Brachial Plexus Asia in

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BRACHIAL PLEXUS INJURY IN

NEONATES

LOURDES ASIAIN
February 2005
BACKGROUND

1764 Obstetrical brachial palsy described by Smellie.

1874 Wilhelm H. Erb described brachial plexus


paralysis in adults which involved the upper roots and
described certain types of “delivery paralysis”. He
credited Duchenne for describing the brachial palsy
following delivery in affected newborns.

1885 Augusta Klumpke first described the clinical


picture resulting from injury to lower roots.
EPIDEMIOLOGY
Incidence of brachial plexus palsy is reported to affect
0.5 to 1.9 per 1000 live births (Bar et al 2001)

90% Erb palsy

Most common on the right side because the most common


delivery presentation is left occiput anterior vertex.

Associated with: pre and gestational diabetes


older maternal age
increased BW, LGA
Newborns with BP injuries have a higher incidence of low
Apgar scores of less than 7 at 1 and 5 mins and of asphyxia
than matched controls
EPIDEMIOLOGY

Brachial plexus palsy occurs in 26% of cases of shoulder


Dystocia

Both Shoulder dystocia and brachial plexus palsy are more


common in LGA babies and Infants of diabetic mothers

Infants of diabetic mothers have a higher incidence of


permanent impairment

In infants of diabetic mothers, the macrosomic process


affects the trunk but not the head (large biacromial diameter)
The head shoulder disproportion is difficult to predict in
Utero.
EPIDEMIOLOGY

Clavicular fractures are often associated with shoulder


dystocia , but the incidence of brachial palsy in these
Cases is only 11%.

Clavicular fracture =more mobility of shoulder

Not always associated with difficult delivery (Intrauterine


Maladaption palsy). Cases of in utero origin supported by
EMG findings if denervation at birth.
ANATOMY
ANATOMY
Brachial plexus is comprised of a group of nerves
arising form the nerve roots C5-T1.

The uppper (C5-C6) roots innervate the deltoid, spinati,biceps,


brachioradialis, biceps supinator and flexor muscles of
the forearm.

The lower roots (C7-T1) innervate the intrinsic muscles


of the hand.

The phrenic nerve, arising from C3-C5 can be involved


resulting in ipsilateral diaphragmatic paralysis causing a
decrease in thoracic space, tidal volume and vital capacity.

Involvement of the sympathetic nerves from T1 that give rise


to the sup cervical symp ganglion can result in Horner Synd.
HORNER SYNDROME

Ptosis
Miosis and
anhydrosis
Stretch, tear, compression or
avulsion of the nerves
usually after forceful lateral
deviation of the head from
the shoulders during
delivery. Recent studies
suggest intrinsic forces
PATHOGENESIS (uterine contractions).
Clinical Manifestations:

Asymmetric Moro reflex

Erb palsy caused by the disruption of the upper brachial


plexus. Posture of adduction and inward rotation at the
shoulder with extension and pronation
at the elbow and flexion of the
fingers = WAITER’S TIP

Klumpke= absent grasp reflex


of the hand
Clinical Manifestations

If phrenic nerve is involved, as mentioned earlier


respiratory distress may be present.
DIFFERENTIAL DIAGNOSIS
Cervical Injury

Cervical Spine injury

Dislocation of upper extremity/fractures of upper


extremity

Intrauterine maladaptation palsy

The physical findings of BP palsy are so unique so it is


difficult to mistaken if for other diagnosis.
DIAGNOSTIC WORKUP

Evaluation can be undertaken by multiple modes of


Imaging.

EMG

MRI

Chest X ray

Real time UltraSonography


MANAGEMENT
The majority of patients with brachial plexus palsy
Dx at birth will recover from neurologic deficit.
Those who do not recover during 3-6month period will
Require surgical intervention.

1-2 week rest of affected limb

Early referral to upper extremity clinic and PT

Caregivers should be instructed on how to handle baby:


No traction of affected arm, no pressure under axila.
Baby to be carried in football hold
MANAGEMENT
Surgical
•Exploration
•Neurolysis
•Excision of scar tissue
•Nerve grafting (local end to end anastomosis or remote
nerve transplant)

•Surgical plication in case of diaphragmatic involvement

Special considerations in post surgical care:


Edema of neck and compromise of airway
Injury to vagal and laryngeal nerves
Risk for meningitis
PROGNOSIS
Study by Noetzel et al (2001) followed 80 patients
with BP injury who did not recover by 2 weeks of
age.

Used the BMRC scales for evaluating muscle


strength and found:
Complete recovery in 66%
Mild impairment in 11%
Moderate weakness was seen in 9%
Severe weakness in 14%

When associated with phrenic nerve palsy and


diaphragmatic paralysis, there is more likelihood of
need for surgery for recovery.
REFERENCES
 Brachial plexus palsy in neonates
John B Cahil, Medlink

Brachial plexus injury and


obstetrical risk factors. Int J
Gynecol Obst 2001;73 (1) 21-5

Brachial plexus injuries, emedicine


Aug 2004
THANK YOU

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