Journal BEDAH
Journal BEDAH
Journal BEDAH
Background
Open fracture
fracture
involving the
communication
of the bone
through the skin
and with the
external
environment
are considered
to be
contaminated
wound
A key issue in
treatment is the
prevention of
infec- tion, which
can occur in
association with as
many as 50% of
open fractures.
Strategies to minimize
infection include copious
irrigation, debridement,
optimum fracture repair, and
administration of antibiotics
Result of
Culture of
tissue at
open
fracture
The more severe the
fracture type
(Gustilo-Anderson
type II or III) the
more likely that gram
negative or mixed
bacteria are present
gram-positive
bacteria are most
common in association with GustiloAnderson type-I
fractures
Therefore,
we
undertook
a
systematic review and metaanalysis
of
the
available
evidence
from
randomized
controlled trials to assess
Methods
We followed the PRISMA
(Preferred Reporting Items for
Systematic Reviews and MetaAnalyses) guidelines for
reporting systemic reviews
Eligibility
Criteria
We
included
randomized
clinical trials in which :
(1) the patients had presented
with one or more open
fractures involv- ing the arms
and legs,
(2) an antibiotic prophylactic
regimen was compared with
any other regimen or with no
antibiotic prophylaxis, and
(3)
the
incidence
of
postoperative infection was
reported as one of the clinical
outcomes.
We excluded :
studies addressing the use of
antibiotics in patients with
known infections
studies
of
patients
with
fractures involving the fingers
or toes;
and studies restricted to
patients with gunshot wounds,
injuries from bomb explosions,
or HIV/AIDS
Keywords
antibiotics, antimicrobial, antibiotic prophylaxis, open fracture,
compound fracture, Gustilo- Anderson type, fracture fixation,
nonunion, infection, and the names of specific anti- biotics
duration of follow-up;
population characteristics,
intervention data
allocation concealment;
Result
Study
Identification
The risk of bias was high in all studies except for those of
Johnson et al and Moehring et al which had a moderate risk
of bias.
Conclusions
Discussion
Critical Appraisal
Kriteria
Deskripsi Judul
Menggambarkan isi
utama penelitian,
menarik dan tanpa
singkatan
Korespondensi penulis
Abstrak
No.
Kriteria
Pendahuluan
No.
Kriteria
Kriteria
Waktu +, tempat -
Populasi Sumber
Teknik sampling
Kriteria inklusi
Kriteria eksklusi
Blind
10
Uji statistik
11
Program komputer
12
Penentuan Subjek
Hasil
No.
Kriteria
Jumlah subjek
Tabel Karakteristik
Pembahasan, Kesimpulan,
Daftar Pustaka
No.
Kriteria
Keterbatasan penelitian
Saran Penelitian
Aplikasi
Pertanyaan
Jawaban
Tidak
Ya
Ya
Terima Kasih