Congestive Heart Failure

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CONGESTIVE

HEART FAILURE
DEFINITION
• Definition: Failure of cardiac output to meet
metabolic needs of the body

• Cardiac Failure results in inadequate oxygen


delivery to body tissues

• Compensated Heart Failure: compensatory


mechanisms increase the cardiac output and the
oxygen delivery

• Decompensated Heart Failure: compensatory


mechanisms start failing and cardiac output starts
falling
CARDIAC OUTPUT
• Cardiac Output = Heart Rate X Stroke Volume

• Stroke volume is dependent on three factors:

• Preload – (blood volume overload, End Diastolic Volume)

• Afterload – resistance (pressure) against which the heart must pump blood, systemic vascular resistance

• Contractility of heart – Cardiac Performance

Normal cardiac output in neonates 150 to 300 mL/kg/min


FACTORS AFFECTING CARDIAC
PERFORMANCE
• Cardiac output depends on: stroke volume and heart rate.

• Stroke volume is dependent on three important factors:


Preload,
1. Afterload and
2. Contractility.
• Preload = volume of blood received
by the heart.

Basically, preload is stretch.

• Afterload = pressure or resistance the


heart has to overcome to eject blood.

• Afterload is squeeze.
CLINICAL ASSESSMENT OF SEVERITY IN
CHILDREN
MODIFIED ROSS HEART FAILURE
CLASSIFICATION IN CHILDREN
CLASS INFANT CHILD

Asymptotic Asymptotic
I
No limitations No limitations.
Mild Tachypnea or diaphoresis with
II feeding Dyspnoea on exertion
No growth failure

Marked Tachypnea or diaphoresis


with feeding Marked dyspnoea on exertion
III
Prolonged feeding times FTT
FTT

Tachypnea, retractions, grunting, or Tachypnea, retractions, grunting, or


IV
diaphoresis at rest diaphoresis at rest
CLASSIFICATION OF HEART
FAILURE
(1) According to the course of disease

1) Acute HF

2) Chronic HF

2)According to the cardiac output (CO)

1) Low-output HF: due to volume overload, pressure overload & contractility problems.

2) High-output HF: Heart Rate is primarily affected; 3A(Anemia, Arrhythmia, AV Fistula)


CLASSIFICATION OF HEART
FAILURE
(3) According to the location of heart failure

1) Left –side heart failure (LHF)

2) Right-side heart failure (RHF)

3) Biventricular failure (whole heart failure)

(4)According to the function impaired CARDIAC TAMPONADE. A SERIOUS CARDIAC CONDITION


WHERE BLOOD, FLUID, OR AIR FILL THE PERICARDIAL
SAC THAT ENCASES THE HEART CAUSES EXTREME
COMPRESSION OF ALL FOUR CHAMBERS OF THE HEART
1) systolic failure : Myocarditis, hypertension TROUBLE PUMPING BLOOD TO MAJOR ORGANS!
CLASSIFICATION OF HEART FAILURE

2) Diastolic failure: restrictive cardiomyopathy, cardiac tamponade.


ETIOLOGY
• Congenital Heart Disease – VSD, ASD, PDA
• Rheumatic Fever, Rheumatic Heart Disease –
MR
• Cardiac Arrhythmia – SVT, VT
• Severe anemia
• Pericardial effusion
• Hypertension – Renal diseases (Acute
glomerulonephritis, CKD)
• Pulmonary hypertension (cor-pulmonale)
• Cardiomyopathy
SYMPTOMS
• Infants:
• Feeding problems,
sweating
• Oliguria
• Growth failure

• Older children:
• Exertional dyspnea
• Fatigue
• Edema
• Palpitation
• Pain abdomen
TIC
EVALUAT
• X-ray Chest (cardiomegaly)

ION
• ECG – (ventricle hypertrophy)

• Echocardiography –
Low Ejection Fraction (N = 55-65%)

• Oxygen saturation (Pulse oximetry)


– low in pulmonary edema
OTHER INVESTIGATIONS
• CBC
• Electrolytes
• Cardiac Biomarkers – increase in ventricular dilation(for heart
damage or stress due to low oxygen)
Brain natriuretic peptide (BNP) – more than 100 pg/mL

N-terminal prohormone BNP (NT-pro BNP)(to check intravascular


blood volume and vascular tone)
• Liver Function Tests
• Renal Function Tests
COMPLICATIONS
• Cardiac • Liver dysfunction
Arrhythmia
• Renal failure

• Thrombo- • Electrolyte
embolism Imbalance

• Failure to thrive –
• Repeated chest
low weight and
infections
height

• Pulmonary edema
MANAGEMENT
• Diuretics eg. Furosemide

• Digoxin

• ACE inhibitors (ACEI, ARB) eg.:- Captopril, Enalapril.

• Neprilysin inhibitors (Sacubitril-valsartan)

• Beta-blockers (metoprolol, and propranolol)

• Treat the cause of Heart Failure

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