Types of Coating Pans
Types of Coating Pans
Types of Coating Pans
M.RAGHUVARAN
M.PHARM 2nd SEM
(PHARMACEUTICS)
UNIVERSITY COLLEGE OF PHARMACEUTICAL SCIENCES
KAKATIYA
UNIVERSITY
CONTENTS:
1)COATING PROCESSES
1.film coating
2 .sugar coating
Sugar
coating
Traditionally sugar coatings formed the bulk of coated tablets but today film coatings
are the more modern technology in tablet coating.
Description of tablets: Smooth, rounded and polished to a high gloss.
Process: Multistage process involving 6 separate operations.
Example of sugar coated
Brufen POM
tablets
Available in 200mg and 400mg
strength
Premarin POM
Conjugated oestrogens 625mcg
(maroon) and 1.25mcg (yellow)
Colofac P
Mebeverine hydrochloride
100mg Round, white, sugar
coated
Kalms GSL
45mg Hops powder,90mg
Gentian powdered extract, and
135mg Valerian powdered
extract
FILM COATING
The solution is sprayed onto a rotating tablet bed followed by drying, which
facilitates the removal of the solvent leaving behind the deposition of thin film of
coating materials around each tablet.
Enteric coating
The technique involved in enteric coating is protection of the tablet core from
disintegration in the acidic environment of the stomach by employing pH sensitive
polymer, which swell or solubilize in response to an increase in pH to release the
drug.
Enteric
coated aspirin E.g. Micropirin
75mg EC tablets
COATNG PANS
1) PLG SYSTEM
2) GS SYSTEM
A)ACCELA-COTA PAN
3) inlet a ir is by a plenum in
contact with the top o f the
pa n.
4) a ir is exha usted by a plenum
loca ted belo w the pa n.
B)HI-COATER PAN
1. Installation qualification
(IQ)
2. Operational qualification
(OQ)
3. Performance qualification
(PQ)
Installation qualification (IQ)
Equipment manufacturers,
Purchase order no:
Model number
Serial num
Company assigned equipment num,
The location of the equipment
Required documentation
Record the equipment and manufacturers
operation and maintenance manual and
drawings in the below table.
Verify
that the measured speed is with in
10% of the variable speed of 12-36rpm.
Record
the instruments used to measure the
volume of the water and operating time
PERFORMANCE QUALIFICATION
Once it has been established that the
equipment is properly installed and functioning
within specified operating parameters, it must
be shown that the coating pan can operate
reliably under routine, minimum and maximum
operating conditions.
TABLET COATING PAN OPERATION
The pan operation is tested to document the
performance and speed of the tablet coating
pan using placebo tablets and orange opadry
coating medium.a tachometer will be required.
Procedure;
. Fill the pan with placebo tablets and record the placebo and spraying materials used in a table
. Enter the set points and start spraying the tablets after the steady state is achieved.record the results in a table
.measure speed of the coating pan with a calibrated and record the results in a table
.verify that the measured speed is with in 10% of the variable speed from 12 to36 rpm.
Coating pan speed specification = 12 to36 rpm
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