Levothyroxine
Levothyroxine
College of Nursing
Center of Excellence (COE) | Level IV Re-Accredited (AACCUP)
Telephone No.: (032) 254 4837
Email: [email protected]/[email protected]
DRUG STUDY G3P3(3003); PTB BACTERIOLOGICALLY CONFIRMED, NEW CASE REGIONAL-
ONGOING INTENSIVE PHASE TREATMENT, PELVIC ORGAN PULAPLE, STAGE IV; S/P
EL; APPENDECTOMY (1996, SPMC); S/P THYROIDECTOMY (2001, CHH FUENTE);
Date of Admission: January 20, 2023 Diagnosis: _
COVID-19 NEGATIVE LABORATORY CONFIRMED
Name of Drug Classification Mechanism of Action Indication Contraindication Side Effects Nursing Responsibilities
Generic Name:
Levothyoxine
Pharmacologic Pharmacodynamics or ● Hypersensitivity; Before Drug Administration:
Classification: Mechanism of Action: ● Thyroid - Verify doctor’s order
Recent MI; ● CNS: headache,
Thyroid Replacement of or supplementation in
Brand Name: Hyperthyroidism insomnia, irritability. - Verify medication labels esp. dosage
preparations supplementation to hypothyroidism.
Levoxyl Treatment or
● CV: angina pectoris, - Assess apical pulse and BP prior to and
endogenous thyroid arrhythmias, periodically during therapy. Assess for
suppression of
Minimum Dose: hormones. Principal euthyroid goiters. tachycardia. tachyarrhythmias and chest pain
2 mcg effect is increasing Adjunctive ● GI: abdominal cramps, - Monitor thyroid-stimulating hormone
metabolic rate of treatment for diarrhea, vomiting. serum levels in adults 8– 12 wks after
Therapeutic body tissues: ● Derm: sweating. changing from one brand to another.
Maximum Dose: Classification:
thyrotropin-
500 mcg Promote dependent thyroid ● Endo: hyperthyroidism,
Hormones During Drug Administration:
gluconeogenesis, cancer. menstrual irregularities.
Patient’s Dose: increase utilization ● Metab: heat intolerance, - Administer with a full glass of water, on
125 mcg tab weight loss. an empty stomach, 30– 60 min before
and mobilization of
● MS: accelerated bone breakfast, to prevent insomnia.
glycogen stores,
Route:
Stimulate protein maturation in children
PO After Drug Administration:
synthesis, Promote - Record accordingly
Frequency:
cell growth and - Instruct patient to take medication as
differentiation, Aid
in the development directed at the same time each day. Take
of the brain and missed doses as soon as remembered
CNS. unless almost time for next dose. If
Therapeutic Effects: more than 2– 3 doses are missed, notify
health care professional. Do not
Replacement in
OD discontinue without consulting health
hypothyroidism to care professional
restore normal - Advise patient to notify health care
Availability / hormonal balance.
Form: professional if headache, nervousness,
Suppression of diarrhea, excessive sweating, heat
Capsules:
thyroid cancer. intolerance, chest pain, increased pulse
13mcg, 25, 50,
rate, palpitations, weight loss >2 lb/wk,
75, 88, 100,
or any unusual symptoms occur.
112, 125, 137,
- Caution patient to avoid taking other
& 150 mcg. Pharmacokinetics:
medications concurrently with thyroid
Tablets: ABSORPTION: preparations unless instructed by health
25mcg, 50, 75, ● variably (40– 80%) care professional. Advise patient to take
88, 100, 112, absorbed from the 4 hrs apart from antacids, iron, and
125, 137, 150, GI tract calcium supplements.
175, 200, & DISTRIBUTION: - Instruct patient to inform health care
300 mcg. ● Distributed into professionals of thyroid therapy.
Powder for most body tissues - Emphasize importance of follow-up
injection: 100, exams to monitor effectiveness of
METABOLISM & therapy. Thyroid function tests are
200, & EXCRETION:
500mcg/vial. performed at least yearly.
● Metabolized by liver
and other tissues to
Contents:
active T3.
Each tablet
● Thyroid hormone
contains 100
undergoes
micrograms
enterohepatic
Levothyroxine
recirculation and is
sodium
excreted in the feces
anhydrous
via the bile
References:
Jones & Bartlett Learning. (2015). 2015 nurse's drug handbook (14th ed.). Jones & Bartlett Publishers.
Karch, A. M. (2013). 2014 Lippincott's nursing drug guide. Lippincott Williams & Wilkins.
Kizior, R. J., & Hodgson, B. B. (2018). Saunders nursing drug handbook 2019. Saunders.
Vallerand, A. H., & Sanoski, C. A. (2018). Davis's drug guide for nurses (16th ed.).
PRODUCT ASSESSMENT RUBRICS FOR DRUG STUDY
Student Name: _ Rasheed Osorio__________________ Year/Section: _ BSN 4 – A_______________ Date: _ January 30, 2023_______ Score: ___/30
Directions: Please select the appropriate rating using the following descriptions.
Side Effects ☐ Accurately presented all of the common side effects related to ☐ Accurately presented most of the common side effects ☐ Accurately presented some of the common side effects related
(10%) the drug. [3] relatedto the drug. 1-2missinginformationor errorsnoted.[2] to the drug. 3 or more missing information or errors noted. [1]
Nursing ☐ Accurately presented all of the common ☐ Accurately presented most of the common nursing ☐ Accurately presented some of the common nursing
Responsibilities nursing responsibilities (before, during, and after) related to the responsibilities related to the drug. 1-2 missing information or responsibilities related to the drug. 3 or more missing information
(30%) drug. [9] errors noted. [7] or errors noted. [3]
☐ Presented only one source that is updated (within 5 years),
References ☐ Presented at least 2 sources that are updated (within 5 years), ☐ No source was presented. Sources are not updated (more than 5
relevant, and credible. Other sources are not updated, credible
(10%) relevant, and credible. [3] years), relevant, and credible. [1]
or relevant. [2]
Sub-score = ____ = ____ = ____
Evaluated by:
_____ _______________ _______
Signature over Printed Name of Clinical Instructor