Upcat Reviewer Biology
Upcat Reviewer Biology
Upcat Reviewer Biology
❖ BIOMOLECULES
1. All living things are composed or made up of cells, which are the most basic unit
of life.
2. Cells are products of reproduction of pre-existing cells.
3. Cells pass hereditary information (DNA) to their offspring cells.
4. Cells have similar chemical compositions compared to other cells.
5. Cells are the sites of energy flow mechanisms such as respiration and
metabolism
❖ CELLS
PROKARYOTES vs. EUKARYOTES
PROKARYOTES EUKARYOTES
DNA is helix-shaped and
DNA is round and flows
straight, found in the
Genetic information freely in cytoplasm
nucleus
DNA, plasma membrane,
cytoplasm, nucleus and
membrane-bound
DNA, plasma membrane, organelles (ex:
nucleoid, cytoplasm mitochondria,
Organelles
chloroplasts(found only on
plant cells), Golgi body,
endoplasmic reticulum)
Can be found in plant and
fungal cells, but not
Present, composed of composed of
Cell wall
peptidoglycans peptidoglycans
Can’t be found in animal
cells
Size Small (1-5 µm) Larger (10-100 µm)
Animals, plants, fungi, and
Organisms Bacteria and archaea
protists
Can be unicellular or
Cell structure Unicellular
multicellular
1) Photosynthesis
● Light Reactions
● Calvin Cycle
Carbon fixation and reduction of RuBP by CO2 converts it into G3P, which
can be further processed into glucose.
The fixed and reduced RuBP is then converted back to be ready for the
next cycle; the whole cycle consumes ATP and NADPH.
2) Cellular Respiration
● Glycolysis
Breakdown of glucose and investment of 2 ATP to produce pyruvate, 4
ATP, and 2 NADH
● Pyruvate Oxidation
Pyruvate is oxidized into acetyl CoA, producing CO2 and transforming
NAD+ into NADH in the process.
● Citric Acid Cycle/Krebs Cycle
Acetyl CoA reacts with oxaloacetate, which undergoes another series of
reactions, reducing NAD+ into NADH, FAD+ into FADH2, ADP into ATP, and
producing CO2 ; 2 ATP is produced per molecule of glucose
❖ CELLULAR REPRODUCTION
Centrosome
contains material that functions in organizing mitotic spindles
Centromere
attachment point of two sister chromatids
Kinetochore
site of attachment of mitotic spindle to chromosomes
❖ ORGAN SYSTEMS
1) Digestive System
- Food processing involves ingestion (eating), digestion (breakdown), absorption
(uptake of nutrients), and elimination (passage out of the body).
2) Circulatory System
∙ 4 Heart Chambers: Left Ventricle, Right Ventricle,
Left Atrium, Right Atrium
∙ Blood Vessels
3) Respiratory System
Lungs - main organ of the respiratory system;
houses the bronchi, bronchioles, and alveoli
Air pathway:
Mouth/ Nose → Pharynx →Larynx → Trachea
→ Bronchi →Bronchioles → Alveoli
(where gas exchange takes place)
4) Immune System
includes lymphoid organs such as thymus,
spleen, tonsils, and bone marrow, the skin,
and specialized cells.
5) Excretory System
Kidney - carries out osmoregulation and
excretion of urea in mammals
Ureter - duct which transports urine from the
kidney to the bladder
Bladder - place where urine is stored before
excretion
Urethra - tube which urine from the bladder is
excreted
6) Reproductive System:
A. Male Reproductive System
Testes - male gonads, produce
sperm in the seminiferous tubules
Epididymis - site of sperm cell
storage and maturation
Vas Deferens - transports sperm
cells from the testes to the urethra
Seminal Vesicles - provide fluids
that constitute most of semen to
nourish the sperm cells
Prostate Gland - provides
anti-coagulant enzymes to the
semen
Bulbourethral Glands - produces
fluids that lubricate and neutralize
the acidity of the urethra
Scrotum - sac of skin that protects
and regulates the temperature of
the testicles
Penis - a series of muscular
erectile tissues that aid in sexual
intercourse
7) Nervous System
• Central Nervous System (CNS) - site of processing
of nerve impulses
• Peripheral Nervous System (PNS) - site of detection
and transmission of nerve impulses
• Neurons - nerve cells that carry impulses across the
body
Types of Neurons
Afferent Neurons - carry signals towards the CNS
Interneurons - present in CNS, pass signals from
afferent neurons to efferent neurons
Efferent Neurons - transmit signals from the CNS
towards the motor and sensory organs
8) Endocrine System
A. Anterior pituitary gland
Produces:
Thyroid stimulating hormone (TSH) – stimulates
thyroxin release from the thyroid gland
Luteinizing hormone (LH) – promotes estrogen
production, progesterone production, and
ovulation in females, promotes testosterone
release in males
Adrenocorticotropic hormone (ACTH) – promotes
hormone release by the adrenal cortex
Follicle stimulating hormone (FSH) – promotes the
development of eggs and follicles in females,
promotes testosterone production in males
Growth hormone (GH) – promotes growth of the
bones and muscles
Prolactin – promotes milk production in breasts
C. Thyroid gland
Produces:
• Thyroxine – increases energy expended during rest periods (basal metabolic
rate or BMR)
• Calcitonin – reduces blood calcium concentration levels
D. Hypothalamus
Produces:
• Thyrotropin-releasing hormone (TRH) – stimulates anterior pituitary gland
release of TSH
• Gonadotropin-releasing hormone (GnRH) – stimulates anterior pituitary gland
release of FSH and LH
• Growth hormone-releasing hormone (GHRH) – s stimulates anterior pituitary
gland release of GH
• Corticotropin-releasing hormone (CRH) – stimulates anterior pituitary gland
release of ACTH
• Somatostatin – decreases the amount of released GH and TSH
• Dopamine – decreases the amount of released prolactin, activates “reward
centers” of brain
E. Parathyroid gland
Produces:
• Parathyroid hormone (PTH) – increases calcium absorption in the small
intestine and increases calcium release rate from bones
F. Adrenal cortex
Produces:
• Cortisol – has anti-inflammatory properties, regulates the immune system
• Aldosterone – raises levels of sodium in the blood
G. Pancreas
Produces:
• Insulin – lowers blood sugar levels when necessary
• Glucagon – raises blood sugar levels when necessary
H. Adrenal medulla
Produces the stress hormones in a fight-or-flight situation:
• Adrenaline (epinephrine) – increases heart rate and blood sugar levels,
relaxes breathing muscles to improve breathing
• Noradrenaline (norepinephrine) – increases heart rate and blood sugar
levels, increases blood pressure by narrowing blood vessels
I. Pineal gland
Produces:
• Melatonin – regulates circadian rhythms or sleep cycles
J. Ovaries
Produces:
• Estrogen (e.g., estradiol) – primary female sex hormone; development of the
female reproductive system and secondary sex characteristics.
K. Corpus luteum
Releases:
• Progesterone – regulates the menstrual cycle and crucial for pregnancy
L. Testes
Produces:
• Androgens (e.g., testosterone) – causes development of secondary male
characteristics like sperm cell production
9) Musculoskeletal Systems
● Endoskeleton - internal skeleton of
chordates that consists of bones and
cartilage
● Tendons - attach the striated muscles to
bones
● Ligaments - connect bones together inside
joints
Types of muscles
Smooth Muscle - muscles found in internal organs,
involuntary action
Cardiac Muscle - muscles found in the heart,
involuntary action
Skeletal Muscle - muscles that aid in locomotion,
voluntary action
❖ GENETICS
1) Mendelian Genetics
GG x Gg
G g
G GG Gg
G GG Gg
G = green seeds (dominant)
g = yellow seeds (recessive)
2) Non-Mendelian Genetics
Incomplete Dominance
Heterozygous offspring have phenotypes that appear as an intermediate
between dominant and recessive types (e.g., pink flowers as offspring of white
and red flowers).
Codominance
Heterozygous offspring has phenotypes where both dominant and recessive
types are expressed (e.g., Roan cows have white and red patches even if its
parents are pure white and pure red cows).
Multiple Alleles
A gene still contains two alleles, but there are more than two types of alleles, with
different degrees of dominance (e.g., Blood Type alleles may be A, B, or O; A
and B have the same degree of dominance, but O is recessive).
Pleiotropy
A single gene affects different phenotypes (e.g., there is only one gene that
determines pea flower color and pea seed color).
Epistasis
A single phenotype is affected by two different genes (e.g., two genes need to
have a dominant allele for a Labrador to have yellow fur).
Polygenic Inheritance
A gene expression is not limited to two different traits but instead several degrees
of the trait (e.g., skin color is not just black or white, but different shades). Two or
more genes also contribute to the phenotype.
X-linked recessive
XY = Healthy male XCY = Affected male
XX = Healthy female XCXC = Affected female XCX = Carrier female
Purine Pyrimidine
Adenine (A) Thymine (T)
Guanine (G) Cytosine (C)
Applications of genetics
1. Paternity testing uses DNA to determine if a person is a parent of a child.
2. Mammalian gene expression is the production of genetic products (usually
proteins) from gene instructions.
3. Recombinant DNA technology involves joining DNA strands of two different
organisms to produce certain traits, such as parasitic resistance, in an organism.
4. Reproductive cloning involves creating an organism that is genetically identical to
a donor organism through somatic cell nuclear transfer.
Proofs of Evolution
1. Adaptive evolution (e.g., Bacteria become increasingly resistant to antibiotics
after long exposures.)
2. Homology – similarity due to common ancestry (e.g., All mammals have a large
bone connected to two smaller bones in their arms.)
3. Fossil records (e.g., Fossils found below the Earth are different from but related
to those that are living in the present.)
4. Molecular biology – DNA analysis show common DNA strands among
organisms
Binomial nomenclature – scientific way of naming organisms; each organism is given
a scientific name based on its genus and species
Phylogeny – study of the evolutionary histories of organisms
Systematics – discipline focused on determining the evolutionary relationships of
different organisms
Classification of Life
Organization of Life
Eukaryotes (Eukaryota)
A. Protists (Kingdom Protista)
• Bryophytes: land plants with no vascular system, consist of liverworts, hornworts, and
mosses
• Ferns: majority of plants during the Carboniferous Period (major source of fossil fuels),
reproduce using spores
• Gymnosperms: cone-bearing plants that have seeds with unenclosed ovaries
• Angiosperms: seeds grow inside a fruit (encasement that is the matured ovary of the
flower)
• Monocots: angiosperms that only have one cotyledon in the seed
• Dicots: angiosperms with two cotyledons in the seed
a. Invertebrates
Phylum Characteristic Examples
Porifera No true tissues but have choanocytes Sponges
Cnidaria Have stinging structures, radially symmetric, Hydras, Jellyfish
gastrovascular cavity
Platyhelminthes Dorsoventrally flat, unsegmented, Flatworms
gastrovascular cavity
Mollusca Bilaterally symmetrical Snails, Mollusks
Annelida Segmented body wall and internal organs Earthworms
❖ ECOLOGY
Population – group of organisms of the same species living in the same location
Population Ecology
● Population Density number of organisms divided by area
● Immigrants individuals arriving in the area
● Emigrants individuals leaving the area
● Carrying Capacity maximum population an area can support
Competitive Exclusion- survival of only one between or among two or more species
competing for identical resources in a particular habitat