Internet of Things For In-Home Health Monitoring Systems: Current Advances, Challenges and Future Directions
Internet of Things For In-Home Health Monitoring Systems: Current Advances, Challenges and Future Directions
2, FEBRUARY 2021
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PHILIP et al.: IOT FOR IN-HOME HEALTH MONITORING SYSTEMS 301
• Interventions for clients: clients are individuals who are Such applications will continue to rise due to the development
potential or current users of health services. of the recent communication protocol specifically designed for
• Interventions for healthcare providers: Healthcare IoT devices such as NB-IoT, LoraWan or Sigfox. In addition,
providers are members of the health workforce who the latest development in the IoT communication infrastructure
deliver health services. including 3GPP standard (5G IoT) is well positioned to pro-
• Interventions for a health system or resource managers: vide low-power, low-data-rate, and wide-area coverage cellular
managers are involved in the administration and planning connections to diverse types of IoT devices [8].
of public health systems. There has been an increase in the development of intelligent
• Interventions for data services: This includes functional- medical devices (e.g. blood pressure device, glucose meter,
ity to support steps related to data collection, management temperature sensors, weight scale, etc..) and wearable sensors
and processing. (to measure e.g. ECG, accelerometer, SPo2, Heart rate, etc..),
In most of the above intervention groupings, remote health with features focusing on low power, small size, portability and
monitoring applications are part of the end-to-end intervention easy to wear and use. Wearable sensors have gradually been
system. Remote health monitoring applications links the client developed in the form of accessories (e.g. bands, rings), smart
via sensors and home hub to the healthcare providers and clothing, body attachments and body insertions (e.g. insulin
resource managers via cloud data services. pumps, pacemakers). Alongside this development in wearable
To address limited health and social care resources, National sensors, there have been advancements in the design of smart
Health Services’ (NHS) policies and plans are set to change textiles, smart clothing, or e-textile, that consist of conductive
the services models to keep patients treatment at home and textile material that is attached to or woven together. The
community centers to reduce hospitalization, cost and provide tremendous advancements in low-profile and bioelectronics,
a better quality of life. As an example, NHS UK, sets out five nano technologies and materials have led to the development
changes to the NHS service model to address such needs [6]: of implantable sensors and biomedical devices for remote diag-
• Boost ‘out-of-hospital’ care: to dissolve the historic nosis and monitoring. Many challenges were resolved during
divide between primary and community health services. this development including the size of the sensors, battery
• NHS redesign: to reduce pressure on emergency services life and the development of stretchable and skin-attachable
at hospitals. electronic devices that can continuously and unobtrusively
• Empowering patients and personalized care: patients to monitor individuals’ activity and biomedical signals without
get more control over their health. any restriction to the individual’s daily activities. Wearable
• Digitally-enabled care: to be part of the primary and devices are equipped with wireless transceivers modalities,
outpatient care pathways across the NHS. e.g. Bluetooth, Zigbee, infrared, radio-frequency identification
• Integrated care systems: to focus on population health (RFID), WiFi and near-field communication (NFC) technolo-
and partnerships between local NHS organizations. gies. Such technologies allow the wearables to connect to other
The key enabler of these 5 major practical changes to smart devices (e.g. Smartphone) to enable remote diagnosis
the health service model is the remote health monitoring and monitoring for better quality care [9].
applications. The above mentioned ‘out of hospital’ care,
reducing emergency hospital services, personalized care, C. The Reported Evidence on the Benefits of mHealth
digitally enables care and integrated care systems models Applications in Terms of Quality of Care and
cannot happen without remote health monitoring types of Reduction of Cost
applications. In fact, the fast increasing focus towards pre- In-Home health monitoring applications have evolved over
cision medicine and personalized care is one of the factors the last few decades, addressing many healthcare conditions.
fueling the global mHealth market [5]. They aimed to provide more efficient and effective healthcare
services and contributed to a better quality of life and reduction
B. The Advances in the Underlying Enabling Technologies in in cost. There has been a sharp increase in the number of
Terms of Mobile phone capabilities, wireless communications, mHealth smartphone applications targeting various disease
sensors, wearables and IoT architectures and protocols. remote monitoring and self-management, helping patients bet-
The relatively low cost and proliferation of mHealth applica- ter manage their health conditions and enabling independent
tions, due to the massive penetration of smartphones, is making living. It aims to empower individuals through disease preven-
it a promising investment direction across the globe. In 2017, tion, health promotion and condition self-management [5].
it is estimated that 500 million smartphones new users from Based on [12] an estimated 7.1 million patients were
China and India were connected to the internet globally [5]. remotely connected to health monitoring devices in 2016,
Internet of Things (IoT) is an evolving IT revolution pro- which contributed to a saving of £1bn (over five years) for the
viding a paradigm shift in several areas including Healthcare. NHS by reducing bed blocking and unnecessary appointments.
The term “Internet-of-Things” can be defined as “ an umbrella In addition to the above mentioned benefits of remote health
keyword to cover various aspects related to the extension of the monitoring, it gives patients confidence that their conditions
Internet and the Web into the physical realm, by means of the (e.g. heart rate, blood pressure, SPo2 levels and sleep quality)
widespread deployment of spatially distributed devices with are monitored and alerts could be generated to inform their
embedded identification, sensing and/or actuation capabilities, healthcare professionals in real time [12]. In fact, one study
to enable a whole new class of applications and services" [7]. has shown that home monitoring of patients with congestive
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302 IEEE JOURNAL ON SELECTED AREAS IN COMMUNICATIONS, VOL. 39, NO. 2, FEBRUARY 2021
TABLE I
E XAMPLES OF M H EALTH AND A SSISTED L IVING
S ENSORS AND A PPLICATIONS
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PHILIP et al.: IOT FOR IN-HOME HEALTH MONITORING SYSTEMS 303
Fig. 2. Key technologies for IoT based In-home health monitoring systems. Fig. 3. IoT protocols in terms of range and data rate.
The architecture of IoT based in-home health monitoring that allows communications between sensor(s) and personal
systems typically includes five main key IoT technologies computer devices, e.g. smartphone using short-range commu-
as shown in Fig. 2. Inspired by these five technologies, nications that include e.g. Bluetooth, BLE, WIFI and Zigbee.
the following sub-sections presents the current advances in It depends on the required bandwidth. For instance, for sensor
IoT technologies and services for in-home health monitoring signals with a low bandwidth of 0.5 Hz, such as SPo2 signal,
applications. BLE is sufficient to be used to transmit the data [15]. While
A. mHealth and Assistive Sensors 25 lead ECG signals bandwidth can reach 500Hz would need
WiFi communications modalities as the required bandwidth
These represent invasive and non-invasive sensors used to is high [15]. Fig. 3 presents some of the IoT communications
monitor biomedical signals and living environment changes. protocols in terms of data rate and range [16]. Recent protocols
Biomedical signals depend on the individual’s lifestyle, mental are specifically designed for IoT devices such as NB-IoT,
and medical conditions (e.g. diabetes, COPD, Cancer and LoraWan or Sigfox. They are designed to use low-power wide-
mental disorder). Such medical conditions need the manage- area networks (LPWAN) that enable the connection of a large
ment and control of some parameters, e.g. Glucose level, number of devices at a low bit rate, low energy consumption
blood pressure, temperature, ECG and weight. And hence and low cost. In particular, the IEEE 802.15.6, is a wireless
the need for sensors devices to measure these conditions. body area network (WBAN) standard developed for enhanced
For the living environment, it depends on the assistive living health monitoring, which supports data rates up to 10Mbps,
technologies that individuals need, e.g. personal alarms, sensor 1-2 meters range, low power, and high reliability [17]. The
mats, camera, etc. To enable communications of the measured latest development in the IoT communication infrastructure
signal with the surrounding world, these sensors are attached includes the latest 3GPP standard development of (5G IoT)
to wireless communications modalities including, RFID, NFC, to provide low-power, low-data-rate, and wide-area coverage
Bluetooth and BLE, WiFi and Zigbee. cellular connections to diverse types of IoT devices [8]. This
Table 1 represents a list of sensors and devices related to includes two connection types; direct 3GPP connection via
some chronic disease management, adherence and assisted narrowband IoT (NB-IoT) and indirect non-3GPP connection.
living applications. Most of these sensors and devices are For NB-IoT, it requires merely 180 kHz as the minimum
manufactured with data communications standards to allow bandwidth for both uplink and downlink. To support non-
interoperability and communications with applications. Exam- 3GPP 5G IoT connections, a heterogeneous link combining a
ples of such standards are the ISO/IEEE 11073 Personal low-power wide-area network (LPWAN) and cellular networks
Health Data (PHD) and oneM2M. They both are designed via relay user equipment (UE) appears to be a promising
to allow message communications with devices using appli- option [8].
cation layer protocols including Hyper TextTransfer Protocol
(HTTP), Constrained Application Protocol (CoAP), and Mes- C. Middleware Layer
sage Queuing Telemetry Transport (MQTT). It is a service-oriented software layer that allows the
communications with heterogeneous devices like sensors and
B. Short-Range Communications Networks actuators from one end and the cloud services at the other end.
Short-range communications networks are represented in The central role of the middleware layer is to create an abstrac-
this discussion as Wireless sensor networks (WSN) and Per- tion of underlying sensors. The middleware layer acts as a
sonal Area Networks (PAN): WSN, is a network composed mediator between the cloud and sensor devices by collecting
of a set of sensors to monitor different health conditions the sensed data and uploading them to the cloud platform. The
and/or assistive living parameters. Usually, this is referred to middleware layer is usually developed in a unified way that
as Wireless Body Area Network (WBAN) in the case of wear- allows communications with any type of sensor and runs any
able required to be worn by individuals. PAN, is a network applications with minimum configurations [19]. A middleware
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PHILIP et al.: IOT FOR IN-HOME HEALTH MONITORING SYSTEMS 305
TABLE II These modules handle the medical data provided by the end
I OT C LOUD C OMPUTING I NDUSTRIAL P LATFORMS users. Typically, the cloud computing services are designed
with three main objectives: flexibility, scalability and inter-
operability [14]. Interoperability is facilitated through the
adoption of electronic health record handling standards e.g.
HL7 FHIR to a seamless integration between systems. Scal-
ability and flexibility are facilitated by the fact that new
resources can easily be added to the model without chang-
ing the cloud communication API endpoints. The storage
server saves the patient data, bio-signals and bio-parameters
transferred from the patient hub and medically relevant data
resulted from the patient’s evaluation by medical staff. The
feature extraction module retrieves from the storage the raw
signals originating from the patient hub (e.g. ECG). The
module extracts several higher-level features to be used in
the decision process. The decision support system (DSS) is
designed based on semantic web technologies (e.g. RDF,
OWL) and dynamic rules to enhance the inference process.
Some typical functions provided by the decision support
procedure include raising alarm, sending alerts, is to produce
alarms, warnings and notifications about the status of patients’
health based on the patients’ extracted features.
E. IoT Applications
IoT applications constitute the interface between the user
and the devices. They enable device to device, humans to
device, and human to human interactions.. They should be
D. Cloud Computing able to present data intuitively, identify problems and suggest
solutions. Many research studies systematically reviewed the
Cloud computing is another sub-system of in-home health features of such applications for IoT based in-home health
remote monitoring system. It is an internet-based computing remote monitoring for chronic disease self-management. For
platform that is utilized to provide; data storage to store the example, the authors of [52] systematically reviewed the litera-
collected data from the different IoT devices and sensors, ture and identified the features for mobile diabetes applications
servers to process and analyse the collected data, and intel- while the authors of [33] systematically reviewed the literature
ligent systems that used the analysed data to produce alarms identified the features of COPD self-management applications.
and knowledge to support the decision of e.g. healthcare Both studies were based on identifying the main features of
professional for patient treatment. Recently the concept of IoT user applications. The following are examples of such
fog computing was introduced to provide a mix of local features for chronic disease self-management applications:
and cloud-computing services that act as a highly virtualized • Measurement: This is device to device interaction; it
platform that provides computing, storage, and networking allows communication between the application running
services between end devices and traditional cloud computing on a smartphone and the sensors. In case of diabetes,
data centers [63]. Many IoT cloud computing platforms were measurements of blood glucose level.
introduced that can be used as Infrastructure as a Service • Questionnaires: This is a device to human interaction; it
(IaaS), Platform as a service (PaaS) or Software as a Service allows the collection of subjective status (e.g. mood) of
(SaaS), Table II presents the most common IoT platforms the patients via dialogue or validated questionnaires.
and their key characteristics. The table lists these platforms • Educational: This is a device to human interaction; to
along with their characteristics: connectivity, security, data provide personalized education based on patients’ needs
format support, programming language support and analytics (e.g. nutrition information education).
capabilities [32]. When selecting a cloud computing platform • History: This is a device to human interaction; to provide
other factors are important to be considered like pricing model, details about the collected data over a period of time.
availability, deployment type and hardware required. • Diary and reminder: This is a device to human interac-
Fig. 1 gives an example of cloud computing services tion; to remind patients about the treatment plan schedule.
required for an IoT based in-home remote management. These • Communications: This is human to human electronic
services can be hosted on one of the platforms in Table II communications. E.g. via motivational messaging
platforms, e.g. Amazon Web Services. These cloud services between Healthcare professional and patients.
consist of three main parts, the storage server, the feature • Medication: this is device to human interaction; it pro-
extraction module and the decision support system (DSS). vides e.g. the list of medications, frequency and dosage.
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III. C HALLENGES , R ECOMMENDATIONS AND F UTURE one of these models. It identifies QoS metrics as functional
D IRECTIONS OF I OT BASED I N -H OME H EALTH stability, performance, compatibility/interoperability, usabil-
M ONITORING S YSTEMS ity, reliability, security, maintainability/modularity/scalability
As the IoT technologies are becoming affordable and and portability. The work in [39] mapped these metrics to
increasingly accepted by patients and healthcare workers, IoT systems and identified reliability, performance, functional
innovative applications are blooming and continue to be fueled stability, security, compatibility/Interoperability and maintain-
by venture capitals and research funds from both private ability/scalability as QoS metrics in IoT architectures.
sectors and government. The prospect of IoT for eHealth is Based on this QoS list, this paper considers the following
promising, new functions are being added into products and recommendation and future directions that need addressing in
services with technological advances in sensor abilities in the future development of IoT based in-home health remote
hardware, ubiquitous communication, and analytics supports monitoring:
of cloud/fog/big data computing. eHealth is listed as a pri- A. Performance, Functional Stability and Reliability
ority in the European Digital Agenda in Horizon 2020 [34].
These QoS indicators are end-to-end based, applicable to
A saving of almost 100 billion Euro is possible in healthcare
all the sub-components of the IoT architecture starting from
expenses with the aid of eHealth and mHealth. It is expected
the individual’s home to the healthcare cloud services. For
that the market value of all the wearable devices that measure
the cloud services, it is to ensure that the cloud infrastructure
fitness and wellness worldwide will be over $12 billion USD
can serve the maximum expected number of clients without
by 2022 [35]. Recently a buffet of eHealth applications tapping
dropping requests, and also to identify potential performance
on the power of IoT has emerged, ranging from ambient
bottlenecks on the server-side. This will involve monitoring
assisted living for illness prevention to paramedic emergency
of the memory consumption to detect any problems with
services for rescue.
undesired memory leakage and badly designed caching of
A fully integrated in-home health monitoring system, with
data. For the individual’s home end this involves the per-
optimized workflows at the hospitals, is arriving soon in the
formance, functional stability and reliability of the WBAN
future. Since chronic disease treatment and rehabilitation is
and WPAN networking concerning wireless interference from
not a once-off event, a full array of IoT sensors should be in
the coexistence of different short communications modali-
place to facilitate bodily and environmental monitoring as a
ties (e.g. WiFi, ZigBee or BLE that employ the 2.4 GHz
holistic approach. IoT plays an important role in enabling data
ISM band). In particular, WiFi uses the highest transmission
links from multiple places for virtual consultation in future
power compared to other technologies, operating at the same
TeleHealth. Based on this, a doctor and patients’ consultation
frequency band, resulting in a higher interference. Besides,
can be equipped with not just lab results, but also with the
the use of large packet sizes in WiFi technology affects the
history of data remotely measured while patients at home
surrounding wireless devices’ available bandwidth. Wireless
using some wearables and in-home remote patient monitoring
interference can cause intermittent connectivity or unexpected
applications. Using the available data and aided by decision-
disconnections, delays in connection and data transfer, slow
support systems that also have access to big data for other
network speeds, and poor signal strength. Many research
individuals, the doctor can make a better diagnosis and provide
efforts were conducted to study the cause and effect of the
personalized treatment. Such a disruptive technology could
coexistence issues in WBAN (IEEE 802.15.6), WiFi, BLE
have a transformative impact on global healthcare systems
and IEEE 802.15.4 [64]. Energy Consumption Management
and drastically reduce healthcare costs and improve speed and
is another performance metric that can lead to degradation in
accuracy for diagnoses [36].
performance/reliability and functional stability. For example,
The realization of this ambitious scenario and in general
at the individual home end continuous monitoring scenarios
IoT based remote monitoring in the healthcare sector that
mean wearables need to be active for a long amount of time
requires data sharing and transfer between embedded devices
and these can be hours to days, it depends on the clinical
is complex and gives rise to several challenges and open issues
scenario. This means draining the battery that will need re-
that need to be addressed in the future development of such
charging and hence disconnection for the continuous moni-
systems.
toring process. A low battery charge causes symptoms similar
IoT based in-home health remote monitoring is a network
to that caused by wireless interference. Performance/reliability
of systems, devices and sensors which are connected and
and functional stability are vital QoS indicators. Systems with
share data. It is a platform which allows to manage the data
low performance/reliability and functional stability lead to low
and controls the devices remotely based on requirements.
adoptions and acceptance by end-users of such systems [38].
These requirements for IoT systems are measured by the
Developers, testers, evaluators and device manufacturers need
quality of services (QoS) provision by these systems and
to address and solve such indicators. This could eventually
the satisfaction of the end-users’ requirements. This paper
lead to higher adoption of such systems and a scale-up of
addresses the IoT challenges and open issues by mapping
such services in the healthcare sector that as reported in the
them to the IoT QoS and end-users’ requirements. There
literature can lead to a better quality of life and low cost.
is a range of quality factors that can be used to quantify
QoS and many different Quality Models have been pro- B. Security, Privacy. Ethics and Law
posed to identify the QoS metrics in distributed systems. Addressing security and privacy issues in IoT systems
The ISO/IEC 25010 [37] quality model ISO/IEC (2010) is design and development is vital to develop trust in using IoT
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PHILIP et al.: IOT FOR IN-HOME HEALTH MONITORING SYSTEMS 309
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iso.org/standard/71885.html Sponsored Research Recognition Award in 2015. His research is reported
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