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    Scabies Infection - A Nelson's Series Lecture

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    Ron Christian Neil Rodriguez
    This document provides information about scabies infection through a lecture on the topic. It defines scabies as a mite infection caused by Sarcoptes scabiei that spreads through prolonged skin contact. It describes the most common infection sites in children and adults. It explains the pathogenesis of scabies mites burrowing under the skin and laying eggs. The clinical manifestations of scabies are described as intense pruritus and inflammatory papules localized to areas like the hands and feet. Diagnosis involves finding mites or eggs under microscopic examination of skin scrapings. Treatment recommended is permethrin cream applied to the entire body.

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    Scabies Infection - A Nelson's Series Lecture

    Uploaded by

    Ron Christian Neil Rodriguez
    59 views10 pages
    This document provides information about scabies infection through a lecture on the topic. It defines scabies as a mite infection caused by Sarcoptes scabiei that spreads through prolonged skin contact. It describes the most common infection sites in children and adults. It explains the pathogenesis of scabies mites burrowing under the skin and laying eggs. The clinical manifestations of scabies are described as intense pruritus and inflammatory papules localized to areas like the hands and feet. Diagnosis involves finding mites or eggs under microscopic examination of skin scrapings. Treatment recommended is permethrin cream applied to the entire body.

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    Scabies Infection – A Nelson’s Series Lecture

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    This document provides information about scabies infection through a lecture on the topic. It defines scabies as a mite infection caused by Sarcoptes scabiei that spreads through prolonged skin contact. It describes the most common infection sites in children and adults. It explains the pathogenesis of scabies mites burrowing under the skin and laying eggs. The clinical manifestations of scabies are described as intense pruritus and inflammatory papules localized to areas like the hands and feet. Diagnosis involves finding mites or eggs under microscopic examination of skin scrapings. Treatment recommended is permethrin cream applied to the entire body.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    59 views10 pages

    Scabies Infection - A Nelson's Series Lecture

    Uploaded by

    Ron Christian Neil Rodriguez
    This document provides information about scabies infection through a lecture on the topic. It defines scabies as a mite infection caused by Sarcoptes scabiei that spreads through prolonged skin contact. It describes the most common infection sites in children and adults. It explains the pathogenesis of scabies mites burrowing under the skin and laying eggs. The clinical manifestations of scabies are described as intense pruritus and inflammatory papules localized to areas like the hands and feet. Diagnosis involves finding mites or eggs under microscopic examination of skin scrapings. Treatment recommended is permethrin cream applied to the entire body.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    of 10

    SCABIES INFECTION – A

    NELSON’S SERIES LECTURE


    Ron Christian Neil T. Rodriguez, MD
    Second Year Resident
    Department of Pediatrics
    SCABIES INFECTION – SIBLINGS (10/F, 5/M)
    SCABIES INFECTION

     Caused by the female mite (Sarcoptes scabiei var.


    hominis)
     Spread is most dependent on two factors:
    extent and duration of physical contact with an
    affected individual
     Children and sexual partners of affected
    individuals are most at risk
     Most common infections sites: interdigital and
    popliteal folds, groin, inframammary folds,
    ankles, buttocks, umbilicus (older children)
    SCABIES INFECTION

     Adult female mite measures


    approximately 0.4 mm in length, has
    4 sets of legs, and has a hemispheric
    body marked by transverse
    corrugations, brown spines, and
    bristles on the dorsal surface
    SCABIES INFECTION - PATHOGENESIS

     Mite exudes a keratolytic substance and burrows


    in the stratum corneum, forming a shallow well
    within 30 mins, laying around 10-25 eggs and
    scybala/fecal matter.
     After 4-5 weeks, female mite dies inside the
    burrow. Eggs hatch in 3-5 days, and the
    larvae/nymph achieve maturity in 2-3 weeks.
     Mating then ensues, with a new gravid female
    invading the skin
    SCABIES INFECTION – MANIFESTATION

     Intense pruritus, particularly at night


     Red papules (1-2 mm) – first signs of infection
     Threadlike burrows – classic lesions, but may not
    be seen in infants
     In infants, bullae and pustules are more common
     Infants will often have a diffuse eczematous
    eruption that will involve the scalp, neck, and face
    Presenting Form of Scabies Specific High Risk Population Clinical Manifestations Differential Diagnosis

    Classic Scabies (Scabies vulgaris) Infants and children; sexually active adults; Intense generalized pruritus, worse at night; Dermatitis herpetiformis, drug reactions, eczema,
    men who have sex with men inflammatory pruritic papules localized to finger pediculosis corporis, lichen planus, pityriasis rosea
    webs, flexor aspects of wrists, elbows, axillae,
    buttocks, genitalia, female
    breasts; lesions and pruritus spare the face, head,
    and neck; secondary lesions include
    eczematization, excoriation, impetigo

    Scalp Scabies Infants and children; institutionalized older Atypical crusted papular lesions of the scalp, face, Dermatomyositis, ringworm, seborrheic
    adults; AIDS patients; patients with palms, and soles dermatitis
    preexisting crusted scabies

    Crusted Scabies (Norwegian Institutionalized older adults; institutionalized Psoriasiform hyperkeratotic popular lesions of the Contact dermatitis, drug
    Scabies) developmentally disabled (Down syndrome); scalp, face, neck, hands, feet, with extensive nail reactions, eczema, erythroderma, ichthyosis,
    homeless, especially HIV-positive; all involvement; eczematization and impetigo psoriasis
    immunocompromised patients, particularly common
    those with AIDS or positive for HIV or HTLV-1;
    transplant recipients; patients on prolonged
    systemic corticosteroids and chemotherapy

    Nodular Scabies Sexually active adults; men who have sex with Violaceous pruritic nodules localized to male Acropustulosis, atopic dermatitis, Darier disease,
    men; HIV-positive men > HIV-positive women genitalia, groin, axillae, representing lupus erythematosus, lymphomatoid papulosis,
    hypersensitivity reaction to mite antigens papular urticaria, necrotizing vasculitis, secondary
    syphilis
    SCABIES INFECTION - DIAGNOSIS

     Definitive diagnosis is obtained by finding the


    parasite and the eggs, the former of which is
    found at the terminal end of a burrow, while the
    latter can be found near the start of a fresh
    burrow
     Skin scrapings immersed in mineral oil then
    placed in KOH solution will provide an good
    sample of the eggs and mite, if present
    SCABIES INFECTION - TREATMENT

     Treatment: Permethrin 5% cream applied to entire body


    for 8-12 hours.
     Alternatives: Lindane 1% lotion or cream, sulfur
    ointment, Crotamiton 10% lotion or cream (Crotamiton
    is recommended for infants)
     Lindane can cause neurologic side effects, hence only
    given in those without history of any neurologic diseases
     ALL household members must be treated at the SAME
    time
     Itching may persist for 7-10 days after successful therapy
    and may need to be supplemented with topical
    corticosteroids
    THANK YOU

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