This document discusses various infections that can occur during pregnancy including urinary tract infections, vaginal infections, sexually transmitted infections, and outlines their causes, symptoms, risks and treatments. It also summarizes the risks of substance abuse during pregnancy including alcohol, tobacco, marijuana, cocaine and outlines management approaches.
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INFECTIONS
This document discusses various infections that can occur during pregnancy including urinary tract infections, vaginal infections, sexually transmitted infections, and outlines their causes, symptoms, risks and treatments. It also summarizes the risks of substance abuse during pregnancy including alcohol, tobacco, marijuana, cocaine and outlines management approaches.
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NCM 105
Instructor: Mrs. Glady’s Reina M. Maitem
INFECTIONS - Loss of protective Dx – vaginal or urine culture lactobacilli bacteria (aka DDH notifies partners A. URINARY TRACT vaginitis) Rx with Rocephin IM INFECTIONS - Thin, watery vaginal (ceftriaxone), Zithromax delivery with clue cells seen (azithromycin) 1 g single dose - Caused by: E. coli, under microscope vaginal for amoxicillin PO Klebsiella, Proteus pH >5 - S/S: Asymptomatic Tx: with flagus (metronidazole PID (Pelvic Inflammatory Bacteriuria = (+) bacteria in 500 mg BID x 7 days) avoid Disease) urine intake of alcohol similar to - Example: no symptoms Antabuse – severe - Cramping, fever, chills, Rx: Early pregnancy, oral - Risk factor for PROM purulent discharge, N/V sulfonamides Bactrim uterine swelling adnexal and - Late: Ampicillin, furoclantin TRICHOMONIASIS cervical tenderness - If left untreated, infection (“strawberry” cervix) - Multiple sex partners no led to acute, pyelonephritis - Different organism caused condoms by parasite trichomonas Tx with doxycycline i.o B. CYSTITIS (Lower UTI) vaginalis. Vaginal discharge (contraindicated in pregnancy) (thin, greenish, yellow and Rocephin IM S/S: Dysuria, urgency, discharge or foamy) clindamycin/gentamycin/Rocep frequency, low grade fever, - An STI hin if pregnant may need clean catch leukocytes >10,000 Same Tx as BV for PTL and hospitalization counts PROM - Same as UTI, occurs in HERPES (Herpes Genetalis) bladder F. STIs - Viral infection – no cure C. ACUTE (Chlamydia) - HSV 1 – oral (cold, sore) PYELONEPHRITIS outer lesion - Caused by: bacterium - HSV 2 – genital painful, - Infection of kidney, caused chlamydia trachomatous open lesion by same microorganisms - Most common STI in USA - Vesicles rupture and appear S/S: Chills, fever, flank pain, - Often asymptomatic: tight after exposure or dysuria, low urine thin/virulent discharge within 20 days burning and frequency with - Burning sensation with D. MONILIAL VAGINAL urination lower and pain urination is 1st sign INFECTION - Pregnant women: Zithromax - Prodrome “tingling” occurs 1 g single dose amoxicillin x before new outbreak - Caused by: 80% candid 7 days Dx: vaginal seen or blood test ablicans – caused by change Rx: acyclovir or Valtrex 500 mg in normal vaginal pH – pH NEWBORN once a day during pregnancy <5 – acidic CONJUNCTIVITIS reduces viral load enough to S/S: thick white discharge (erythromycin ointment) deliver vaginally severe itching dysuria. Wet neonatal pneumonia, PTL, fetal mount hyphae, budding yeast death, Perinatal transmission SYPHILIS: Treponema Risk factors: occurs in 50% infants where Palladium (Spirochete) - HIV, DM, pregnancy mom is infected at time of Tx: Intravaginal micronamole delivery - Primary stage: painless suppository at hours of sleep for sores “chancre”, 1week GONORRHEA (Endocrine approximately 2-3 weeks - Implication: fetus may Gonorrhea) after initial exposure, fever, contact thrush during malaise delivery - Caused by: Neisseria - Secondary stage: 6 weeks to - Infant with oral nystatin 1 cc Gonorrhea, Bacteria STI 6 months, skin eruptions, < every 6 hours - Can lead to PID > infertility arthritis, liver enlarged, sore - Teach: no douching; cotton green frothy discharge throat underwear - Often asymptomatic in Tx: females, males have burning - < 1 year 2.4 million E. BACTERIAL VAGINITIS with urination and penile benzathine penicillin x 1 - Overgrowth of gardenella damage dose IM (normal vaginal flora NCM 105 Instructor: Mrs. Glady’s Reina M. Maitem - > 1-year same medication 1 - Denial – guilt, fear of legal TOBACCO x per week x 3 weeks consequences, loss of - Impaired O2 delivery - Sexual partners screened for custody of children nicotine-induced treatment - History taking, maternal vasospasm, carbon - If allergic to penicillin tx testing after informed monoxide, other chemicals, ceftriaxone > 1 trimester st consent, etc. chromosomal instability - 40% chance of still birth or - Be sensitive and respectful lung development death > birth – infant may in interviewing - Preterm delivery, low birth be born with “congenital - Ask about frequency, time weight (<2,500 g), small for syphilis” of last use, route gestational age, PPROM, - Ophthalmia neonatorum: administration placenta previa, abruption, can cause blindness appears Risk factors: IUFD as conjunctivitis in newborn o Late prenatal care - SIDS, asthma, otitis media o Missed prenatal visit - Idiopathic mental GENITAL WARTS – virus - DOBHx: miscarriage, retardation, ADHD (aka Condyloma) IUGR, premature birth - Pharmacotheraphy to those - Child with unlikely to quit - Soft pink lessions on vulva, neurodevelopmental vagina, cervix, anus problems B. MARIJUANA “cauliflower appearance” - Child not living with mother - Most common illicit - HPM, type 6 and 1 cause History of drug substance used in pregnancy 90% of genital warts - Detectable in urine for - 120 strains HCV Management: weeks Tx: Trichloroacetic acid-aldara - Counselling - Adverse effects Category C - Social learners inconclusive: association - Benefits (pregnancy) maybe - Testing for stos with sleep disturbance acceptable over potential - Frequent prenatal visits, - Small fetal head circulation risk education - Decreased intelligence, - Contacts occur during - Early ultrasound autinomic loss stability vaginal birth. Infant may - Antepartum fetal - Betablockers have laryngeal warts surveillance contraindicated - Conforming pediatrics of - Leukemia, Gardasil Vaccine: 3 doses possible neonatal phadomyosarcoma - HPV Types 16 and 18 – withdrawal (80% cervical cancer) and C. COCCAINE types 6 and 11 (90% genital A. ALCOHOL - Crosses the placenta and warts) - No level is safe fetal blood-brain barrier - Can be given to males - Spontaneous abortions, - Vasoconstriction stillbirth due to fetoplacental hypertension deflection small for - Crack babies – tremors, high Substance Abuse gestational age – pitched cry, irritability, 4% of pregnant we elicit - ADHD, oppositional defiant excessive suck, substances disorder conduct disorder hyperalertness, autonomic Half of substance - Binge drinking disorder in stability abusing women continue adult offspring - Betablockers using during pregnancy - Future drinking problem contraindicated An even larger - Associated with delayed proportion Abule FETAL ALCOHOL cognitive, language tobacco or alcohol SYNDROME development Pregnant women DISORDER (FASD) typically lightly - Diagnostic criteria requires D. HEROINE motivated to modify all times - Pre-eclampsia, third behavior to help their - Growth problems trimester bleeding unborn child - Facial dysmorphia - Neonatal abstinence - Thin vermilion syndrome Screening - Short palpebral fissures - Increased autonomic - Substance abusers come - CNS abnormalities reactivity with withdrawal from all socioeconomic symptoms begin 24 hours statuses, ages and races after birth, 40 hours with NCM 105 Instructor: Mrs. Glady’s Reina M. Maitem methadone or organ damage d/t systemic If the two types of blood buprenorphine vasoconstriction mix, the body will make - Premature – reduced risk - Headache: visual changes; antibodies - Supportive therapy confusion, abdominal pain; S/S: severe anemia, liver - Methadone treatment impaired liver function with dysfunction, kidneys, severe - Bulimorphine hyperbilirubinemia; baby jaundice (management for oliguria; proteinuria; jaundice = phototherapy) Nursing Considerations: pulmonary edema; hemolytic anemia; RHOGAM Ask – at each visit thrombocytopenia; fetal - 28 weeks Advise – cessation growth retardation - 10 prevent from producing Assess – willingness - Eclampsia (seizures) may antibodies Assist – establish a plan follow - 11 prevent mother from Arrange – follow, being sensitize referrals, support Nursing Intervention: for a woman w/ mild PIH: GESTATIONAL DIABETES Clients with mild pre- AKA “GDM” PRE-ECLAMPSIA eclampsia can be - Glucose intolerance - BP > 140/90 managed at home with beginning in pregnancy’ - Presents with hypertension, fragment following care - GDM occurs 20th with no proteinuria, edema of face, Monitor antiplatelet incidence of anomalies hands ankles therapy - 2% have undiagnosed type - Occur anytime > 20th weeks Promote bed rest II entering pregnancy of pregnancy Promote good nutrition - Type 1&2 have anomalies - Usually occurs closer to due Provide emotional d/t organogenesis (1st date, will not resolve until support monitor FHR trimester) after birth can progress to Deliver close to EDC - 4% of pregnant affected help syndrome - Maternal Risk: HTN Monitor BP - Dip stick – to know if there disorders, polyhydramnios, is protein in urine macrosomia (c/s rate) BP: 160/90 – give magnesium o Diagnostic: to know - Infant risks: Birth trauma, sulfate IM @ buttocks if there is protein in shoulder dystocia, Antidote: calcium gluconate urine (+) hypoglycemia, - AC should be full blast o 24-hour urine hyperbilirubinemia, fetal - Turn on electric fan death collection - Icepacks o Greater than 5 grams Risk factors: is considered Drugs for Pre-eclampsia M – maternal age over 25 years proteinuria 1. Magnesium Sulfate – old muscle relaxant; O – overweigh >25 /obesity GENERAL SIGN OF PRE- prevents seizure >30 ECLAMPSIA (loading dose (4-6g M – Macrosomia (large babies) - Rapid weight gain; swelling maintenance dose > 9 lbs of arms/face 1-2g/hIV) M – multiple pregnancy - Headache; vison changes 2. Hydralazine – A – a history of previous of (blurred vision, feeling antihypertensive (5- GDA family Hx GDM double, seeing spots) 10mg/IV) administer - Dizziness /faintness/ ringing slowly to avoid sudden Screening & Diagnosis of of ears/confusion; seizures fall in blood pressure. GDM - Abdominal pain, decrease 3. Diazepam (Valium) – - Screen all women @ 24-28 production of urine: nausea, halt seizures (5-10 weeks vomiting blood or blood in mg/IV) - Higher risks patients urine 4. Calcium gluconate – screened in 1 semester/ 1st st antidote for magnesium prenatal visit and @ 24-28 Mild: intoxication (1g/IV – 10 weeks - mild HTN, no end-organ ml of a 10% solution) damage; minimal 1st do: proteinuria RH SENSATION - 1 hour glucose challenge Severe: - You may have Rh-negative test (GCT) – 50g oral - Significant HTN, severe blood and your baby may glucola no fasting needed proteinuria (>50 g/d); end you have Rh-positive blood. NCM 105 Instructor: Mrs. Glady’s Reina M. Maitem - Recommended GCT value - Teach monitoring of fasting <140 mg/dl (detects 80%) and post prandial levels - Follow GCT >/ = 140 mg/dl with diagnostic 8 hours. If diet can’t control glucose, GTT (glucose tolerance start insulin test) 100g. glucona - Regular and intermediate - Do fasting 1hr, 2hr, 3h acting insulin for breakfast serum. Fast at least 8 hours and dinner with at least 150g carb - Does not cross placenta intake 3 days prior to test & - Dose base in weight & normal activity level gestational age - Chose patients with GTT diagnostic Thresholds: increased dose
Drink 100g glucola levels every 2 hours (insulin given @ 100 mg per dl < 1 hour: 180 mg/dl plasma level 2 hours: 155 mg/dl Postpartum: most return to 3 hours: 140 mg/dl normal after delivery - Diagnosis of GDM if 2 or - 50 % patients with GDM more values than above develop type II later in life plasma levels - 6-weeks pp serum glucose - Children of GDM patients Management: increase for obesity in - May try standard diabetic childhood adolescence. diet 1st depending on lab values - Initiate insulin for fasting >95 and 2 hours postprandial - 120 mg/dL
Intervention: Antepartum
Goal: Strict glucose control
- Provide immediate education to patient or family - Standard diabetic diet (2000-2500 cal/day)