Science 10
Science 10
Science 10
Quarter3_MELC#15&16_WEEK 4
Activity Sheet No. 4: Explain how protein is made using
information from the DNA; Explain how mutation
causes changes in the structure and function of a
protein.
START UP
CAPTURE
Proteins are large class of biomolecules consisting of chains of amino acid called
polypeptides. Proteins are synthesized by the cell and it is required for the
structure, function, and regulation of the body’s cells, tissues and organs. Protein
synthesis is the process in which cells makes protein. It occurs in two stages:
INTEGRATE
Materials:
Bond paper glue Colored paper
Genetic code table scissors DNA structure template
What to do:
1. Construct a DNA structure using your DNA structure template, bond
paper and colored paper (Red – guanine, Blue – cytosine, Yellow –
adenine, Green – thymine) based on the sequence below.
DNA Template Strand Sequence:
TAC-TTT-CGC-GAA-ACC-CCT-
2. After creating your DNA; use the DNA template strand sequence to
construct your mRNA (Red – guanine, Blue – cytosine, Yellow – adenine,
Pink – uracil)
3. Paste your constructed DNA and mRNA on a separate bond paper.
4. Using your mRNA codons (3 nucleotide sequence), write the
complementary anticodon (3 nucleotide sequence complimentary to
codon) amino acid sequence (refer to the genetic code table) on the box
provided below.
mRNA(codon)
tRNA(anticodon)
5. Repeat step 4 for the given mutated DNA sequences. Write your answer
on the space provided
TAC-TTT-CGC-GAA-ACC-CCT-
TCT-ATC
b.
TAC-TTT-CGC-GAA-ATT-CCT-
TCT-ATC
c.
sequence____________
TAC-GTT-TCG-CGA-AAC-CCC-
TTC-TAT-C
Answer the following. Write your answers on the line provided for each number.