BIOMOLECULES Ncert Class 12 Most Important Questions
BIOMOLECULES Ncert Class 12 Most Important Questions
BIOMOLECULES Ncert Class 12 Most Important Questions
1. Biomolecules are (a) aldehydes and ketones (b) acids and esters (c) carbohydrates, proteins and fats (d) alcohols
and phenols
2. Which of the following is a disaccharide ? (a) Lactose (b) Starch (c) Cellulose (d) Fructose
3. Which of the following monosaccharide is pentose ? (a) Glucose (b) Fructose (c) Arabinose (d) Galactose
4. The commonest disaccharide has the molecular formula (a) C10H18O9 (b) C10H20O10 (c) C18H22O11 (d) C12H22O11
5. Monosaccharides usually contains ... carbon atoms. (a) C3 to C10 (b) C1 to C6 (c) C4 to C10 (d) C5 to C8
6. Reducing sugars reduce. (a) only Fehling’s solution (b) only Tollen’s solution. (c) both (a) & (b) (d) neither (a) nor
(b)
7. Which among the following is the simplest sugar? (a) Glucose (b) Starch (c) Cellulose (d)None of these
8. Glucose can’t be classified as (a) hexose (b) carbohydrate (c) aldose (d) oligosaccharide
9. Which of the following properties of glucose cannot be explained by its open chain structure? (i) Glucose does not
form hydrogen sulphite with NaHSO3 (ii) On oxidation with HNO3 glucose gives saccharic acid. (iii) Glucose is
found to exist in two different crystalline forms which are named as α and β. (a) (ii) only (b) (i) and (iii) (c) (ii) and
(iii) (d) (i) and (ii)
10. Which of the following gives positive Fehling solution test? (a) Protein (b) Sucrose (c) Glucose (d) Fats
11. Which of the following statements is incorrect regarding glucose? (a) It is an aldohexose. (b) It is also known as
dextrose (c) It is monomer of cellulose. (d) It is the least abundant organic compound on earth.
12. Glucose gives silver mirror test with Tollen’s reagent. It shows the presence of (a) acidic group (b) alcoholic group
(c) ketonic group (d) aldehyde group
13. The symbols D and L represents (a) the optical activity of compounds. (b) the relative configuration of a particular
stereoisomer. (c) the dextrorotatory nature of molecule. (d) the levorotatory nature of molecule
14. The function of glucose is to (a) provides energy (b) promote growth (c) prevent diseases (d) perform all above
15. Which one of the following compounds is different from the rest? (a) Sucrose (b) Maltose (c) Lactose (d) Glucose
16. The two functional groups present in a typical carbohydrate are: (a) – CHO and – COOH (b) > C = O and – OH (c) –
OH and – CHO (d) – OH and – COOH
17. When glucose reacts with bromine water, the main product is (a) gluconic acid (b) glyceraldehyde (c) saccharic acid
(d) acetic acid
18. Glucose does not react with (a) Br2/H2O (b) H2NOH (c) HI (d) NaHSO3
19. Glucose reacts with acetic anhydride to form (a) monoacetate (b) tetra-acetate (c) penta-acetate (d) hexa-acetate
20. Reduction of glucose by HI suggest that (a) presence of OH groups (b) presence of –CHO group (c) cyclic structure
of glucose (d) six carbon atoms are arranged in straight chain
21. Which of the following reactions of glucose can be explained only by its cyclic structure? (a) Glucose forms
pentaacetate (b) Glucose reacts with hydroxylamine to form an oxime (c) Pentaacetate of glucose does not react with
hydroxylamine (d) Glucose is oxidised by nitric acid to gluconic acid
22. Which is the least stable form of glucose ? (a) α-D-Glucose (b) β-D-Glucose (c) Open chain structure (d) All are
equally stable
23. The α -D glucose and β -D glucose differ from each other due to difference in carbon atom with respect to its (a)
conformation (b) configuration (c) number of OH groups (d) size of hemiacetal ring
24. The two forms of D α glucopyranose obtained from the solution of D α glucose are called (a) isomers (b) anomers
(c) epimers (d) enantiomers
25. Choose the correct relationship for glucose and fructose (a) these are functional isomers (b) these are chain isomers
(c) these are position isomers (d) All of these
26. The letter D and L in carbohydrates represent (a) its optical rotation (b) its mutarotation (c) its direct synthesis (d) its
configuration
27. Which of the following statement is correct about fructose? (a) It is dextrorotatory compound (b) It exists in the two
cyclic forms which is obtained by the addition of OH at C-5 to the >C=O group (c) It exists as six membered ring (d)
It is named as furanose as it contain one oxygen and six carbon atom
28. Fructose is (a) a hemiacetal (b) an acetal (c) a hemiketal (d) a ketal
29. The sugar present in fruits is (a) fructose (b)Glucose (c)Sucrose (d) galactose
30. The sugar present in honey is (a) sucrose (b) glucose (c) fructose (d) maltose
31. The sugar present in honey is (a) sucrose (b) glucose (c) fructose (d) maltose
32. Which of the following is the sweetest sugar? (a) Sucrose (b) Glucose (c) Fructose (d) Maltose
33. Cellulose is a polymer of (a) Glucose (b) Fructose (c) Ribose (d) Sucrose
34. Sucrose on hydrolysis gives (a) fructose+ribose (b) glucose + fructose (c) glucose+glucose (d) fructose + fructose
35. Read the following statements and choose the correct answer? (i) All monosaccharides are reducing sugars. (ii) All
monosaccharides are not reducing sugars. (iii) In disaccharides if aldehydic or ketonic groups are bonded, these are
non– reducing sugars. (iv) In disaccharides if aldehydic or ketonic groups are free, these are reducing sugars. (a) (i),
(iii) and (iv) (b) (ii), (iii) and (iv) (c) (i) and (iv) (d) (ii) and (iv)
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36. Which of the following statement(s) is/are correct? (i) Glucose is reducing sugar (ii) Sucrose is reducing sugar (iii)
Maltose is non reducing sugar (iv) Lactose is reducing sugar (a) (i) and (ii) only (b) (i) and (iii) only (c) (i) and (iv)
only (d) All of these
37. Which of the following statements regarding carbohydrates are correct? (i) Lactose is the carbohydrate found in milk.
(ii) More than 25 monosaccharides occur naturally. (iii) Sucrose on hydrolysis gives one molecule each of glucose
and fructose. (iv) Maltose is a non-reducing sugar whereas sucrose is a reducing disaccharide sugar. (a) (i), (ii) and
(iii) (b) (i) and (iii) (c) (ii), (iii) and (iv) (d) (iii) and (iv)
38. Read the following statements. (i) Pyran is a cyclic organic compound with one oxygen atom and five carbon atom.
(ii) The cyclic structure of glucose is correctly represented by Haworth strucure. (iii) Five membered cyclic structure
of glucose is called pyranose structure. Which of the following statement(s) is/are true? (a) (i) and (iii) (b) (i) and (ii)
(c) Only (iii) (d) (i), (ii) and (iii)
39. Consider the following statements. (i) Linkage between two monosaccharide units through oxygen atom is called
glycosidic linkage. (ii) Sucrose on hydrolysis gives an equimolar mixture of fructose and glucose which is
dextrorotatory. (iii) Lactose consists of linkage between C1 of galactose and C4 of glucose. (iv) Out of two
components of starch the component present in greater proportion is insoluble in water. (v) Glycogen is also known as
animal starch because it is structurally similar to amylose a component of starch. Which of the following is the correct
code for statements above? (a) FFFTT (b) FTTTF (c) TFTFT (d) TFTTF
40. Read the following statements. (i) Haworth structure of α–D– glucose will be .
(ii) Fructose belongs to D–series and is a laevorotatory compound.
(iii) Haworth structure for β–D–fructose will be.
A B C
a) A = Fructose, B = Gluconic acid, C = Tartaric acid
b) A = Glucose, B = Saccharic acid, C = Gluconic acid
c) A = Glucose, B = Gluconic acid, C = Saccharic acid
d) A = Fructose, B = Gluconic acid, C = Saccharic acid
48. Identify the reagent ‘X’ in the following reaction.
X
→
a) CH3COOH (b)Conc. HNO3 (c) (CH3CO)2O (d) CH3COOCH3
49. During acetylation of glucose it needs ,x moles of.acetic anhydride. The value of x would be (a) 3 (b) 5 (c) 4 (d) 1
50. On oxidation with a mild oxidising agent like Br2/H20, the glucose is oxidized to (a) saccharic acid(b) glucaric acid(c)
gluconic acid (d) valeric acid
51. Which reagent is used to convert glucose into saccharic acid? (a) Br2/H2O (b) Nitric acid (c) Alkaline solution of
iodine (d) Ammonium hydroxide
52. The α-and β-forms of glucose are (a) isomers of D (+) glucose and L (-) glucose respectively (b) diastereomers of
glucose (c) anomers of glucose (d) isomers which differ in the configuration of C-2
53. Which of the following is a non-reducing sugar? (a) Glucose (b) Sucrose(c) Maltose (d) Lactose
54. Glucose Product is (a) hexanoic acid (b) gluconic acid (c) saccharic acid(d)bromohexane
55. How many C-atoms are there is a pyranose ring (a) 3 (b) 5 (c) 6 (d) 7
56. The letter ‘D’ in carbohydrates signifies (a) dextrorotatory (b) configuration(c) diamagnetic nature (d) mode of
synthesis
57. Among the naturally occurring carbohydrates, furanose ring is found in the (a) Glucose unit of cane sugar (b) Glucose
unit of cellulose (c) Fructose unit of cane sugar (d) Galactose unit of lactose
58. Amino acids are the building blocks of (a) fats (b) proteins (c) vitamins (d) carbohydrates
59. Which one of the amino acids can be synthesised in the body? a) Alanine (b) Lysine (c) Valine (d) Histidine
60. Two functional group that are present in all amino acids are the (a) hydroxy, amine (b) hydroxy, amide (c) carboxyl,
amino (d) carboxyl, amide
61. In aqueous solution, an amino acid exists as (a) cation (b) anion (c) dianion (d) zwitter ion
62. Which one of the following statements is correct? (a) All amino acids except lysine are optically active (b) All amino
acids are optically active (c) All amino acids except glycine are optically active (d) All amino acids except glutamic
acids are optically active
63. Amino acids generally exist in the form of Zwitter ions. This means they contain (a) basic—NH2 group and acidic —
COOH group (b) the basic—NH3+ group and acidic —COO– group (c) basic—NH2 and acidic —H+ group (d)
basic–COO– group and acidic—NH3+group
64. Which of the following molecules is capable of forming Zwitter ion? (a) NH2CH2COOH (b) CH3CH2NH2 (c)
CH3CH2COOH (d) All of these
66. Simplest proteins has one peptide linkage. It is (a) tripeptide (b) dipeptide (c) tetrapeptide (d) oligopeptide
67. A nanopeptide contain how many peptide bond (a) 7 (b) 9 (c) 8 (d) 10
68. Proteins are polypeptide of (a) α-amino acid (b) α -hydroxy acid (c) D- α -amino acid (d) L- α -amino acid
69. Globular proteins are present in (a) blood (b) eggs (c) milk (d) all of these
70. In fibrous proteins, polypeptide chains are held together by (a) van der waals forces (b) electrostatic forces of
attraction (c) hydrogen bonds (d) covalent bonds
71. Which of the following is not a function of proteins? (a) Formation of hair, wool, skin and nails (b) As a biological
catalysts in the form of enzymes. (c) As food in the form of meat, eggs (d) As energy provider for metabolism
72. Which of the following is not a fibrous protein? (a) Keratin (b) Myosin (c) Insulin (d) Both (a) and (b)
73. A polypeptide with more than hundred amino acid residues, having molecular mass higher than 10,000 u is called .
(a) nucleic acid (b) hormone (c) protein (d) enzyme
74. Which of the following is not a characteristics of fibrous proteins? (a) In the fibrous proteins polypeptide chains are
held together by hydrogen and disulphide bonds. (b) These have fibre like structure. (c) These are generally soluble
in water. (d) These have elongated shape.
75. Which of the following statements is true about a peptide bond (RCONHR)? (a) It is non planar. (b) It is capable of
forming a hydrogen bond. (c) The cis configuration is favoured over the trans configuration. (d) Single bond
rotation is permitted between nitrogen and the carbonyl group.
76. Proteins are condensation polymers of (a) α-amino acids (b) β-amino acids (c) α-hydroxy acids (d) β-hydroxy acids
77. Primary structure of a protein is (a) sequence in which -amino acid are linked to one another (b) sequence in which
amino acids of one polypeptide chain are joined to other chain (c) the folding patterns of polypeptide chains (d) the
pattern in which the polypeptide chain are arranged
78. The protein that transport oxygen in the blood stream is (a) haemoglobin (b) insulin (c) collagen (d) albumin
79. The helical structure of protein is stabilized by (a) dipeptide bonds (b) hydrogen bonds (c) ether bonds (d) peptide
bonds
80. Which of the following statements is incorrect? (a) In α-helix structure a polypeptide chain forms all possible
hydrogen bonds by twisting into a right handed screw. (b) In β-structure of proteins all peptide chains are stretched
out to nearly maximum extension. (c) During denaturation 1° and 2° structures are destroyed but 3° structure remains
intact. (d) All the above statements are incorrect.
81. Which of the following indicates the order in which amino acids are linked together in a protein ? (a) Primary
structure (b) Secondary structure (c) Tertiary structure (d) Quaternary structure
82. Which of the following statement is not true about secondary structure of protein ? (a) The alpha helix, beta pleated
sheet and beta turns are examples of secondary structure of protein. (b) The ability of peptide bonds to form
intramolecular hydrogen bonds is important to secondary structure. (c) The steric influence of amino acid residues is
important to secondary structure. ( d) The hydrophilic/ hydrophobic character of amino acid residues is important to
secondary structure
83. Which of the following terms indicates to the arrangement of different protein subunits in a multiprotein complex ?
(a) primary structure (b) secondary structure (c) tertiary structure (d) quaternary structure
84. Secondary structure of protein is mainly governed by (a) hydrogen bonds (b) covalent bonds (c) ionic bonds (d)
disulphide bonds
85. The secondary structure of a protein refers to (a) fixed configuration of the polypeptide backbone (b) α- helical
backbone (c) hydrophobic interactions (d) sequence of α- amino acids
86. Tertiary structure of protein arises due to (a) folding of polypeptide chain (b) folding, coiling and bonding of
polypeptide chain (c) linear sequence of amino acid in polypeptide chain (d) denatured proteins
87. Denaturation of proteins leads to loss of its biological activity by (a) Formation of amino acids (b) Loss of primary
structure (c) Loss of both primary and secondary structures (d) Loss of both secondary and tertiary structures
88. Coagulation of protein is known as (a) dehydration (b) decay (c) deamination (d) denaturing
89. Which of the following terms refers to the overall three dimensional shape of a protein. (a) Primary structure (b)
Secondary structure (c) Tertiary structure (d) Quaternary structure
90. Which of the following indicates to ‘regions of ordered structure within a protein’. (a) Primary structure (b)
Secondary structure (c) Tertiary structure (d) Quaternary structure
91. The couplings between base units of DNA is through : (a) Hydrogen bonding (b) Electrostatic bonding (c) Covalent
bonding (d) van der Waals forces
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92. Which of the following is correct about H-bonding in nucleotide? (a) A --- A and T --- T (b) G --- T and A --- C (c)
A --- G and T --- C (d) A --- T and G --- C
93.
94. In DNA, the complimentary bases are: (a) Adenine and thymine; guanine and cytosine (b) Adenine and thymine ;
guanine and uracil (c) Adenine and guanine; thymine and cytosine (d) Uracil and adenine; cytosine and guanine
95. In DNA the linkages between different nitrogenous bases are : (a) peptide linkage (b) phosphate linkage (c) H-
bonding (d) glycosidic linkage
96. DNA multiplication is called as (a) translation (b) transduction (c) transcription (d) replication
97. Chromosomes are made from (a) proteins (b) nucleic acids (c) proteins and nucleic acids (d) carbohydrates and
nucleic acids
98. The double helical structure of DNA was proposed by (a) Watson and Crick (b) Meichers (c) Emil Fischer (d)
Khorana
99. α - Helix is found in (a) DNA (b) RNA (c) lipid (d) carbohydrates
100. Which of the following compounds is responsible for the transmission of heredity characters? (a) RNA (b) DNA
(c) Glucose (d) Haemoglobin
101. Energy is stored in our body in the form of (a) ATP (b) ADP (c) fats (d) carbohydrates
102. The chemical change in DNA molecule that could lead to synthesis of protein with an altered amino acid
sequence is called (a) replication (b) lipid formation (c) cellular membrane (d) mutation
103. DNA has deoxyribose, a base and the third component which is (a) phosphoric acid (b) ribose (c) adenine (d)
thymine
104. The process by which synthesis of protein takes place based on the genetic information present in m-RNA is
called (a) Translation (b) Transcription (c) Replication (d) Messenger hypothesis
105. When adenine is attached to ribose sugar, it is called adenosine. To make a nucleotide from it, it would require
(a) oxygenation (b) addition of a base (c) addition of phosphate (d) hydrogenation
106. Which of the following is not present in a nucleotide? (a) Guanine (b) Cytosine (c) Adenine (d) Tyrosine
107. The function of DNA in an organism is (a) to assist in the synthesis of RNA molecule (b) to store information of
heredity characteristics (c) to assist in the synthesis of proteins and polypeptides (d) All of these
108. Which of the following statements regarding DNA fingerprinting is incorrect? (a) It is used in forensic
laboratories for identification of criminals. (b) It cannot be altered by surgery. (c) It is different for every cell and
cannot be altered by any known treatment. (d) It is used to determine paternity of an individual.
109. Which among the following statements are true for glycine? (i) It exists in crystalline form (ii) It is optically
active (iii) It is soluble in water (iv) It can form Zwitter ions (a) (i), (ii) and (iii) (b) (i), (ii) and (iv) (c) (i), (iii) and
(iv) (d) (ii), (iii) and (iv)
110. Which of the following statements are correct? (i) Proteins on hydrolysis gives only α-amino acids. (ii) Gln
stands for glutamic acid. (iii) Amino acids with equal number of amino and carboxyl groups are neutral. (iv) All
naturally occuring α-amino acids are optically active. (a) (i) and (iii) (b) (i), (ii) and (iv) (c) (iii) and (iv) (d) (ii), (iii)
and (iv)
111. Which of the statements about "Denaturation" given below are correct ? (i) Denaturation of proteins causes loss
of secondary and tertiary structures of the protein. (ii) Denaturation leads to the conversion of double strand of DNA
into single strand (iii) Denaturation affects primary strucrture which gets distorted (a) (ii) and (iii) (b) (i) and (iii) (c)
(i) and (ii) (d) (i), (ii) and (iii)
112. Which of the following statement(s) is/are correct? (i) Information regarding the sequence of nucleotides in the
chain of a nucleic acid is called its primary structure. (ii) In secondary structure of DNA adenine forms hydrogen
bonds with guanine whereas cytosine forms hydrogen bonds with thymine. (iii) RNA molecules are of three types m-
RNA, r-RNA and t-RNA and they all perform different functions. (a) (ii) only (b) (i) and (iii) (c) (ii) and (iii) (d) (iii)
only
113. Consider the following statements. (i) Nucleic acids are long chain polymers of nucleotides. (ii) Sugar moiety in
DNA molecules is β-D-ribose whereas in RNA molecules it is β-D-2-deoxyribose. (iii) RNA contains four bases viz.
adenine (A), guanine (G), cytosine (C) and uracil (U) (iv) Nucleotide is a nucleoside linked to phosphoric acid at 4 –
position of sugar moiety. Which of the following is the correct code for the statements above? (a) TFFT (b) TFTF
(c) FFTT (d) FTFF
114. Proteins are found to have two different types of secondary structures viz. α-helix and β-pleated sheet structure.
α-helix structure of the protein is stabilised by : (a) Peptide bonds (b) van der Waals forces (c) Hydrogen bonds (d)
Dipole-dipole interactions
115. Dinucleotide is obtained by joining two nucleotides together by phosphodiester linkage. Between which carbon
atoms of pentose sugars of nucleotides are Are these linkages present? (a) 5′ and 3′ (b) 1′ and 5′ (c) 5′ and 5′ (d) 3′ and
3′Solution
116. Nucleic acids are the polymers of _________(a) Nucleosides (b) Nucleotides (c) Bases (d) Sugars
117. Which of the following statements is not true about glucose? (a) It is an aldohexose. (b) On heating with HI, it
forms n-hexane. (c) It is present in furanose form. (d) It does not give 2,4-DNP test.
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118. Each polypeptide is a protein has amino acids linked with each other in a specific sequence. This sequence of
amino acids is said to be ____________. (a) primary structure of proteins. (b) secondary structure of proteins. (c) the
tertiary structure of proteins. (d) quaternary structure of proteins.
119. DNA and RNA contain four bases each. Which of the following bases is notpresent in RNA?(a) Adenine(b)
Uracil(c) Thymine (d) Cytosine
120. Which of the following bases is not present in DNA? (a) Adenine (b) Thymine (c) Cytosine (d) Uracil
121. Which of the following reactions of glucose can be explained only by its cyclic structure?(a) Glucose forms
pentaacetate.(b) Glucose reacts with hydroxylamine to form an oxime. (c) Pentaacetate of glucose does not react with
hydroxylamine. (d) Glucose is oxidised by nitric acid to gluconic acid.
122. Carbohydrates are classified on the basis of their behaviour on hydrolysis and also as reducing or non-reducing
sugar. Sucrose is a __________. (a) monosaccharide (b) disaccharide (c) reducing sugar (d) Aldohexose
123. Proteins can be classified into two types on the basis of their molecular shape i.e., fibrous proteins and globular
proteins. Examples of globular proteins are :(a) Insulin (b) Keratin (c) Myosin (d) all the above
124. Which of the following monosaccharides are present as five-membered cyclic structure (furanose structure)? (a)
lactose (b) Glucose (c) Fructose (d) Galactose
125. In fibrous proteins, polypeptide chains are held together by ___________. (a) disulphide linkage(b) hydrogen
bonds(c) Both (a) & (b)(d) None of the above
126. Which of the following are purine bases (a) Guanine (b) Adenine (c) Both (a) & (b) (d) None of the above
127. Assertion (A): Fructose reduces Fehling’s solution. Reason (R): Fructose does not contain any aldehyde group.
128. Assertion (A): Glucose gives a reddish - brown precipitate with Fehling’s solution. Reason (R): Reaction of
glucose with Fehling’s solution gives CuO.
129. Assertion (A): Glucose exists in two different crystalline forms – α and β. Reason (R): Glucose forms a six-
membered ring in which —OH at C-5 is involved in ring formation.
130. Assertion (A): The two cyclic forms of glucose (α- and β- glucose) are called epimers. Reason (R): α- and β-
glucose exists in equilibrium with its open-chain structure.
131. Assertion (A): Acetylation of glucose with acetic anhydride gives stable glucose pentaacetate. Reason (R): The
five –OH groups in glucose molecule are attached to different carbon atoms.
132. Assertion (A): All naturally occurring α amino acids except glycine are optically active. Reason(R): Most
naturally occurring α amino acids have L-configuration
133. Assertion(A):Glycine must be taken through diet Reason(R): It is non-essential amino acid
134. Assertion (A): Coagulation of egg white occurs on boiling. Reason(R): Denaturation of protein is occur when a
native protein is subjected to a physical change or a chemical change.
135. Assertion (A): In Zwitter ionic form, amino acids show the amphoteric behaviour. Reason(R): Amino acids in
Zwitter ionic form react with acid and base both.
136. Assertion (A): Albumin is a globular protein. Reason(R): Polypeptide chain coils around to give a straight chain.
137. Assertion (A): Proteins are made up of α amino acids. Reason (R): During denaturation, secondary and tertiary
structures of proteins are destroyed.
138. Assertion (A): The genetic codes are comma less.Reason (R): There are two types of nitrogenous base
139. Assertion (A): The two strands of DNA are parallel. Reason (R): The phenomenon of mutation is chemical
change in DNA molecule.
140. Assertion (A): RNA molecules are of three types. Reason (R): messenger RNA, Ribosomal RNA and transfer
RNA
141. Assertion (A): Nucleotides are joined together to form polynucleotide. Reason (R): The linkage present between
nucleotides is hydrogen bond.
142. Assertion (A): RNA is double stranded. Reason (R): The base Thymine is absent in RNA
143. Assertion (A) The two strands of DNA are complementary.Reason (R) The base sequence of onestrand can be
predicted by knowing base sequence of other strand.
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