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Spermatogenesis

Spermatogenesis is a cell differentiation process that ensures the


production of fertilizing sperm, which ultimately fuse with an egg to
form a zygote. Normal spermatogenesis relies on Sertoli cells, which
preserve cell junctions while providing nutrients for mitosis and meiosis
of male germ cells.Is called spermatogenesis.

Name : YASH BHAGAT


Class : XII – C
Roll no. : 43
School : Kendriya Vidyalaya VayuSena
Nagar, Nagpur
Abstract
Spermatogenesis is the process in which spermatozoa are
produced from male primordial germ cells by way of
mitosis and meiosis. The initial cells in this pathway are
called Spermatogonia, which yield primary spermatocytes
by mitosis. The primary spermatocytes divides
meiotically into two secondary spermatocytes; each
secondary spermatocytes then completes meiosis as it
divides into two spermatids. These develop into mature
spermatozoa, also known as sperm cells. This two cells,
the secondary spermatocytes, and the two secondary
spermatocytes by their subdivision produce four
spermatozoa.
Spermatogenesis starts at the age of puberty due to
significant increase in the hormone secretion of
gonadotropin realising hormone (GnRH). This is a
hypothalamic hormone. The increased levels of GnRH
then acts at the anterior pituitary gland and stimulates
secretion of two Gonadotropins – Luteinising Hormone
(LH) and Follicale Stimulating Hormone (FSH). LH acts
at the leydig cells and stimulates synthesis and secretion
of androgens. Androgens, in turn stimulates the process
of spermatogenesis. FSH acts on the sertoli cells and
stimulates secretion of some factors which help in the
process of spermatogenesis.

Location
Spermatogenesis takes place within several structures of
the male reproductive system. The initial stages occur
within the testes and progress to the epidymis where the
developing gametes mature and are stored until
ejaculation. The seminiferous tubules of the testes are the
starting point for the process, where stem cells adjacent
to the inner tubules wall divide in a centripetal direction
– beginning at the walls and preceding into the innermost
part, or lumen – to produce immature sperm. Maturation
occurs inn the epidymis.

Direction
For humans entire process of spermatogenesis takes 74
days. Including the transport on ductal system, it takes 3
months. Testes produce 200 to 300 million spermatozoa
daily.

Stages
The entire process of spermatogenesis can be broken up
into several distinct stages, each corresponding to a
particular type of cell in human. In the following table,
ploidy, copy number and chromosome / chromatid counts
are of one cell, generally ( in G1 if applicable ).
The primary spermatocytes is arrested after DNA
synthesis and prior to divison.
Spermatogenesis
During spermatogenesis, the spermatids begin to grow a
tail, and develop a thickened mid – piece, where the
microtubules gather and form an anime. Spermatids DNA
also undergoes packaging, becoming highly condensed,.
The DNA is packaged firstly with specific nuclear basic
proteins, Protamines during spermatids elongation. The
resultant tightly packed chromatin is surrounds the
acrosome. One of the centrioles of the cell elongates to
become the tail of the sperm.
Maturation

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