Anesthesia For Pituitary Lesions: Rialph Engel D. Guia
Anesthesia For Pituitary Lesions: Rialph Engel D. Guia
Anesthesia For Pituitary Lesions: Rialph Engel D. Guia
PITUITARY LESIONS
• Two parts:
• Front (anterior) lobe
• Back (posterior) lobe
• Connected to the
hypothalamus
• Anterior lobe: hormones
• Posterior lobe: nerve impulses
Blood Supply
anterior pituitary
adrenocorticotropic
hormone (ACTH)
adrenal cortex
Adrenocorticotropic Hormone
• Follicle-stimulating hormone,
luteinizing hormone
• Testes → sperm
• Ovaries → eggs
• Sex organs → sex hormones
• Placental hormone, human
chorionic gonadotropin (hCG)
FSH
• Excess
• Thickens the bones of the jaw,
fingers and toes
• Sweating, pressure on nerves,
muscle weakness, insulin resistance
• Children: gigantism
• Adults: acromegaly
Growth Hormone
• Deficiency
• Children: growth failure,
development of a short stature,
delayed sexual maturity
• Adults: increased osteoclast activity,
relative increase in fat mass, relative
decrease in muscle mass
Prolactin
• Negative-feedback loop
• Dopamine – prolactin-inhibiting hormone
• Somatostatin – GH release–inhibiting hormone
• GH-releasing hormone
• Corticotropin-releasing hormone
• Gonadotropin-releasing hormone
• Tyrotrophin-Releasing Hormone (TRH)
Anterior Pituitary Hypersecretion
Clinical Features