September 24, 2016

CINA Deluxe Data Quality Profile

Date DQP produced: September 23, 2016

Variable examined: Radiation Therapy (NAACCR Data Item #: 1360 and 1570)

Filters: Invasive cases only; excluded lymphoma, leukemia, DCO, and autopsy cases

Diagnosis Years covered: 2009-2013

Cancer Sites: Rectum, lung, female breast, prostate, and cervix

Database citation: CINA Analytic File, 1995-2013, Expanded Races

Number of Registries included: 48 State Registries plus DC Cancer Registry (Three registries

including Minnesota, Nevada, and New Mexico that did not meet the NAACCR data quality for

years 2009 to 2013 were excluded.)

Data Dictionary: NAACCR Data Dictionary 15

(http://www.naaccr.org/LinkClick.aspx?fileticket=xSH32ZzIzGI%3d&tabid=133&mid=473)

Members: Meichin Hsieh, Bin Huang, Ahmedin Jemal, Carol Kruchko, Xiangrong Li, Baozhen

Qiao, Recinda Sherman, Helmneh Sineshaw, Brad Wohler, Manxia Wu, Xiaocheng Wu,

Qingzhao Yu

Contact Information:

Meichin Hsieh, PhD, MSPH, CTR

Phone: (504) 568-5850
Email: [email protected]

Technical Notes:

1. The radiation status was created based on two radiation related treatment data items: RX

Summ—Radiation (NAACCR#: 1360) and RX Summ--Rad Regional RX Modality

(NAACCR#: 1570). The unknown radiation was based on both radiation related treatment

data items with unknown or blank values.

1
 September 24, 2016

2. Upper Whisker: extends to largest data point within the boundary of Q3 + 1.5* (Q3-Q1).

3. Diagnostic confirmation: Microscopic confirmed includes positive histology, positive

cytology, and positive microscopic confirmation, method not specified.

4. Type of reporting source: Hospital includes hospital inpatient, radiation treatment

centers/medical oncology centers, and other hospital outpatient units/surgery centers.

5. Urban/Rural 2013: The definition of metropolitan area is based on county using 2013

Rural/Urban Continuum Code. Metropolitan area include county metro area with population

≥ 1million, county metro area with population between 25,000 and 1 million, and county

metro area with population <25,000.

2
 September 24, 2016

Table 1. Unknown radiation by cancer site, Years 2009-2013 combined.

Rectum Lung Breast Prostate Cervix

Registry Level
25-75% Percentile (IQR) 0.6-3.4% 0.8-3.0% 0.8-3.5% 0.8-5.6% 0.5-3.0%
Minimum 0.0% 0.0% 0.0% 0.0% 0.0%
Mean 2.4% 3.1% 2.5% 4.4% 2.8%
Median 1.7% 1.7% 1.7% 3.1% 1.3%
Maximum 14.0% 40.2% 10.3% 35.8% 37.0%
Upper Whisker1 7.6% 6.3% 7.5% 12.7% 6.8%
# outside of upper whisker 2 6 2 3 5
Total Total % Total Total Total
All cases combined % Unk % Unk % Unk % Unk
Count Count Unk Count Count Count
Sex
Male 83,741 2.3 534,925 2.9 - - 970,236 4.2 - -
Female 58,878 2.5 474,379 2.7 1,079,677 2.4 - - 59,714 2.6
Race
White 116,882 2.1 867,827 2.8 899,109 2.3 759,790 3.5 45,565 2.4
Black 16,477 2.9 108,354 2.6 125,939 2.7 150,810 3.9 9,798 2.4
AI/AN 962 1.7 5,019 2.8 5,223 2.5 3,677 2.7 552 3.3
Asian or Pacific Islander 6,139 3.2 24,302 2.7 39,445 2.2 20,265 4.3 2,754 1.8
Unknown race 2,159 13.2 3,802 6.7 9,961 9.4 35,694 18.9 1,045 12.6
Age
00-49 years 20,465 2.2 41,386 2.0 211,660 2.3 28,178 3.1 29,939 2.6
50-64 years 55,258 2.4 285,430 2.4 397,760 2.3 396,307 3.3 18,088 2.2
65-74 years 32,967 2.3 336,975 2.6 252,572 2.3 366,966 4.0 6,756 2.4
75+ years 33,929 2.5 345,513 3.5 217,685 2.9 178,785 6.5 4,931 3.7
Dx Confirmation2
Microscopic confirmed 140,496 2.2 917,975 1.8 1,069,735 2.3 949,719 3.9 58,642 2.2
Non-microscopic
confirmed 1,315 4.6 71,271 4.3 5,749 9.6 10,441 4.5 392 7.9
Unknown 808 36.1 20,058 43.3 4,193 40.5 10,076 32.8 680 27.1
Type of reporting source3
Hospital 136,709 1.6 979,450 2.0 1,052,141 2.1 855,034 2.2 57,697 1.8
Non-hospital 5,910 19.9 29,854 30.0 27,536 16.4 115,202 19.0 2,017 24.8
Urban/Rural 20034
Metro 116,254 2.2 813,920 2.4 918,411 2.3 810,187 4.0 50,366 2.4
Non-Metro 25,656 3.0 191,116 3.9 156,881 3.3 154,805 4.3 9,104 2.8
Unknown 709 3.4 4,268 37.2 4,385 6.2 5,244 32.3 244 30.3
Derived SEER SS2000
Localized 60,517 1.8 196,082 1.7 681,048 1.9 748,186 2.8 25,842 1.8
Regional 45,643 0.8 234,495 1.7 308,912 2.2 110,344 1.7 21,464 1.0
Distant 23,672 1.2 519,591 1.6 62,248 2.0 46,479 2.2 8,525 1.4
Unknown 12,787 13.0 59,136 21.6 27,469 20.2 65,227 25.0 3,883 18.5

3
 September 24, 2016

Figure 1
% Unknown Ratiation Therapy by Registry
Rectal Cancer, 2009-2013
50

40

30
% Unknown

20

10

2.38

0
28 40 37 2 19 27 35 6 39 15 14 30 4 17 32 20 38 11 22 8 5 43 3 25 31 49 18 45 34 41 44 9 24 47 51 46 16 10 26 12 1 29 23 7 13 50 21 33 US

State Cancer Registry

4
 September 24, 2016

Figure 2
% Unknown Radiation Therapy by Registry
Lung Cancer, 2009-2013
50

40

30
% Unknown

20

10

2.81

0
28 19 39 2 6 32 14 35 20 30 27 37 34 8 5 25 15 22 3 4 18 11 17 38 51 31 16 26 24 41 7 9 40 29 1 43 50 45 10 49 46 47 12 13 23 33 21 44 US

State Cancer Registry

5
 September 24, 2016

Figure 3
% Unknown Radiation Therapy by Registry
Female Breast Cancer, 2009-2013
50

40

30
% Unknown

20

10

2.44

0
28 27 19 39 6 35 32 2 20 30 34 40 8 5 14 15 22 43 25 24 49 38 11 17 37 9 18 26 4 16 47 41 29 51 45 7 44 50 12 10 3 46 23 31 13 1 33 21 US

State Cancer Registry

6
 September 24, 2016

Figure 4
% Unknown Radiation Therapy by Registry
Prostate Cancer, 2009-2013
50

40

30
% Unknown

20

10

4.17

0
28 19 35 6 39 2 15 20 27 32 14 17 30 34 4 40 41 5 11 24 38 37 22 45 7 31 8 47 3 18 49 43 26 51 9 25 10 16 46 13 1 29 12 50 23 33 21 44 US

State Cancer Registry

7
 September 24, 2016

Figure 5
% Unknown Radiation Therapy by Registry
50
Cervical Cancer, 2009-2013

40

30
% Unknown

20

10

2.56

0
2 28 40 39 27 19 32 6 20 14 35 5 30 8 11 4 15 25 17 22 49 37 38 45 34 16 47 10 41 43 24 3 31 9 29 18 12 1 7 26 13 46 23 50 33 21 51 44 US

State Cancer Registry

8
 September 24, 2016

Table 2. Unknown radiation by diagnosis year: Rectal cancer 2009-2013

2009 2010 2011 2012 2013

Registry Level
25-75% Percentile (IQR) 0.2-2.1% 0.0-2.3% 0.4-2.8% 0.9-4.7% 0.7-4.2%
Minimum 0.0% 0.0% 0.0% 0.0% 0.0%
Mean 1.6% 1.5% 2.1% 3.3% 3.6%
Median 0.7% 1.2% 1.1% 2.3% 2.4%
Maximum 11.2% 6.8% 18.4% 17.0% 21.9%
Upper Whisker1 4.9% 5.6% 6.4% 10.4% 9.5%
# outside of upper whisker 4 4 3 3 6
Total Total Total Total Total
All cases combined % Unk % Unk % Unk % Unk % Unk
Count Count Count Count Count
Sex
Male 16,877 1.7 16,477 1.6 16,494 1.9 16,889 3.1 17,004 3.1
Female 11,933 1.8 11,801 1.7 11,762 2.1 11,613 3.6 11,769 3.5
Race
White 23,834 1.5 23,181 1.5 23,171 1.7 23,385 2.9 23,311 2.8
Black 3,310 2.2 3,373 1.7 3,184 2.2 3,191 4.6 3,419 3.7
AI/AN 203 1.5 161 0.6 183 1.1 203 1.5 212 3.3
Asian or Pacific Islander 1,085 2.7 1,208 1.7 1,305 4.1 1,242 3.6 1,299 3.8
Unknown race 378 9.3 355 12.1 413 9.9 481 14.6 532 18.2
Age
00-49 years 4,243 1.8 4,071 1.4 3,994 1.5 4,084 2.9 4,073 3.1
50-64 years 10,749 1.8 10,820 1.5 10,983 2.1 11,170 3.2 11,536 3.4
65-74 years 6,612 1.4 6,463 1.9 6,403 1.9 6,733 3.3 6,756 3.1
75+ years 7,206 1.9 6,924 1.7 6,876 2.1 6,515 3.7 6,408 3.1
Dx Confirmation2
Microscopic confirmed 28,412 1.6 27,851 1.4 27,816 1.7 28,054 3.1 28,363 3.1
Non-microscopic
confirmed 253 4.3 255 5.5 260 2.7 280 6.1 267 4.1
Unknown 145 33.8 172 33.1 180 36.7 168 42.3 143 34.3
Type of reporting source3
Hospital 27,123 1.2 27,194 1.2 27,166 1.1 27,449 2.3 27,777 2.3
Non-hospital 1,687 10.5 1,084 13.8 1,090 22.9 1,053 29.4 996 29.3
Urban/Rural 20134
Metro 23,393 1.7 23,038 1.4 23,027 1.8 23,316 3.2 23,480 3.2
Non-Metro 5,261 2.1 5,117 2.7 5,086 2.8 5,042 3.9 5,150 3.5
Unknown 156 1.9 123 0.8 143 2.8 144 6.3 143 4.9
Derived SEER SS2000
Localized 12,927 1.2 12,186 1.1 11,823 1.4 11,869 2.7 11,712 2.8
Regional 8,579 0.8 9,038 0.5 9,068 0.4 9,415 1.0 9,543 1.1
Distant 4,620 0.8 4,550 0.8 4,722 0.9 4,732 1.9 5,048 1.7
Unknown 2,684 9.2 2,504 10.0 2,643 11.8 2,486 17.9 2,470 16.8

9
 September 24, 2016

Table 3. Unknown radiation by diagnosis year: Lung cancer 2009-2013

2009 2010 2011 2012 2013

Registry Level
25-75% Percentile (IQR) 0.4-2.0% 0.3-2.0% 0.4-2.2% 1.2-4.2% 1.0-3.4%
Minimum 0.0% 0.0% 0.0% 0.0% 0.0%
Mean 1.7% 1.6% 2.0% 5.3% 4.9%
Median 1.1% 1.0% 1.0% 2.5% 2.4%
Maximum 8.1% 6.7% 11.0% 99.5% 99.0%
Upper Whisker1 4.4% 4.4% 4.8% 8.8% 7.1%
# outside of upper whisker 6 5 7 5 5
Total Total Total Total Total
All cases combined % Unk % Unk % Unk % Unk % Unk
Count Count Count Count Count
Sex
Male 108,795 2.3 106,824 2.0 106,694 2.2 106,851 4.1 105,761 3.8
Female 94,785 2.2 93,858 1.9 94,184 2.0 95,890 3.9 95,662 3.7
Race
White 175,792 2.3 172,911 1.9 172,820 2.1 173,881 4.0 172,423 3.8
Black 21,590 1.7 21,459 1.9 21,596 1.9 22,037 3.9 21,672 3.4
AI/AN 946 2.7 1015 0.9 995 1.8 1013 4.1 1,050 4.5
Asian or Pacific Islander 4,536 1.9 4,637 1.4 4,809 2.0 5,034 4.1 5,286 3.7
Unknown race 716 6.7 660 4.8 658 5.0 776 8.5 992 7.5
Age
00-49 years 9,620 1.7 8,765 1.3 8,157 1.3 7,631 3.0 7,213 3.2
50-64 years 56,819 1.9 56,866 1.6 57,393 1.7 57,579 3.7 56,773 3.3
65-74 years 66,956 1.9 65,658 1.6 66,518 1.8 68,634 3.8 69,209 3.6
75+ years 70,185 2.9 69,393 2.6 68,810 2.8 68,897 4.7 68,228 4.4
Dx Confirmation2
Microscopic confirmed 184,521 1.1 182,365 0.9 182,953 1.0 184,124 3.0 184,012 3.1
Non-microscopic
confirmed 14,722 3.9 13,852 3.1 13,834 3.9 14,496 5.4 14,367 5.3
Unknown 4,337 45.8 4,465 41.1 4,091 45.1 4,121 44.8 3,044 38.6
Type of reporting source3
Hospital 193,711 1.2 194,980 1.0 195,639 1.2 197,760 3.2 197,360 3.2
Non-hospital 9,869 22.1 5,702 31.4 5,239 34.5 4,981 36.5 4,063 33.1
Urban/Rural 20134
Metro 164,329 2.0 161,833 1.6 161,694 1.6 163,153 3.4 162,911 3.2
Non-Metro 38,373 3.3 38,010 3.3 38,360 4.1 38,723 4.8 37,650 4.1
Unknown 878 0.8 839 1.2 824 2.1 865 88.0 862 91.9
Derived SEER SS2000
Localized 39,383 0.9 37,732 0.7 38,539 0.8 39,812 2.9 40,616 2.9
Regional 46,936 0.9 46,797 0.8 46,840 0.9 47,005 3.0 46,917 3.1
Distant 102,797 0.9 103,638 0.8 103,548 0.9 104,950 2.7 104,658 2.7
Unknown 14,464 19.5 12,515 19.0 11,951 21.3 10,974 26.1 9,232 23.6

10
 September 24, 2016

Table 4. Unknown radiation by diagnosis year: Female breast cancer 2009-2013

2009 2010 2011 2012 2013

Registry Level
25-75% Percentile (IQR) 0.3-1.8% 0.2-2.1% 0.3-2.9% 1.0-4.9% 1.7-5.9%
Minimum 0.0% 0.0% 0.0% 0.0% 0.0%
Mean 1.3% 1.4% 1.9% 3.7% 4.1%
Median 0.7% 0.6% 0.8% 2.4% 3.0%
Maximum 10.1% 6.8% 9.5% 15.6% 13.5%
Upper Whisker1 4.1% 4.8% 6.7% 10.7% 12.2%
# outside of upper whisker 3 2 3 5 2
Total Total Total Total Total
All cases combined % Unk % Unk % Unk % Unk % Unk
Count Count Count Count Count
Race
White 178,344 1.7 174,389 1.4 179,636 1.7 181,859 3.4 184,881 3.5
Black 24,104 1.8 24,226 1.6 25,409 1.7 25,642 4.0 26,558 4.2
AI/AN 940 1.8 950 0.8 1087 2.6 1071 3.5 1,175 3.5
Asian or Pacific Islander 6,881 1.1 7,503 1.3 7,929 1.7 8,341 3.6 8,791 3.0
Unknown race 1,759 7.9 1,759 6.2 1,753 6.6 2,149 12.8 2,541 11.8
Age
00-49 years 43,825 1.7 41,847 1.3 42,372 1.6 41,879 3.6 41,737 3.6
50-64 years 77,667 1.6 77,247 1.3 80,103 1.6 80,550 3.4 82,193 3.5
65-74 years 46,664 1.5 46,856 1.4 49,731 1.7 53,054 3.2 56,267 3.5
75+ years 43,872 2.0 42,877 2.1 43,608 2.3 43,579 4.2 43,749 4.1
Dx Confirmation2
Microscopic confirmed 209,768 1.5 206,734 1.3 213,845 1.5 217,124 3.4 222,264 3.5
Non-microscopic
confirmed 1,377 7.3 1,163 7.2 1,077 8.3 1,113 13.2 1,019 13.1
Unknown 883 41.3 930 37.7 892 39.2 825 42.8 663 42.4
Type of reporting source3
Hospital 203,098 1.4 203,904 1.1 211,237 1.3 214,469 3.2 219,433 3.3
Non-hospital 8,930 9.3 4,923 17.7 4,577 19.9 4,593 20.5 4,513 21.5
Urban/Rural 20134
Metro 179,977 1.6 177,348 1.3 183,324 1.5 186,340 3.4 191,422 3.5
Non-Metro 31,204 2.3 30,520 2.6 31,640 2.9 31,820 4.4 31,697 4.5
Unknown 847 1.3 959 2.3 850 4.5 902 10.5 827 12.6
Derived SEER SS2000
Localized 131,235 1.1 129,792 1.0 136,319 1.2 139,529 2.9 144,173 3.0
Regional 62,737 1.4 61,143 1.1 61,487 1.4 61,685 3.6 61,860 3.5
Distant 11,840 1.4 12,230 1.2 12,535 1.2 12,763 3.1 12,880 3.0
Unknown 6,216 17.6 5,662 17.4 5,473 19.0 5,085 22.8 5,033 25.1

11
 September 24, 2016

Table 5. Unknown radiation by diagnosis year: Prostate cancer 2009-2013

2009 2010 2011 2012 2013

Registry Level
25-75% Percentile (IQR) 0.3-2.9% 0.2-4.1% 0.4-5.2% 1.3-7.8% 1.3-9.0%
Minimum 0.0% 0.0% 0.0% 0.0% 0.0%
Mean 2.2% 2.7% 3.3% 7.2% 7.5%
Median 0.9% 1.0% 1.9% 4.4% 3.2%
Maximum 16.7% 14.4% 17.7% 99.9% 99.6%
Upper Whisker1 6.7% 9.8% 12.3% 17.4% 20.5%
# outside of upper whisker 3 2 2 3 2
Total Total Total Total Total
All cases combined % Unk % Unk % Unk % Unk % Unk
Count Count Count Count Count
Race
White 167,498 2.6 160,521 2.3 163,837 2.7 136,507 5.3 131,427 5.4
Black 31,943 2.9 30,931 3.1 31,815 3.0 28,448 5.2 27,673 5.4
AI/AN 772 1.4 768 1.4 742 2.4 706 3.7 689 4.8
Asian or Pacific Islander 4,152 3.5 4,094 2.7 4,441 4.5 3,785 5.6 3,793 5.3
Unknown race 6,733 8.8 7,419 14.5 7,813 16.6 6,875 26.4 6,854 28.9
Age
00-49 years 6,589 2.7 6,046 1.9 6,065 2.1 5,098 4.8 4,380 4.8
50-64 years 86,207 2.3 83,096 2.0 86,201 2.4 72,039 5.2 68,764 5.3
65-74 years 77,791 2.7 75,994 2.8 78,153 3.1 67,975 5.9 67,053 6.2
75+ years 40,511 4.6 38,597 5.0 38,229 6.1 31,209 9.0 30,239 8.9
Dx Confirmation2
Microscopic confirmed 206,948 2.6 199,508 2.5 204,435 3.0 172,224 5.8 166,604 6.0
Non-microscopic
confirmed 2,065 3.6 2,051 4.0 1,998 3.1 2,133 6.0 2,194 5.7
Unknown 2,085 31.8 2,174 30.9 2,215 31.2 1,964 36.9 1,638 33.5
Type of reporting source3
Hospital 183,004 1.5 180,505 1.2 184,012 1.3 156,574 3.6 150,939 3.6
Non-hospital 28,094 11.6 23,228 15.6 24,636 18.2 19,747 26.5 19,497 27.2
Urban/Rural 20134
Metro 175,938 2.9 169,495 2.8 174,210 3.2 147,524 5.6 143,020 5.9
Non-Metro 34,006 2.8 33,116 3.1 33,336 3.9 27,834 6.3 26,513 6.2
Unknown 1,154 2.8 1,122 6.4 1,102 7.8 963 82.1 903 79.2
Derived SEER SS2000
Localized 165,968 1.3 158,777 1.7 162,473 1.9 134,685 4.9 126,283 5.2
Regional 22,393 0.7 22,638 0.7 23,480 0.8 20,813 3.5 21,020 3.4
Distant 8,488 1.4 8,821 1.3 9,169 1.5 9,714 3.6 10,287 3.2
Unknown 14,249 25.9 13,497 21.0 13,526 26.1 11,109 27.6 12,846 24.8

12
 September 24, 2016

Table 6. Unknown radiation diagnosis year: Cervix cancer 2009-2013

Table 5. Unknown radiation diagnosis year: Cervix cancer 2009-2013

2009 2010 2011 2012 2013
Registry Level
25-75% Percentile (IQR) 0.0-1.7% 0.0-1.6% 0.0-2.3% 0.6-4.3% 0.0-3.7%
Minimum 0.0% 0.0% 0.0% 0.0% 0.0%
Mean 1.5% 1.8% 1.5% 4.9% 4.2%
Median 0.4% 0.4% 0.7% 2.1% 1.6%
Maximum 14.1% 16.7% 9.8% 98.9% 100.0%
Upper Whisker1 4.3% 4.0% 5.6% 9.9% 9.1%
# outside of upper whisker 5 5 2 3 3
Total Total Total Total Total
All cases combined % Unk % Unk % Unk % Unk % Unk
Count Count Count Count Count
Race
White 9,512 2.3 9,041 1.5 9,195 1.6 9,002 3.4 8,815 3.3
Black 2,016 2.1 2,076 1.5 1,896 1.8 1,903 2.9 1,907 3.7
AI/AN 121 1.7 105 2.9 109 1.8 113 6.2 104 3.8
Asian or Pacific Islander 536 0.7 545 2.0 533 1.1 570 3.2 570 1.9
Unknown race 194 7.7 191 14.1 171 10.5 255 12.9 234 16.7
Age
00-49 years 6,432 2.3 6,026 1.6 5,944 1.6 5,865 3.9 5,672 3.8
50-64 years 3,555 2.0 3,657 1.6 3,585 1.5 3,674 2.7 3,617 3.4
65-74 years 1,347 1.8 1,300 2.1 1,375 2.1 1,341 3.3 1,393 2.7
75+ years 1,045 3.6 975 2.8 1,000 2.8 963 5.0 948 4.4
Dx Confirmation2
Microscopic confirmed 12,168 2.0 11,723 1.4 11,691 1.4 11,626 3.1 11,434 3.4
Non-microscopic
confirmed 70 7.1 72 4.2 70 7.1 90 6.7 90 13.3
Unknown 141 27.0 163 24.5 143 24.5 127 40.2 106 18.9
Type of reporting source3
Hospital 11,771 1.6 11,579 1.1 11,537 0.9 11,505 2.6 11,305 2.8
Non-hospital 608 16.0 379 20.1 367 28.1 338 36.1 325 31.4
Urban/Rural 20134
Metro 10,405 2.2 10,035 1.6 10,035 1.6 10,045 3.1 9,846 3.3
Non-Metro 1,923 2.7 1,864 2.2 1,820 2.1 1,755 3.8 1,742 3.4
Unknown 51 0.0 59 5.1 49 0.0 43 81.4 42 85.7
Derived SEER SS2000
Localized 5,495 1.5 5,257 0.9 5,068 0.8 5,070 2.9 4,952 3.3
Regional 4,465 0.9 4,240 0.6 4,261 0.3 4,273 1.5 4,225 1.8
Distant 1,597 1.1 1,625 0.4 1,745 0.9 1,764 2.2 1,794 2.2
Unknown 822 17.5 836 15.4 830 16.4 736 23.1 659 21.2

13