Cell surface HLA-DR-invariant chain complexes are targeted to endosomes by rapid internalization (Q24561527)

1

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C L Teletski

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E Stang

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E O Long

Proceedings of the National Academy of Sciences of the United States of America

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language of work or name

English

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publication date

15 September 1993

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published in

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volume

90

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issue

18

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page(s)

8581-5

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cites work

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A novel di-leucine motif and a tyrosine-based motif independently mediate lysosomal targeting and endocytosis of CD3 chains

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Relationship between invariant chain expression and major histocompatibility complex class II transport into early and late endocytic compartments.

27 September 2017

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Role for intracellular proteases in the processing and transport of class II HLA antigens

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Lysosomal acid phosphatase is transported to lysosomes via the cell surface

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Co-localization of molecules involved in antigen processing and presentation in an early endocytic compartment

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Invariant chain targets HLA class II molecules to acidic endosomes containing internalized influenza virus

27 September 2017

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Proteolysis of the class II-associated invariant chain generates a peptide binding site in intracellular HLA-DR molecules

27 September 2017

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Stable surface expression of invariant chain prevents peptide presentation by HLA-DR.

27 September 2017

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Antigen processing for presentation to CD4+ T cells

27 September 2017

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Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding

27 September 2017

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The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route

30 May 2018

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Rapid intracellular pathway gives rise to cell surface expression of the MHC class II-associated invariant chain (CD74).

30 May 2018

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Processed antigen binds to newly synthesized MHC class II molecules in antigen-specific B lymphocytes

30 May 2018

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MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding

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Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments

30 May 2018

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Human major histocompatibility complex class II invariant chain is expressed on the cell surface.

30 May 2018

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Intracellular transport of class II MHC molecules directed by invariant chain.

30 May 2018

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Differential expression and serologically distinct subpopulations of human Ia antigens detected with monoclonal antibodies to Ia alpha and beta chains

28 November 2018

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12 December 2020

Analysis of monoclonal antibodies reactive with human class II beta chains by two-dimensional electrophoresis and Western blotting

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12 December 2020

Mutations in the cytoplasmic domain of the 275 kd mannose 6-phosphate receptor differentially alter lysosomal enzyme sorting and endocytosis

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12 December 2020

Lack of detectable endocytosis of B lymphocyte MHC class II antigens using an antibody-independent technique

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12 December 2020