Nervous System Part 2

Nervous System (Part II)
The Peripheral Nervous System

(PNS)
Peripheral Nervous System (PNS)
• All neuronal structures outside the central nervous

system (the brain and the spinal cord) is called PNS.
• The main function of the PNS is to connect the CNS
to the limbs and organs, by receiving data (such as
sight or sounds) and sending it to the CNS for
processing. The CNS in response to this data sends
commends to respond to the input.
The stimulus
conducts to the
spinal cords by
sensory neuron.
In the spinal
cord the
stimulus is
processed and
transmitted to
the skeletal
muscle.
• The afferent division of the peripheral nerve
fiber delivers information to the CNS and the
efferent division carries the motor
commands to the organs systems and muscles
of the body.
• The PNS not protected by bone of spine and

skull or by blood brain barrier.
• PNS consists of the;
1. Sensory Receptors.
2. Peripheral nerve fibers.
3. Ganglia.
4. Effector organ (skeletal muscle,
gland, smooth muscle, cardiac
muscle).
Sensory Receptors
• These are specialized receptors. Their function is
to respond to stimuli (changes in their
environment).
• Examples on sensory receptors are;
1. Mechanoreceptors – respond to touch, pressure,
itch ….ect.
2. Thermoreceptors – sensitive to changes into
temperature.
3. Photoreceptors – respond to light.
4. chemoreceptors – respond to changes in blood
chemistry, smell.
Nerve
• A nerve is a cord composed of numerous nerve fibers

(axons) bound together by connective tissue.
• Most nerves are mixtures of afferent and efferent fibers.
• Pure sensory (afferent) and pure motor (efferent) nerves
are rare.
• Peripheral nerves classified as cranial or spinal nerves.
.
Nerve
fiber
Nerve
fiber
Ganglia
• Synapse between nerve cells outside the CNS is
called ganglion
Synapse between two neurons
Parts of PNS
Peripheral
Nervous System
(PNS)
Somatic Nervous System Autonomic Nervous System

(SNS) (ANS)
Sympathetic Parasympathetic
Nervous System Nervous System
Somatic Nervous System (SNS)
• Mediate bodily movement.
• The somatic system is under conscious
control with signal that originate in the cortex.
• Innervate skeletal muscles.
• Also called voluntary nervous system, the somatic
system includes many involuntary functions such
as sensation and reflexes.
• Motor somatic neurons have No intermediate
synapses outside of CNS (one neuron
pathway i.e. there is No ganglia).
• Localized synapses are formed at specific
neuromuscular junction.
• Activation of motor somatic nerve leads to
muscle contraction (i.e. has excitation
effect only).
• One type of neurotransmitter (acetylcholine
“Ach”) releases at neuromuscular junction
Autonomic Nervous System (ANS)
• Mediates control of the internal organs.
• The autonomic system is largely involuntary, its control
originates in the brainstem and hypothalamus.
• Autonomic nervous system innervates the heart,
smooth muscles, organs and glands.
• The autonomic system makes one ganglion after
leaving the CNS. The post ganglionic cell then makes
contact with target organ (two neuron pathway).
• Stimulation can cause either excitation or inhibition
of the target tissue.
• Use several types of neurotransmitter like
norepinephrine (NE) and Ach.
Somatic nervous system Parasympathetic system
Differences between parts of PNS
Divisions of ANS
1. Sympathetic division
2. Parasympathetic division
• Almost, all visceral organs are innervated by

both divisions but they cause opposite effect.
ANS Anatomy
• The origin of sympathetic fibers is thorocolumber
region of the spinal cord while parasympathetic fibers are
originated from brain and sacral spinal cord
(craniosacral).
• The length of pre-ganglionic sympathatic fibers are short,

but post-ganglionic sympathetic fibers are long.
• In contrast pre-ganglionic parasympathetic fibers are

long and post ganglionic parasympathetic fibers are
short.
• The ganglia in sympathetic system are located close to the

to the spinal cord, but in parasympathetic system the
ganglia located near the viscera (organ).
ANS anatomy
• The origin of sympathetic fibers is thoracolumber region of
the spinal cord. While parasympathetic fibers are originated
from brain and sacral spinal cord (craniosacral).
• The preganglionic sympathetic fibers are short but post

ganglionic sympathetic fibers are long. While preganglionic
parasympathetic fibers are long and post ganglionic
parasympathetic fibers are short.
• The ganglia lie close to spinal cord in case of sympathetic

system but in the parasympathetic system the ganglia lie
near the target organ.
Neurotransmitters in the ANS
• ANS preganglionic axons release Ach (cholinergic
fibers).
• All parasympathatic postganglionic axons release Ach.
• Sympathetic postganglionic axons norepinephrine

(adrenergic fibers).
• Sympathetic nervous system has an excitatory effect
while parasympathetic nervous system has an inhibitory
Role of sympathetic system
• Mobilizes the body during activity; is the “fight or
flight” system.
• Promotes adjustments during exercise or when

threatened:
1. Blood flow is shunted to the skeletal muscles and heart.

2. Bronchioles dilate.
3. Liver releases glucose.
Role of parasympathetic division
• It promotes maintenance activities and
conserve body energy.
• Its activity is illustrated in a person who
relaxes or at rest, and after meal;
1. Blood pressure, heart rate, and respiratory
rates are low.
2. GIT activity is high.
3. Pupils are constricted and lenses are
accommondated for close vision.

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Nervous System (Part II)

The Peripheral Nervous System

• All neuronal structures outside the central nervous

• The PNS not protected by bone of spine and

• A nerve is a cord composed of numerous nerve fibers

Somatic Nervous System Autonomic Nervous System

• Almost, all visceral organs are innervated by

• The length of pre-ganglionic sympathatic fibers are short,

• In contrast pre-ganglionic parasympathetic fibers are

• The ganglia in sympathetic system are located close to the

• The preganglionic sympathetic fibers are short but post

• The ganglia lie close to spinal cord in case of sympathetic

• All parasympathatic postganglionic axons release Ach.

• Sympathetic postganglionic axons norepinephrine

• Promotes adjustments during exercise or when

1. Blood flow is shunted to the skeletal muscles and heart.

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