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WHEY PROTEIN–CHOOSE THE BEST
Whey Protein Concentrate –
A Brief Summary By: Michael Colgan The quality of whey protein concentrate supplements depends on: 1. Breeding and nutrition of the cows. 2. Method of extraction of the protein. 3. The proportion of whey in the supplement. 1. Breeding and Nutrition of the Cows Breeding and nutrition of the cows determines the quality of the protein in the milk. Most whey proteins today come from CAFOs (Confined Animal Feeding Operations), concrete yards in which the animals are fed largely on waste fat, corn, and pelleted plant refuse. CAFO animals and their proteins are poor because cows are ruminants with a highly evolved fermentation tank, the rumen, holding a resident population of microbes specifically designed to ferment grass and humus. The rumen is not designed to use fat, corn, and plant refuse, which is largely why the cows also have to be fed antibiotics and hormones, just to keep them alive. Some labels say “grass-fed” which legally means that the animals in the CAFOs are fed a certain proportion of pelleted dried grass clippings, the proportion depending on state and local regulations. These are still inferior animals, because the cow system is designed to eat fresh grass and humus, with its rich content of phytochemicals and enzymes that are destroyed by drying and pelleting the grass. Some labels say “organic” which legally means that the cows can still be fed on corn and fat, but must have access to a narrow strip of pasture. Some I have seen are not pasture any more, but just trampled mud with nary a speck of grass left. Others I have seen are gated to protect the meagre amount of grass, with the cows given one hour a day to feed on pasture. Ruminants that evolved to be continuous grazers do not fare well on this scheme. Best proteins come from pasture-fed free-range animals, where their miraculous system, which co-evolved with the pasture, can have its natural diet. New Zealand is one of the few places that still raise most milk cows on pasture. Eleven thousand small dairy farmers form the cooperative that sells New Zealand whey protein concentrate today. I did research on the milk proteins there for what was then the New Zealand Dairy Board, while at the University of Auckland. 2. Method of Extraction of the Protein In science, the constituents of milk are determined after removing the water. Milk is 27% protein: 22% of milk is the main milk protein called casein; 5% of milk is whey protein; 1 gram per 20 grams of dried milk. Milk is 37% lactose (milk sugar). Milk is 30% fat. The rest 6% is calcium, other minerals, and ash. Total 100% (Some readers may note that the above figures do not agree with the way milk is labelled for commercial purposes. When you buy full fat milk, the label says 4% fat, but that is because they are counting the water content as well. Without the water, “4% milk” is actually 30% fat, a high fat food.) Many cheap protein concentrates are hydrolyzed, that is, the milk is broken down and proteins extracted by heat, and/or acids or salts. These proteins are then termed “denatured”. The amino acid content remains the same, but biologically, the protein molecule is damaged. The worst damage is the destruction of the bonds between pairs and trios of amino acids. These bonds create the unique chemical shapes, the information “keys” which fit the enzyme “locks” in your body to turn on protein functions. Without these keys, you can eat all the denatured whey protein concentrate you like, but hardly any gets turned into body tissue. This problem was discovered in the 1980s, from whey protein use in hospitals. Only the undenatured whey worked to prevent sarcopenia in patients with wasting diseases. Undenatured whey protein concentrate is now the hospital protein of choice, not only because it improves nitrogen balance, but also because of its ease of digestion and lack of detrimental effects on the compromised organs of patients.1 The way to extract milk proteins undamaged was largely developed in New Zealand, and is termed cross-flow membrane extraction technology. I have successfully used whey proteins extracted in this way with many world champion athletes over the last 25 years. 3. The Proportion of Whey in the Supplement Whey protein concentrate powders come in more than 100 different mixes. The early mixes were dried skim milk powders. They are still used for multiple products. Skim milk powders are semi-sweet because they are more than 50% lactose (milk sugar). Not desirable. Today, to legally to call a powder “whey protein concentrate” it has to contain at least 29% whey protein. There are dozens of these whey protein mixes, used for specific food making purposes. The whey protein content ranges from 29% to 89%. The less the whey, the more lactose, fat, and casein. Yet they are all labelled “whey protein concentrate” when sold in tubs and drinks as nutritional supplements. Buyer beware. High quality supplements for human muscle, immunity, insulin metabolism, and increased production of, glutathione, our major endogenous antioxidant, contain 70-89% whey protein. Whey protein isolate is further refined to contain 90% to 95% whey protein. You can work it out from the label. A vanilla supplement for example, with a serving size of 23 grams, may be labelled to provide 18 grams of protein, 2 grams of carbohydrate (milk sugar) and 1.5 grams of fat. The remaining 1.5 grams is minerals and ash, and any added chemicals such as lactase and flavoring. With this level of extraction, the protein contains about 1.0 grams of casein and 17 grams of whey protein. The proportion of whey is thus 17 divided by 23 = 74%. This is a whey protein concentrate I would use. How much Whey? From 30 years of working with athletes, protein needs for an athlete in training are 1.5-1.9 grams per kg lean mass per day. Body fat does not need protein to sustain it, so you should not count your body fat weight.1 Taking the lower level of the range, if you are 80kg (176 lbs), at 10% body fat (8kg, 17.6 lbs), you have 72 kg (158 lbs) of lean mass. To optimize your training, you need 72 x 1.5 = 108 grams of first quality protein daily. Whey protein concentrate will reduce body fat, increase lean mass, and optimise nitrogen balance better than other meat or vegetable proteins.1-17 It has a higher biological value. Today that is measured by the Protein Digestibility Corrected Amino Acid Score (PDCAAS). High quality whey protein concentrates have scores of 104-114 in science, compared with the 100 score of whole egg, the next best protein. On labels, however, you cannot claim scores of over 100. The body can absorb only 30-40 grams of whey protein concentrate at a meal, so you have to split the intake over several meals per day. If you are working out, the best split is a shake in the morning, then one immediately after workout, with a smaller supplementary shake in the evening. Whey protein concentrate at the same level as used by athletes (1.5 grams per kg) works just as well for people trying to lose weight. It is shown to increase fat oxidation through thermogenesis, improve insulin function, maintain lean mass on reduced calorie diets, and reduce appetite and net food intake.1-17 Research also shows that high quality whey protein concentrate improves lipid profiles, and reduces levels of C-reactive protein, the main inflammatory marker of heart disease.1-17 It is a food that’s hard to beat. Visit our website and see the products with the Right Whey Protein, 1. Colgan M. The Right Protein for Muscle and Strength. Vancouver: Apple Publishing, 1998. 2. Boirie Y, Dangin M, Gachon P, Vasson MP, Maubois JL, Beaufrere B. Slow and fast dietary proteins differently modulate postprandial protein accretion. Proc Natl Acad Sci. 1997;94:14930–14935. doi: 10.1073/pnas.94.26.14930 3. Dangin M, Boirie Y, Garcia-Rodenas C, Fauquant J, Callier P, Ballevre O, Beaufrere B. The digestion rate of protein is an independent regulating factor of postprandial protein retention. Am J Physiol Endocrinol Metab. 2001;280:E340–E348. 4. Layman D. Protein quantity and quality at levels above the RDA improves adult weight loss. J Am Coll Nutr. 2004;23:631S–636S 5. Halton TL, Hu FB. The effects of a high protein diets on thermogenesis, satiety and weight loss: a critical review. J Am Coll Nutr. 2004;23:373–385. 6. Rufian-Henares JA, Delgado-Andrade C, Jimenez-Perez S. Assessing nutritional quality of milk-based sport supplements as determined by furosine. Food Chemistry. 2007;101:573–578. doi: 10.1016/j.foodchem.2006.02.016. 7. Sindayikengera S, Wen-shui X. Nutritional evaluation of caseins and whey proteins and their hydrolysates from Protamex. J Zhejiang Uni. 2006;7:90–98. doi: 10.1631/jzus.2006.B0090. 8. Bilsborough S, Mann N. A review of issues of dietary protein intake in humans. Int J Sport Nutr Exerc Metab. 2006;16:129–152. 9. Johnston CS, Tjonn SL, Swan PD. High-protein, low-fat diets are effective for weight loss and favorably alter biomarkers in healthy adults. J Nutr. 2004;134:586–91. 10. Hu FB, Stampfer MJ, Manson JE, Rimm E, Colditz GA, Speizer FE, et al. Dietary protein and risk of ischemic heart disease in women. Am J Clin Nutr. 1999;70:221–227. 11. Pins JJ, Keenan JM. Effects of whey peptides on cardiovascular disease risk factors. J Clin Hypertens. 2006;8:775–82. doi: 10.1111/j.1524-6175.2006.05667. 12. Bistran BR, Winterer J, Blackburn GL, Young V, Sherman M: Effect of a protein-sparing diet and brief fast on nitrogen metabolism in mildly obese subjects. , J Lab Clin Med, 1997;89:1030– 1035, . 13. Feinman RD, Fine EJ: Thermodynamics and metabolic advantage of weight loss diets. Metab Syn Relat Dis 2003;1:209– 219. 14. Hill JH, Blundell JE: macronutrients and satiety: The effects of a high-protein or high- carbohydrate meal on subjective motivation to eat and food preferences. Nutr Behav 1986;3:133–144. 15. Anderson GH, Moore SE: Dietary proteins in the regulation of food intake and body weight in humans. J Nutr, 2004;134 :974S– 979S, . 16. Layman DK, Shiue H, Sather C, Erickson DJ, Baum J: Increased dietary protein modifies glucose and insulin homeostasis in adult women during weight loss. J Nutr 2003;133 :405– 410, . 17. Layman DK, Boileau RA, Erickson DJ, Painter JE, Shiue H, Sather C, Christou DD: A reduced ratio of dietary carbohydrate to protein improves body composition and blood lipid profiles during weight loss in adult women. J Nutr. 2003;133 :411– 417.
[Physical Review E 2010-oct 22 vol. 82 iss. 4] Guven, Jemal_ Vázquez-Montejo, Pablo - Spinor representation of surfaces and complex stresses on membranes and interfaces (2010) [10.1103_PhysRevE.82.041604] - libgen.li
[Physical Review E 2010-oct 22 vol. 82 iss. 4] Guven, Jemal_ Vázquez-Montejo, Pablo - Spinor representation of surfaces and complex stresses on membranes and interfaces (2010) [10.1103_PhysRevE.82.041604] - libgen.li