1.8 Mutations

EXEMPLAR LESSON PLAN
QUARTER/DOMAIN
GRADE 3RD QUARTER
March 27, 2023 PAGE NO. 1
LEVEL 10 LIVING THINGS AND THEIR
ENVIRONMENT
I. OBJECTIVES
A. Content The learners should be able to demonstrate the understanding of how
Standards mutations that occur in sex cells are transmittable
B. Performance
Standards
C. Learning Explain how mutations may cause changes in the structure and function
Competencies of a protein (S10lt-Iiie-38)
/
Objectives The Learners should be able to:
1. Differentiate the kinds of gene and chromosomal mutations

2. Illustrate kinds of chromosomal mutations
3. Recognize common chromosomal abnormalities and how to
respond to them.
II. CONTENT
III. LEARNING
RESOURCES
A. References
1. Teacher’s
Guide pages
2. Learner’s Science 10 Learners material pages 273 - 281
Material Pages
3. Textbook  Science Links 10 (2017) REX Book Store. 10 th Edition. Pages 245 -
pages 248
 Science and Technology 10 (2014) Vibal Group. Pages 227 - 231
 Practical Science 10 (2018) Diwa Learning Town. Pages 187 - 194
4. Additional
Materials from
Learning
Resource (LR)
portal
5. Other Learning Power Point Presentation
Resources
IV. PROCEDURES
A. Reviewing ACTIVITY 1: Human Base Pairing
Previous Lesson Directions
or presenting 1. The class will be divided into 2 with 8 representative each.
the new lesson. 2. The students will have a paper pasted on their backs
3. The teacher will present the DNA template and the students will align
their selves as complimentary bases.
4. The group who gets more correct pairing within two minutes wins.
Ex.
DNA template: ATGCCTAG
T A C G G A T C
B. Establishing a State the lesson objectives

purpose for the
lesson Present the following pictures and ask the students what product has
C. Presenting these kinds of labels.
examples/
instances of the Have the students look for amino acids on the labels. Ask what is the
new lesson role of Amino Acid in the human body.
Ask the students whether they have prior knowledge of how Amino
Acids are used to make proteins.
D. Discussion new Introduce what protein synthesis is.

concepts and
practicing new
skills # 1
Discuss Transcription and Translation

Let the students watch a video about the steps of Protein Synthesis:
RNA Transcription and Translation
Video Link: https://www.youtube.com/watch?v=gG7uCskUOrA
Guide Questions
1. Where do Transcription happen in human cell?
2. How RNA polymerase initiates Transcription?
3. What is the role of DNA strand in Transcription?
4. Where do Translation happen in human cell?
5. What is the function of ribosome in Translation?
6. What is the role of mRNA and tRNA in translation?
7. How amino acids are arranged?
E. Discussion new Activity 2: Using the illustration, arrange the steps of RNA
concepts and Transcription and Translation. Number accordingly.
practicing new
skills # 2
Number Steps
2 Nucleotides move into place along one of the strands
1 DNA is unzipped by the Enzyme RNA polymerase. The
two strands uncoil and separate
3 RNA polymerase assembles the complementary base
pairings
5 mRNA exits nucleus and moves to cytoplasm
4 mRNA separates from the DNA and the DNA is zipped up
by the RNA polymerase
7 Peptide bond is formed between amino acids attached
to tRNA
6 Ribosomes binds to the mRNA, reads mRNA by codon,
and draws tRNA with specific anti-codon
8 tRNA detaches from the amino acid and ribosome
9 Another amino acid is brought in until ‘stop’ codon is
reached.
F. Developing Discuss the Genetic codes for Amino Acid.

mastery (leads
to Formative
Assessment)
Activity 3: Decode the Code

Direction: Given the DNA template strand, write the complimentary
base pairs for mRNA and tRNA, and identify its specific amino acid.
G. Finding Practical Elicit the importance of Protein in the body using the following
applications of illustrations and questions.
concepts and Guide Questions
skills in daily 1. Protein is made of of chain of _____?
living 2. What are some of the roles of proteins in the body?
3. Where can you acquire protein?
H. Making Summarize the lesson using the following illustrations and key
generalizations concepts
and
abstractions  Amino acids are the building block of proteins
about the  Transcription and translation are the two processes of
lesson producing protein form DNA
 The three kinds of RNA in Protein Synthesis are Messenger RNA
(mRNA), Ribosomal RNA (rRNA), and Transfer RNA (tRNA)
I. Evaluating QUIZ: Multiple Choice
Learning 1. Which of the following does not exist in RNA
a. C
b. T
c. U
d. A
3. What does mRNA do?
a. Carry information from genes to ribosomes
b. Carry amino acids to ribosomes
c. Help with DNA unwinding
d. Make up ribosomes
3. Given the mRNA sequence AUGGGGUUAUACGUAG, the anti-codon
on the tRNA attaches to the first codon is?
a. TAC
b. UAC
c. UTC
d. ATC
4. The following are roles of protein in the body except?
a. Provides energy
b. Support cell structure
c. Transport substances in the bloodstream
d. Makes blood thin
5. Which of the following are signs of Protein deficiency?
a. Hair thinning, faded color, hair loss
b. Brittle nails
c. Loss of muscle mass
d. All of the above
J. Additional ACTIVITY: Transcription vs Translation
activities for Direction: Check the box corresponding to term needed to complete the
Application or sentence correctly.
remediation
V. REMARKS
VI.REFLECTION
A. No. of learners who earned 80% in
the Evaluation
B. No. of learners who require
additional activities for remediation
C. Did the remedial lessons work? No.
of learners who have caught up with
the lesson
D. No. of learners who continue to
require remediation
E. Which of my teaching strategies
worked well? Why did this work?
F. What difficulties did I encounter
which my principal or supervisor can
help me solve?
G. What innovation or localized
materials did I use/discover which I
wish to share with other teachers?
Prepared by:
LADYLEE B. ACUÑA
Practice Teacher
Checked by:
FLORENDA L. MORTEL
Master Teacher II

1.8 Mutations

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EXEMPLAR LESSON PLAN

1. Differentiate the kinds of gene and chromosomal mutations

B. Establishing a State the lesson objectives

D. Discussion new Introduce what protein synthesis is.

Discuss Transcription and Translation

F. Developing Discuss the Genetic codes for Amino Acid.

Activity 3: Decode the Code

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