed
site, particularly the environmental considerations gone into should be
highlighted.
Looking to the market demand of the products in local & International markets, it was
decided by M/s. Shree Ganesh Pharma for setting up this unit.

Major factors involved in the selection of site are listed below:

• Existing operational facility.
• Site situated in Notified Industrial Estate.
• Site is well connected by road & Rail.
• Proximity to raw material suppliers.
• Availability of power and cleaner fuel - natural gas.
• Availability of water from GIDC water supply.
• Availability of skilled workmen.
• Proximity to cities like Bharuch and Ankleshwar, ensure access to already existing
social and commercial infrastructure.

Modern infrastructure support and amenities at par in other global markets, including:
Efficient transport facilities.
Environment-friendly zone.
Uninterrupted power supply.

3.4 Size or Magnitude of Operation

Refer: Section-1.0, Sub-section 1.2 of this report.

3.5 Project Description with process details (a schematic diagram/flow chart

showing the project layout, components of the project, etc. should be given)
Refer: Annexure 1.

3.6 Raw Material required along with estimated quantity, likely source,
marketing area of final product/s, mode of transport of raw material and
Finished product.
Refer: Section-1.0, Sub-section 1.3 of this report.

3.7 Resource optimization/recycling and reuse envisaged in the project, if any,

should be briefly outlined.
Every effort will be put to recycle/reuse the water.

3.8 Availability of water its source, energy/power requirement and source

should be given.
Water Source: Total water requirement shall be met through GIDC water supply.

Power & Fuel Requirement

Refer: Section-1.0, Sub-section 1.8 of this report.
3.9 Quantity of wastes to be generated (liquid and solid) and scheme for their
management/disposal.
Refer: Section-1.0, Sub-section 1.4 and 1.6 of this report.

4.0 Site Analysis

4.1 Connectivity

• Site situated in Notified Industrial Estate.

• Site is well connected by road & Rail
• Proximity to raw material suppliers
• Availability of power and cleaner fuel - natural gas.
• Availability of water from GIDC water supply
• Availability of common TSDF and common incineration sites in nearby estate.
• Availability of skilled workmen
• Proximity to cities like Bharuch and Ankleshwar, ensure access to already existing
social and commercial infrastructure.

4.7Social infrastructure available.

Depending on the growth of the company the required social infrastructure will be
provided.

5.0 Planning Brief

5.1 Planning Concept (type of industries, facilities, transportation etc) Town

and Country planning/Development authority classification.

Type of Industry: Proposed manufacturing of bulk drugs and bulk drug intermediates.

5.3 Land use planning (breakup along with green belt etc.)
Total 11136 m2 land area is available at site; out of this 3,340 m2 (i.e. 30% of total
area) will be developed as greenbelt and other forms of greenery.

6.0 Infrastructure Details

6.1 Proposed Infrastructure
Proposed unit is in GIDC, Jhagadia.

6.2 Social Infrastructure

Depending on the growth of the company the required social infrastructure will be
provided.

6.3 Connectivity (Traffic and Transportation Road/Rail/Metro/Water ways etc)

Major factors involved in the selection of site are listed below:

• Site situated in Notified Industrial Estate.

• Site is well connected by road & Rail
• Proximity to raw material suppliers
• Availability of power and cleaner fuel - natural gas.
• Availability of water from GIDC water supply
• Availability of skilled workmen
• Proximity to cities like Bharuch and Ankleshwar, ensure access to already existing
social and commercial infrastructure.

6.4 Drinking water Management (Source & Supply of water)

Water requirement shall be met through GIDC water supply.

6.5 Sewerage System

Sewage pipes will be laid in entire company for the removal and disposal of mainly non-
harmful liquid wastes from the offices, canteen and domestic waste coming from
different sections of the industry. These liquid wastes will be sent to septic tank & soak
pit.

6.6 Solid Waste Management

Reference: Section-1.0, Sub-section 1.6 of this report.

6.7 Power Requirement & Supply/Source

Reference: Section-1.0, Sub-section 1.8 of this report.

7.0 Rehabilitation and Resettlement (R & R) Plan

7.1 Policy to be adopted (central/state) in respect of the project affected

including home ousters, land ousters and landless laborers (a brief outline to
be given)
There is no habitation on the proposed project activity area and it is open industrial land
which is purchased from GIDC for development of factory, so R & R policy is not
applicable to this project.
There shall not be displacement of any population in project area. Any major activity
that may lead to resettlement of the people is considered as permanent impact. Hence,
there is no permanent impact on this account. The increasing industrial activity will
boost the commercial and economical status of the locality up to some extent.

8. Project Schedule & Cost Estimates

8.1 Likely date of start of construction and likely date of completion (Time
schedule for the project to be given).
We shall start construction of proposed project after getting CTE and we shall start
production after applying for CCA.
8.2 Estimated Project cost along with analysis in terms of economic viability of
the project.
Total costs of the project will Rs. 6.0 Crore. Capital cost for EMS (Environmental
Management System) will be Rs. 1.2 Crore.

9. Analysis of Proposal (Final Recommendations)

9.1 Financial and social benefits with special emphasis on the benefit to be
local people including tribal population, if any, in the area.
• Employment would be as per prevailing norms of state government for skilled and
unskilled people for the proposed project.
• Social Welfare shall be done.
• Cordial relation with the industry shall be established and representation shall be
made to villagers for help for creation of facilities related to health, education, etc.