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    KFDV

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    Vishnu Reddy Vardhan Pulimi
    Kyasanur Forest disease (KFD) is caused by the Kyasanur Forest disease virus (KFDV) and was first identified in 1957 in the Kyasanur Forest of Karnataka, India. Since then, between 400-500 human cases are reported annually. KFDV is transmitted to humans via tick bites from Haemaphysalis spinigere ticks or contact with infected monkeys. Symptoms include sudden onset of fever, headache, and severe muscle pain followed by bleeding problems. There is no vaccine treatment, but supportive care in hospitals is important. Prevention efforts include wearing protective clothing and using tick repellents in endemic areas.

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    KFDV

    Uploaded by

    Vishnu Reddy Vardhan Pulimi
    124 views18 pages
    Kyasanur Forest disease (KFD) is caused by the Kyasanur Forest disease virus (KFDV) and was first identified in 1957 in the Kyasanur Forest of Karnataka, India. Since then, between 400-500 human cases are reported annually. KFDV is transmitted to humans via tick bites from Haemaphysalis spinigere ticks or contact with infected monkeys. Symptoms include sudden onset of fever, headache, and severe muscle pain followed by bleeding problems. There is no vaccine treatment, but supportive care in hospitals is important. Prevention efforts include wearing protective clothing and using tick repellents in endemic areas.

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    KYASANUR FOREST DISEASE

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    kfdv

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    Kyasanur Forest disease (KFD) is caused by the Kyasanur Forest disease virus (KFDV) and was first identified in 1957 in the Kyasanur Forest of Karnataka, India. Since then, between 400-500 human cases are reported annually. KFDV is transmitted to humans via tick bites from Haemaphysalis spinigere ticks or contact with infected monkeys. Symptoms include sudden onset of fever, headache, and severe muscle pain followed by bleeding problems. There is no vaccine treatment, but supportive care in hospitals is important. Prevention efforts include wearing protective clothing and using tick repellents in endemic areas.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    124 views18 pages

    KFDV

    Uploaded by

    Vishnu Reddy Vardhan Pulimi
    Kyasanur Forest disease (KFD) is caused by the Kyasanur Forest disease virus (KFDV) and was first identified in 1957 in the Kyasanur Forest of Karnataka, India. Since then, between 400-500 human cases are reported annually. KFDV is transmitted to humans via tick bites from Haemaphysalis spinigere ticks or contact with infected monkeys. Symptoms include sudden onset of fever, headache, and severe muscle pain followed by bleeding problems. There is no vaccine treatment, but supportive care in hospitals is important. Prevention efforts include wearing protective clothing and using tick repellents in endemic areas.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    of 18

    KYASANUR FOREST DISEASE (KFD)

    Introduction
    Kyasanur Forest disease (KFD) is caused by Kyasanur

    Forest disease virus (KFDV), a member of the virus family Flaviviridae. KFDV was identified in 1957 when it was isolated from a sick monkey from the Kyasanur Forest in Karnataka (formerly Mysore) State, India. Since then, between 400-500 humans cases per year have been reported. KFDV can cause epizootics with high fatality in primates.

    The disease was named after the forest

    area where it was first discovered as Kyasanur Forest Disease (KFD) and the virus was named as KFD virus.

    ETIOLOGY
    .KFD is a febrile disease associated with haemorrhage caused by an ARBOVIRUS FLAVIVIRUS.
    KFD virus is member of group-B togavirus. Belong to

    russian spring summer encephalitis(RSSE) group of virus

    TRANSMISSION
    Transmission to humans may occur after a tick

    (HAEMOPHYSALIS SPINIGERE) bite or contact with an infected animal, most importantly a sick or recently dead monkey. No person-to-person transmission has been described.

    Epidemiology

    The number of human cases occurring each year varied from 40 to ~1000 with a mortality rate of 4 to15 percent. All age groups are affected, but the incidence in very young children is low, males are more susceptible than females KFD epizootics in monkeys are also a regular Feature in the area, 2,442 monkey Deaths were recorded from 1957 to 1975

    The number of human cases shows a rising trend over the last 5 years. KFD is mainly seasonal and most cases occur during inter monsoon period that is from December to June. The ecological imbalance caused by the clearing of natural patch of forest may have result in the outbreak of the diseases.

    CLINICAL SIGNS
    After an incubation period of 3-8 days, the symptoms of

    KFD begin suddenly with chills, fever, and headache. Severe muscle pain with vomiting, gastrointestinal symptoms and bleeding problems may occur 3-4 days after initial symptom onset. Patients may experience abnormally low blood pressure, and low platelet, red blood cell, and white blood cell counts BIPHASIC FEVER The estimated case-fatality rate is from 3 to 5% for KFD.

    Diagnosis
    Diagnosis can be made in the early stage of illness by

    molecular detection by PCR or virus isolation from blood. Later, serologic testing using enzyme-linked immunosorbent serologic assay (ELISA) can be performed.

    Diagnosis of KFD could be arrived at by isolation of

    the virus from acute serum by inoculation of the suckling mice.

    Treatment
    There is no specific treatment for KFD, but early

    hospitalization and supportive therapy is important. Supportive therapy includes the maintenance of hydration and the usual precautions for patients with bleeding disorders.

    prevention
    Additional preventative measures include insect

    repellents and wearing protective clothing in areas where ticks are endemic. Tick repellents such as DEET, DMP, DBP provide 90-100% protection against tick bite.

    vaccination
    NIV has developed an inactivated chick

    embryo tissue culture vaccine against KFD. This vaccine evokes neutralizing antibodies response in about 70% of the vaccinated persons. The technology has been transferred to the Karnataka Public Health Department for production and vaccination.

    references
    Elements of veterinary public health

    A.T.SHERIKAR V.N.BACHHIT D.C.THAPIYAL

    Thank you
    SUBMITTED BY; SAURABH TIWARI TV/2011-058

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