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    Pathophysiology of Appendicitis

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    Danesa Mado
    The document outlines the pathophysiological process that occurs during appendicitis. It starts with constipation and a low fiber diet leading to obstruction of the appendix, which decreases blood flow and oxygen supply, causing the appendix to become necrotic and infected. This triggers an inflammatory response and activation of the vomiting center, resulting in symptoms like abdominal pain, nausea, and vomiting.

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    Pathophysiology of Appendicitis

    Uploaded by

    Danesa Mado
    39 views1 page
    The document outlines the pathophysiological process that occurs during appendicitis. It starts with constipation and a low fiber diet leading to obstruction of the appendix, which decreases blood flow and oxygen supply, causing the appendix to become necrotic and infected. This triggers an inflammatory response and activation of the vomiting center, resulting in symptoms like abdominal pain, nausea, and vomiting.

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    20792200 Pathophysiology of Appendicitis

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    The document outlines the pathophysiological process that occurs during appendicitis. It starts with constipation and a low fiber diet leading to obstruction of the appendix, which decreases blood flow and oxygen supply, causing the appendix to become necrotic and infected. This triggers an inflammatory response and activation of the vomiting center, resulting in symptoms like abdominal pain, nausea, and vomiting.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    39 views1 page

    Pathophysiology of Appendicitis

    Uploaded by

    Danesa Mado
    The document outlines the pathophysiological process that occurs during appendicitis. It starts with constipation and a low fiber diet leading to obstruction of the appendix, which decreases blood flow and oxygen supply, causing the appendix to become necrotic and infected. This triggers an inflammatory response and activation of the vomiting center, resulting in symptoms like abdominal pain, nausea, and vomiting.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
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    Episodes of Constipation Low Fiber Diet

    ↓ ↓
    ↓
    Occlusion of Appendix by Fecalith
    ↓
    Decreased flow/drainage of mucosal secetions
    ↓
    Increased ILP in the appendix
    ↓
    Vasocongestion
    ↓
    Decreased blood supply in the appendix
    ↓
    Decreased O2 supply in the appendix
    ↓
    Appendix starts to be necrotic; Bacteria invade the appendix
    ↓
    Disruption of Cell Membrane of Appendix
    ↓
    Start of Inflammatory Process
    ↓
    ↓ ↓ ↓
    Release of Chemical Mediators Activation of the Vomiting Neutrophils to area
    Center in the Medulla
    ↓ ↓
    ---> Histamine, Prostaglandin, Stimulation of Vagus Suppression of Pus Formation
    Leukotrienes, Bradykinin Nerve Sympathetic (phagocytized bacteria
    ↓ GI Function and dead cells)

    Swelling of Appendix Risk for Infection


    (if appendix ruptures)
    ---> Prostaglandin, Bradykinin Nausea & Vomiting Anorexia
    ↓
    Pain in the RLQ of Abdomen Risk for Deficient Risk for Imbalanced Nutrition
    ↓ Fluid Volume less than body requirements
    Acute Pain
    ---> Interleukin-1
    ↓
    Increased WBC

    Inflammation of Appendix (Appendicitis) <


    ↓
    Appendectomy
    ↓
    Tissue Trauma

    ↓
    Open Wound Disruption of Cell Membrane Nociceptors on the
    ↓ ↓ ↓ Dermis
    Impaired Tissue Risk for Start of Inflammatory ↓
    Integrity Infection Process Send Impulse to CNS

    Release of Prostaglandin/ Pain on Surgical


    Bradykinin Site

    Activity Intolerance

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