Librium Chlordiazepoxide

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NURS 1566 Clinical Form 3: Clinical Medications Worksheets

(You will need to make additional copies of these forms)

Generic Name Trade Name Classification Dose Route Time/frequency


chlordiazepoxide Librium Benzodiazepines 5 mg PO/NG tube BID PRN
antianxiety agents
Peak Onset Duration Normal dosage range
0.5-4 hr 1-2 hr up to 24 hr 5 mg 2-4 times daily initially

Why is your patient getting this medication For IV meds, compatibility with IV drips and/or
anxiety solutions
n/a

Mechanism of action and indications Nursing Implications (what to focus on)


(Why med ordered) Contraindications/warnings/interactions
Depresses the CNS, probably by potentiating Hypersensitivity, those with pre-existing CNS depression,
GABA, an inhibitory neurotransmitter Long--acting benzodiazepines cause prolonged sedation in
the elderly. Appears on Beers list and is associated with
increased risk of falls (↓ dose required or consider short-
acting benzodiazepine.)
Common side effects
Dizziness, drowsiness

Interactions with other patient drugs, OTC or Lab value alterations caused by medicine
herbal medicines (ask patient specifically) Patients on prolonged therapy should have CBC and liver
antidepressants , antihistamines , and opioid function tests evaluated periodically. May cause an
analgesics --concurrent use results in additive CNS increase in serum bilirubin, AST, and ALT, May alter
depression results of urine 17-ketosteroids and 17-ketogenic steroids.
May cause decreased response on metyrapone tests and
decreased thyroidal uptake of 123I and 131I
Be sure to teach the patient the following about this
medication
Instruct patient to take chlordiazepoxide exactly as
directed. If medication is less effective after a few weeks,
check with health care professional; do not increase dose.
Medication should be tapered at the completion of long-
term therapy. Sudden cessation of medication may lead to
withdrawal (insomnia, irritability, nervousness, tremors),
Instruct patient and family how to reduce falls risk at
home.
Nursing Process- Assessment Assessment Evaluation
(Pre-administration assessment) Why would you hold or not give this Check after giving
Assess patient for anxiety and level of med? Decreased sense of anxiety
sedation (ataxia, dizziness, slurred speech) Pt. shows signs of intolerable side Increased ability to
periodically throughout therapy, Assess effects (excessive sedation) cope
risk of falls and institute fall prevention
strategies.

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